Accès ouvert
2026
article
OpenAlex
Rebecka Hjort, Ina L. Andersen, Polina Lukina, Kristian Hveem et autres
BACKGROUND & AIMS: The HLA-DQ2.5, -DQ2.2, or -DQ8 allotypes are necessary for celiac disease (CeD) development. Their distribution may vary between adults with known, previously diagnosed CeD and newly diagnosed CeD detected through screening. METHODS: In the population-based the Trøndelag Health Study …
no, nl
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Accès ouvert
2026
article
OpenAlex
Biagio Di Lorenzo, Letícia Camargo Tavares, Cristian Díaz-Muñoz, Francisco Heredia-Fernández et autres
BACKGROUND: Irritable bowel syndrome (IBS) is a complex disorder of gut-brain interaction, with heterogeneous symptoms, no available biomarkers and limited pathogenetic insight. OBJECTIVE: To identify genetic risk factors and actionable mechanisms for future clinical translation in IBS. DESIGN: We conducted a genome-wide …
it, au, us, es, dk, ca, gb, is, ee, lv, nl, qa, tw, no, se, fi
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Accès ouvert
2026
article
OpenAlex
Ida Lindeman, Aengus Officer, Shiva Dahal‐Koirala, Louise Fremgaard Risnes et autres
Abstract Polymorphisms of human leukocyte antigen (HLA) genes confer risks for many human diseases. For predisposing effects relating to T-cell receptor (TCR) recognition of peptide-HLA, the effect can be both selection of the TCR repertoire and preferential presentation of disease-driving epitopes. In …
no, dk, se, us
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Accès ouvert
2025
article
OpenAlex
A.-K. Eriksson Wiklund, Giola Santoni, Cecilia Radkiewicz, Shao-Hua Xie et autres
OBJECTIVES: Helicobacter pylori infection seems to increase the risk of developing pancreatic cancer, but it is unknown whether eradication treatment of this bacterium changes this risk. We hypothesized that the increased risk of pancreatic cancer among individuals infected with Helicobacter pylori decreases …
se, is, no, dk, fi
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2025
article
OpenAlex
Johan Hardvik Åkerström, Giola Santoni, My von Euler‐Chelpin, Helgi Birgisson et autres
INTRODUCTION: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) induce weight loss, and have been associated with an overall decreased risk of esophageal cancer. Obesity is strongly associated with esophageal adenocarcinoma and substantial weight loss may decrease the risk of this malignancy, whereas weight loss …
se, dk, is, no, fi, gb
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Accès ouvert
2025
article
OpenAlex
Kjetil Klaveness Melby, Rebecka Hjort, Knut E. A. Lundin, Eivind Ness‐Jensen
OBJECTIVE: This study aimed to determine whether H. pylori or its antigens affect the age at which coeliac disease (CeD) was diagnosed. Participants over 20 years old from the HUNT4 survey were screened for CeD by measuring serum immunoglobulin A and immunoglobulin …
no, se
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Accès ouvert
2025
article
OpenAlex
Mohammad Sayeef Alam, Brooke N. Wolford, Kristian Hveem, Knut E. A. Lundin et autres
A large proportion of individuals with celiac disease (CeD) remain undiagnosed, often presenting at an older age of onset or with non-classical symptoms compared to diagnosed cases. Such heterogeneity might be related to genetic factors. The aim was to utilize a CeD-screened …
no, nl, se
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Accès ouvert
2025
article
OpenAlex
Heidi Hjelle, Tor Åge Myklebust, Atle van Beelen Granlund, Ann Elisabet Østvik et autres
BACKGROUND: The prevalence of inflammatory bowel disease (IBD) is rising, while the incidence varies between countries. OBJECTIVE: To determine changes in prevalence and incidence of IBD in a Norwegian general population. DESIGN: This study was based on the Trøndelag Health Study (HUNT), …
no, se
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Accès ouvert
2025
article
OpenAlex
Dag Holmberg, Julia Bielik, Giola Santoni, Eivind Ness‐Jensen et autres
Abstract Background Gastroesophageal reflux disease (GERD) is exceedingly common in high-income countries. Non-erosive GERD is increasingly being considered a different entity to erosive GERD, with a more benign disease course but less responsive to antireflux medication. Whether non-erosive GERD responds less well …
se, no, dk, fi, gb
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Accès ouvert
2025
article
OpenAlex
Hejie Wang, Yaxin Qu, Lin Yuan, Zhiqiang Liu et autres
BACKGROUND AND AIM: The effect of Helicobacter pylori (H. pylori) infection and eradication on the risk of gastroesophageal reflux disease (GERD) is still unclear. METHODS: We conducted a systematic review with a comprehensive literature search in the bibliographic databases Embase, Medline, and …
cn, gb, se, us, no
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Accès ouvert
2025
article
OpenAlex
Dag Holmberg, Julia Bielik, Giola Santoni, Eivind Ness‐Jensen et autres
Importance: Gastroesophageal reflux disease (GERD) is very common in high-income countries. Nonerosive GERD is increasingly being considered a different entity from erosive GERD, with a more benign disease course but less responsiveness to antireflux medication. Whether nonerosive GERD responds less well than …
se, no, dk, fi, gb
(code pays fourni par la source)
2025
article
OpenAlex
Frederik Emil Juul, Michael Bretthauer, Peter Holger Johnsen, Faye Samy et autres
BACKGROUND: infection (CDI), but its role in primary CDI is unclear. OBJECTIVE: To investigate the efficacy and safety of FMT in primary CDI. DESIGN: Randomized, open-label, noninferiority, multicenter trial. (ClinicalTrials.gov: NCT03796650). SETTING: Hospitals and primary care facilities in Norway. PATIENTS: toxin in …
no, gb, se
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