Dag Holmberg

P04.3. Long-Term Outcomes of Peroral Endoscopic Versus Laparoscopic Myotomy for Achalasia: A Population-Based Cohort Study

Matthew Allaway, Jane Yan, David Watson, Wilhelm Leijonmarck et autres

Abstract Topic Benign Disease: Esophageal Function and Motility Background Randomised clinical trials have demonstrated non-inferiority of peroral endoscopic myotomy (POEM) to laparoscopic Heller myotomy (LHM) in the treatment of achalasia. However, there is a lack of long-term follow-up data from population-based cohorts …

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The Effect of Prior Proton Pump Inhibitor Use on Gastric Cancer Survival: A Population-Based Cohort Study in the 5 Nordic Countries

Onyinyechi Duru, Giola Santoni, Dag Holmberg, Helgi Birgisson et autres

INTRODUCTION: Proton pump inhibitors (PPIs) might mask gastric cancer symptoms, leading to delayed diagnosis and worse oncological outcomes. However, current evidence is sparse and underpowered. This study aimed to elucidate whether PPI use influences oncological outcomes of gastric cancer in a well-powered …

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1089 MORTALITY RISKS AND CANCER INCIDENCE IN BARRETT'S ESOPHAGUS IN A POPULATION-BASED COHORT STUDY: THE NORDIC BARRETT'S ESOPHAGUS-2 STUDY (NORDBEST2)

Sachin B. Wani, Giola Santoni, Dag Holmberg, My C. von Euler-Chelpin et autres

721 A POPULATION-BASED STUDY TO DEFINE THE OPTIMAL AGE TO STOP ENDOSCOPIC SURVEILLANCE IN PATIENTS WITH BARRETT’S ESOPHAGUS BASED ON SEX AND COMORBIDITY

Sachin B. Wani, Giola Santoni, Amir H. Omidvari, Danica M. van den Berg et autres

1089 MORTALITY RISKS AND CANCER INCIDENCE IN BARRETT'S ESOPHAGUS IN A POPULATION-BASED COHORT STUDY: THE NORDIC BARRETT'S ESOPHAGUS-2 STUDY (NORDBEST2)

Sachin B. Wani, Giola Santoni, Dag Holmberg, My C. von Euler-Chelpin et autres

721 A POPULATION-BASED STUDY TO DEFINE THE OPTIMAL AGE TO STOP ENDOSCOPIC SURVEILLANCE IN PATIENTS WITH BARRETT’S ESOPHAGUS BASED ON SEX AND COMORBIDITY

Sachin B. Wani, Giola Santoni, Amir H. Omidvari, Danica M. van den Berg et autres

Achalasia and Risk of Esophageal Squamous Cell Carcinoma and Adenocarcinoma in a Multinational Study

Wilhelm Leijonmarck, Giola Santoni, Dag Holmberg, Stuart Spechler et autres

BACKGROUND & AIMS: Achalasia appears to increase the risk of esophageal squamous cell carcinoma, but existing evidence relies on small studies that did not adjust for this cancer's main risk factors (ie, smoking and alcohol overconsumption). Whether achalasia increases the risk of …

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Cancer in the Excluded Stomach After Gastric Bypass Surgery for Obesity

Wilhelm Leijonmarck, Giola B. Santoni, Dag Holmberg, von Euler-Chelpin M et autres

OBJECTIVE: To assess whether gastric bypass surgery for obesity increases the risk of adenocarcinoma in the excluded stomach and delays adenocarcinoma diagnosis. BACKGROUND: Gastric bypass might increase adenocarcinoma risk through bile reflux and delay such diagnosis because of anatomical hurdles with endoscopic …

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Survival in post-endoscopy esophageal cancer: a Nordic population-based cohort study

Dag Holmberg, Amalia Liljequist Aspelund, Eivind Ness-Jensen, von Euler-Chelpin M et autres

Background: Post-endoscopy esophageal cancer (PEEC) (i.e. esophageal cancer diagnosed shortly after an endoscopy in which no cancer was found) constitutes about 5%-10% of all esophageal cancers. Long-term survival in PEEC has not been reported previously. Methods: This population-based cohort study included patients …

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Long term use of proton pump inhibitors and risk of stomach cancer: population based case-control study in five Nordic countries

Onyinyechi Duru, Giola B. Santoni, Dag Holmberg, Helgi Birgisson et autres

Abstract Objective To help to clarify whether long term use of proton pump inhibitors is associated with an increased risk of gastric adenocarcinoma by designing a study that considered the existing literature’s methodological weaknesses. Design Population based case-control study using prospectively collected …

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Mortality and Causes of Death After Metabolic Bariatric Surgery in Older Patients

Peter Gerber, Giola B. Santoni, von Euler-Chelpin M, Joonas H. Kauppila et autres

BACKGROUND: Metabolic bariatric surgery leads to improved life expectancy in younger individuals, but whether older (> 60 years) individuals benefit from metabolic bariatric surgery is uncertain. This study examined mortality and causes of death in patients with metabolic bariatric surgery at age …

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Glucagon-Like Peptide-1 Receptor Agonist Treatment and Risk of Esophageal Cancer

Johan Hardvik Åkerström, Giola Santoni, My von Euler‐Chelpin, Helgi Birgisson et autres

INTRODUCTION: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) induce weight loss, and have been associated with an overall decreased risk of esophageal cancer. Obesity is strongly associated with esophageal adenocarcinoma and substantial weight loss may decrease the risk of this malignancy, whereas weight loss …

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