Lennox Graham

The Role of Transportation in the Enrollment of Elderly African Americans into Exercise and Memory Study: GEMS Study

Lennox Graham, Julius S. Ngwa, Oyonumo Ntekim, Oludolapo Ogunlana et autres

BACKGROUND: Understanding the factors driving recruitment and enrollment of African Americans (AA)s in clinical translational research will assure that underrepresented populations benefit from scientific progress and new developments in the diagnosis and treatment of Alzheimer's disease and related disorders. While transportation is …

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Use of a community advisory board to build equitable algorithms for participation in clinical trials: a protocol paper for HoPeNET

Nicole Farmer, Foster Osei Baah, Faustine Williams, Erika Ortiz-Chapparo et autres

INTRODUCTION: Participation from racial and ethnic minorities in clinical trials has been burdened by issues surrounding mistrust and access to healthcare. There is emerging use of machine learning (ML) in clinical trial recruitment and evaluation. However, for individuals from groups who are …

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P2‐589: ASSOCIATION OF DIFFERENT TYPES OF PHYSICAL ACTIVITY WITH PERFORMANCE ON COGNITIVE TASKS IN A PREDOMINANTLY AFRICAN AMERICAN SAMPLE

Sheeba Nadarajah, Jillian Turner, Steven T. Johnson, Julius S. Ngwa et autres

African Americans (AA) have the highest incidence and prevalence of dementia, compared to five other racial groups. In AAs, amnestic mild cognitive impairment is associated with multiple factors including cardiovascular disease. Lower levels of recommended physical activity significantly increase the prevalence of …

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Digital Food Records in Community-Based Interventions: Mixed-Methods Pilot Study

Lauren A. Fowler, Leah Yingling, Alyssa T Brooks, Gwenyth R. Wallen et autres

BACKGROUND: A pressing need exists to understand and optimize the use of dietary assessment tools that can be used in community-based participatory research (CBPR) interventions. A digital food record, which uses a mobile device to capture the dietary intake through text and …

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Associations of Pulse and Blood Pressure with Hippocampal Volume by APOE and Cognitive Phenotype: The Alzheimer’s Disease Neuroimaging Initiative (ADNI)

Julius S. Ngwa, Thomas V. Fungwe, Oyonumo Ntekim, Joanne Allard et autres

BACKGROUND: It is increasingly evident that high blood pressure can promote reduction in global and regional brain volumes. While these effects may preferentially affect the hippocampus, reports are inconsistent. METHODS: Using data from the Alzheimer's Disease Neuroimaging Initiative (ADNI), we examined the …

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Digital Food Records in Community-Based Interventions: Mixed-Methods Pilot Study (Preprint)

Lauren A. Fowler, Leah Yingling, Alyssa T Brooks, Gwenyth R. Wallen et autres

BACKGROUND A pressing need exists to understand and optimize the use of dietary assessment tools that can be used in community-based participatory research (CBPR) interventions. A digital food record, which uses a mobile device to capture the dietary intake through text and …

Examining relationships between perceptions and objective assessments of neighborhood environment and sedentary time: Data from the Washington, D.C. Cardiovascular Health and Needs Assessment

Chaarushi Ahuja, Colby Ayers, Jacob Hartz, Joel Adu‐Brimpong et autres

Sedentary time (ST) and neighborhood environment (NE) are predictors of cardiovascular (CV) health. However, little is known about ST's relationship with NE. We examined associations of perceived and objective NE with ST in the predominantly African American faith-based population of the Washington, …

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Best strategies to recruit and enroll elderly Blacks into clinical and biomedical research

Lennox Graham, Julius S. Ngwa, Oyonumo Ntekim, Oludolapo Ogunlana et autres

Background: Historically, Blacks have been disproportionately underrepresented in clinical trials. Outcomes associated with low Blacks’ participation in research include poor understanding of the predictors and treatment of the disease, increasing health disparities, poor health equity, and suboptimal wellness of the nation as …

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[P4–422]: EXERCISE TRAINING‐INDUCED CHANGES ON DNA METHYLATION IN MILD COGNITIVELY IMPAIRED OLDER AFRICAN AMERICANS: GEMS STUDY

Julius S. Ngwa, Oyonumo Ntekim, Lennox Graham, Joanne Allard et autres

DNA methylation at CpG sites is an important epigenetic modification of the human genome that can affect gene expression and potentially influence health outcomes. Notably, aging and physical exercise have been shown to influence epigenetic modification with during minimal exercise, inducing hypomethylation …

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[P2–527]: NORMATIVE ANALYSIS OF MINI MENTAL STATE EXAMINATION: A CROSS SECTIONAL STUDY IN A PREDOMINANTLY AFRICAN AMERICAN SAMPLE

Julius S. Ngwa, Sharlene Leong, Lennox Graham, Oyonumo Ntekim et autres

Alzheimer's disease, the most common form of dementia, is an emerging public health crisis in African-Americans (AA)s. The incidence among those aged 65 and older is estimated to reach 6.9 million by the year 2030. To improve early diagnosis and treatment, an …

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Abstract MP025: Unfavorable Perceptions of Neighborhood Environment are Associated With Greater Sedentary Time - Data From the Washington, D.C. Cardiovascular Health and Needs Assessment

Chaarushi Ahuja, Colby Ayers, Jacob Hartz, Joel Adu‐Brimpong et autres

Background: Sedentary time (ST) and unfavorable perceptions of neighborhood environment (NE) are independently associated with poor cardiovascular (CV) health. However, little is known about ST’s relationship to NE perceptions. Methods: We examined associations between ST and NE perception in the Washington, DC …

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Adherence with physical activity monitoring wearable devices in a community-based population: observations from the Washington, D.C., Cardiovascular Health and Needs Assessment

Leah Yingling, Valérie Mitchell, Colby Ayers, Marlene Peters‐Lawrence et autres

Wearable mobile health (mHealth) technologies offer approaches for targeting physical activity (PA) in resource-limited, community-based interventions. We sought to explore user characteristics of PA tracking, wearable technology among a community-based population within a health and needs assessment. In 2014–2015, we conducted the …

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