2017
article
OpenAlex
Julius Suh Ngwa, Sharlene Leong, Lennox A. Graham, Oyonumo E. Ntekim et autres
Alzheimer's disease, the most common form of dementia, is an emerging public health crisis in African-Americans (AA)s. The incidence among those aged 65 and older is estimated to reach 6.9 million by the year 2030. To improve early diagnosis and treatment, an …
us
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2016
review
OpenAlex
Charles R. Jonassaint, Victor L. Jones, Sharlene Leong, Georita Marie Frierson
Patients with sickle cell disease (SCD) experience a disproportionately high use of health care resources. Several studies have examined depression and other negative mood states as risk factors for increased health care utilization; however, there have been no systematic reviews examining and …
us
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2016
article
OpenAlex
Suneeta Kumari, Partam Manalai, Sharlene Leong, Alese Wooditch et autres
BACKGROUND AND OBJECTIVES: Opioid use disorders are common, chronic relapsing disorders. Buprenorphine (BUP) is an FDA approved medication in the treatment of opioid use disorders, but patient adherence to this medication remains a challenge. To identify risk factors for non-adherence, this chart …
us
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Accès ouvert
2011
article
OpenAlex
Helene Bach, Victoria Arango, Yung‐yu Huang, Sharlene Leong et autres
BALB/c is an inbred stress-sensitive mouse strain exhibiting low brain serotonin (5-HT) content and a 5-HT biosynthetic enzyme tryptophan hydroxylase (Tph2) variant reported to have lower catalytic activity compared with other inbred base strains. To evaluate other mechanisms that may explain low …
us
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Accès ouvert
1997
article
OpenAlex
Andrew John Brown, Sharlene Leong, Roger Thornton Dean, W. Jessup
7-Hydroperoxycholesterols (7OOHs) are intermediates in cholesterol oxidation and potential cytotoxins. A normal-phase HPLC method with UV (205 nm) detection was developed that could resolve 7 alpha OOH, 7 beta OOH, 7-ketocholesterol (7K), and the epimeric 7-hydroxycholesterols (7OHs). 7OOH formation was investigated when …
au
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1996
article
OpenAlex
Conrad Sernia, Bruce D. Wyse, Siok‐Keen Tey, Sharlene Leong
Angiotensin II (AngII) is the peptide effector hormone of the blood renin-angiotensin system (RAS). Central to the role of the RAS as a hormonal regulator of cardiovascular function are the actions of AngII on vascular tone and on fluid and electrolyte homeostasis …
au
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