The Role of Extracellular Vesicles in the Development and Treatment of Psoriasis: Narrative Review
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Le résumé fourni par la source
Psoriasis is a chronic inflammatory polygenic disease with significant impacts on skin and joints, leading to substantial treatment challenges and healthcare costs. The quest for novel therapeutic avenues has recently highlighted extracellular vesicles (EVs) due to their potential as biomarkers and therapeutic agents in autoimmune diseases, including psoriasis. EVs are nano-sized, lipid membrane-bound particles secreted by cells that have emerged as promising tools for targeted drug delivery, owing to their unique structure. This review delves into how EVs, either as mediators of cell communication or via their cargo (such as miRNA), directly participate in the pathology of psoriasis, influencing processes such as immune regulation, cell proliferation, and differentiation. Furthermore, this review explores the innovative application of EVs in psoriasis treatment, both as direct therapeutic agents and as vehicles for drug delivery, offering a novel approach to overcoming the current treatment limitations.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- The Role of Extracellular Vesicles in the Development and Treatment of Psoriasis: Narrative Review
- Date Crossref
- 12/12/2024
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Guangzhou University of Chinese Medicine Guangdong-Hongkong-Macau Joint Lab on Chinese Medicine and Immune Disease Research pays non établi dans la noticeUniversité ou école supérieure
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The Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine pays non établi dans la noticeUniversité ou école supérieure
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Guangdong Provincial Clinical Medicine Research Center for Chinese Medicine Dermatology pays non établi dans la noticeStructure de recherche
Guangdong-Hongkong-Macau Joint Lab on Chinese Medicine and Immune Disease Research — Guangzhou University of Chinese Medicine, The Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine et Guangdong Provincial Clinical Medicine Research Center for Chinese Medicine Dermatology.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.