Malahat Khalili

Effectiveness and tolerability of pharmacological prophylaxis for migraine headaches: a systematic review and network meta-analysis of randomised controlled trials

Malahat Khalili, Faraidoon Haghdoost, Amin Liaghatdar, Kian Torabiardakani et autres

OBJECTIVES: Migraine headaches are common and potentially disabling disorders, with several interventions available for prevention and symptom reduction. We explored the comparative effectiveness and tolerability of pharmacological prophylaxis for migraine through a network meta-analysis of randomised trials (RCTs). DESIGN: Our study design …

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Effectiveness and Tolerability of Pharmacologic Prophylaxis for Chronic Migraine

Malahat Khalili, Faraidoon Haghdoost, Amin Liaghatdar, Kian Torabiardakani et autres

BACKGROUND: Migraine headaches are considered chronic when they occur on 15 or more days per month. Newer medications are available for prevention. PURPOSE: To explore the effectiveness and tolerability of pharmacologic prophylaxis for chronic migraine. DATA SOURCES: Medline, Embase, Cochrane Central Register …

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Effectiveness and tolerability of pharmacological prophylaxis in migraine patients with prior preventive treatment failure: A systematic review and network meta-analysis of randomized controlled trials

Malahat Khalili, Faraidoon Haghdoost, Amin Liaghatdar, Kian Torabiardakani et autres

BackgroundDespite advances in migraine management, some patients fail to respond to preventive treatments for migraine. We aimed to assess the comparative effects of available pharmacological prophylaxis in adults with a treatment failure history.MethodsWe searched Medline, Embase, Cochrane Central, PsycINFO, Web of Science, …

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Development of risk prediction model for chronic pain after knee replacement surgery: protocol for an individual patient data meta-analysis

Behnam Sadeghirad, Malahat Khalili, Jason W. Busse, Wael Abdelkader et autres

BACKGROUND: Chronic post-surgical pain (CPSP) impacts approximately one in four patients following total knee arthroplasty (TKA) and is associated with reduced function and quality of life. We will conduct a systematic review of prospective studies to identify eligible data and establish an …

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Comparative effectiveness of antidepressants and antipsychotics for management of alcohol use disorder and associated symptoms/comorbidities: a systematic review and network meta-analysis of randomized trials

Behnam Sadeghirad, Malahat Khalili, Tessa Elliot, Veronica Bolis et autres

Alcohol use disorder (AUD) is a chronic, relapsing condition characterized by compulsive alcohol consumption despite negative consequences. It is often associated with mental health comorbidities, including depression, anxiety, and psychotic symptoms, which are frequently managed with antidepressants and antipsychotics. However, the effectiveness …

Comparative effectiveness of antidepressants and antipsychotics for management of opioid use disorder: a systematic review and network meta-analysis of randomized trials

Behnam Sadeghirad, Malahat Khalili, Veronica Bolis, Aidan Loong et autres

Opioid use disorder (OUD) is a chronic, relapsing condition characterized by compulsive substance use despite negative consequences. OUD is associated with significant psychiatric comorbidities, including depression, anxiety, and psychotic symptoms, which are often managed with antidepressant and antipsychotic medications. However, the effectiveness …

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Cannabis consumption and motor vehicle collision: A systematic review and meta-analysis of observational studies

A. Z. Jin, Andrea Darzi, Amne Dargham, Navroop Liddar et autres

BACKGROUND: Increasing legalization of recreational cannabis and availability of cannabinoid products has resulted in expanded use, which is associated with adverse effects including concerns over increased risk of motor vehicle collision (MVC). We aimed to explore the association between cannabis consumption and …

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Management of Amphetamine and Methamphetamine Use Disorders: A Systematic Review and Network Meta-analysis of Randomized Trials

Malahat Khalili, Behnam Sadeghirad, Paxton Bach, Alexis Crabtree et autres

The current evidence regarding effective management of methamphetamine and amphetamine (MA/A) use disorders is inconclusive. Therefore, we assessed the comparative benefits and tolerability of pharmacological, psychosocial, and harm reduction interventions for management of MA/A use disorders. We searched six electronic databases for …

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P.067 Pharmacological prophylaxis for chronic migraine: A systematic review and network meta-analysis of randomized controlled trials

Malahat Khalili, A Liaghatdar, F Mahdian, T Levit et autres

Background: We performed a network meta-analysis of randomized controlled trials to assess the comparative effectiveness of available pharmacological prophylaxis for migraines. Methods: We searched MEDLINE, EMBASE, Web of Science, Scopus, PsycINFO and Cochrane CENTRAL up to October 2023 for trials that: (1) …

ir, ca (code pays fourni par la source)

Systematic review and meta-analysis of maternal mortality ratio and related factors in the Islamic Republic of Iran

Malahat Khalili, Mahdieh Mashrouteh, Ali Akbar Haghdoost, Samaneh Torkian et autres

Background: Maternal mortality is an indication of the health status of women in the society. Aims: To investigate the maternal mortality ratio, causes of maternal mortality, and related risk factors among Iranian women. Methods: Using the Preferred Reporting Items for Systematic Reviews …

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Efficacy and Safety of a Protein-Based SARS-CoV-2 Vaccine

Ehsan Mostafavi, Sana Eybpoosh, Mohammad Karamouzian, Malahat Khalili et autres

Importance: The protein-based SARS-CoV-2 vaccines FINLAY-FR-2 (Soberana 02) and FINLAY-FR-1A (Soberana Plus) showed good safety and immunogenicity in phase 1 and 2 trials, but the clinical efficacy of the vaccine remains unknown. Objective: To evaluate the efficacy and safety of a 2-dose …

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Incidence, accuracy, and barriers of diagnosing healthcare-associated infections: a case study in southeast Iran

Naser Nasiri, Ali Sharifi, Iman Ghasemzadeh, Malahat Khalili et autres

BACKGROUND: Healthcare-associated infections (HAIs) are a threat to patients. Accurate surveillance is required to identify and prevent HAIs. To estimate the incidence rate, report the accuracy and identify the barriers of reporting HAIs using a mixed-method study. METHODS: In this quantitative study, …

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