Wiem Saafi

Idiopathic hirsutism as a normo-androgenic phenotype of polyendocrine metabolic ovarian syndrome: challenging a diagnostic dogma

Taieb Ach, Nadia Ghariani, Wiem Saafi, Imen Bannour et autres

1. Hirsutism affects 5–15% of premenopausal women (1). It constitutes the primary clinical manifestation of hyperandrogenism. Polycystic ovary syndrome (PCOS) has recently been renamed to polyendoc...

Tunisie (code pays fourni par la source)

EP1499 - ECE_3014 - An atypical case of schmidt syndrome in a male without hyperpigmentation

Khadija Had, Hamza El Fekih, Wiem Saafi, Sawsen Nouira et autres

Abstract Introduction Schmidt syndrome is rare autoimmune disease with an estimated prevalence ranging from 1.4 to 4.5 cases per 100 000 inhabitants. It may occur at any age but is uncommon in children and after the age of 60, and it predominantly …

Tunisie (code pays fourni par la source)

EP571 - ECE_2552 - The evolution and management of type V familial hypertriglyceridemia during pregnancy

Fatma Ben Abdessalem, Taieb Ach, Imen Halloul, Wiem Saafi et autres

Abstract Introduction Pregnancy triggers profound metabolic adaptations characterized by hormonal shifts that can increase lipid levels by up to fourfold. While often physiological, this rise poses significant risks for patients with pre-existing dyslipidemia. We present a case of severe hypertriglyceridemia further complicated …

Tunisie (code pays fourni par la source)

EP1156 - ECE_1378 - Value of the LHRH test in the evaluation of precocious puberty

Fatma Ben Abdessalem, Taieb Ach, Imen Halloul, Wiem Saafi et autres

Abstract Introduction Precocious puberty is defined as the appearance of secondary sexual characteristics before age 8 in girls and 9 in boys. The LHRH stimulation test plays a crucial role in identifying the origin of precocious puberty and differentiating true cases from …

Tunisie (code pays fourni par la source)

EP1487 - ECE_2528 - Etiological diagnosis of hypothyroidism after craniofacial radiotherapy

Fatma Ben Abdessalem, Taieb Ach, Imen Halloul, Wiem Saafi et autres

Abstract Introduction Radiotherapy for craniofacial cancers often leads to various forms of thyroid dysfunction as a significant late complication. The aim of this study is to identify the different causes of hypothyroidism following external radiotherapy. Materials and Methods This was a cross-sectional …

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EP835 - ECE_3442 - Allergy to dexamethasone: a rare pitfall in endocrine practice

Rihab Khochtali, Imen Halloul, Taieb Ach, Wiem Saafi et autres

Abstract Background Dexamethasone is widely used in endocrinology, particularly for diagnostic suppression tests. Hypersensitivity reactions to corticosteroids are rare, with a reported frequency ranging from 0.2% to 5%. This condition may represent both a diagnostic and therapeutic challenge. Case Presentation We report …

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EP75 - ECE_2199 - Incidental adrenal angiomyolipoma revealing primary hyperaldosteronism

Hamza El Fekih, Eya Zorai, Wiem Saafi, Sawsen Nouira et autres

Abstract Introduction Angiomyolipoma is an extremely rare mesenchymal tumor without malignant characteristics composed, in varying proportions, of blood vessels, smooth muscle cells, and adipocytes. It usually affects the kidney. Extra-renal angiomyolipoma is rarein clinical practice, particularly in the adrenal glandwhich limits our …

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Assessing the Accuracy of LDL-Cholesterol Estimation Formulas in the Tunisian Population

Oumayma Zarrouk, Hamza Elfekih, Sawssen Mrad, Wiem Saafi et autres

INTRODUCTION: International guidelines for the management of coronary artery disease highlight the importance of LDL-C(low density lipoprotein-cholesterol)measurements in assessing cardiovascular risk and monitoring patients. In clinical practice,its direct measurement is complex and expensive. Therefore,calculating LDL-C using several formulas is simpler and less …

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Cerebral Metastasis in a Fatal Adrenocortical Carcinoma: A Rare Presentation of an Aggressive Tumor

Ach Taieb, Amira Yanes, Rihab Ben Fredj, Majdouline Barkache et autres

Adrenocortical carcinomas (ACCs) are rare, aggressive tumors often discovered incidentally. These malignancies may present with abnormal hormone secretion or, as in some cases, as non-functioning masses causing discomfort. We present a case of brain metastasis in a patient with a giant ACC. …

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New Cortisol Thresholds for the Diagnosis of Adrenal Insufficiency Using the Low-Dose Synacthen Test in Children on Long-Term Corticosteroids: A North African Pilot Study

Taieb Ach, Abdelbari Marwa, Ben Hadj Ali Wiem, Marzouk Hajer et autres

Background: The low-dose Synacthen stimulation test (LD-SST) is the reference dynamic test for diagnosing glucocorticoid-induced adrenal insufficiency (AI) in children, but it is resource-intensive and costly. This study aimed to establish morning cortisol thresholds predictive of hypothalamic–pituitary–adrenal (HPA) axis response to LD-SST …

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Evaluation of HPA Axis Function in Pediatric Patients with Chronic Corticosteroid Therapy Using the Low-Dose (1 μg) Synacthen Test

Wiem Ben Hadj Ali, Marwa Abdelbari, Taieb Ach, Oumayma Zarrouk et autres

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The Diagnostic Challenge of Hypophysitis vs. Non-Functioning Pituitary Macroadenomas: An Updated Review and Comparative Analysis of Distinguishing Criteria

Taieb Ach, Ines Bouzaouech, Ayoub Gasmi, Nassim Ben Haj Slama et autres

Background: Differentiating hypophysitis from non-functioning pituitary macroadenomas (NFPMA) remains a clinical and radiological challenge. Both entities present as sellar masses with overlapping features but require distinct therapeutic approaches. Accurate preoperative identification is necessary to avoid unnecessary surgery in inflammatory forms. This review …

Tunisie (code pays fourni par la source)