EP75 - ECE_2199 - Incidental adrenal angiomyolipoma revealing primary hyperaldosteronism

Le résumé fourni par la source

Abstract Introduction Angiomyolipoma is an extremely rare mesenchymal tumor without malignant characteristics composed, in varying proportions, of blood vessels, smooth muscle cells, and adipocytes. It usually affects the kidney. Extra-renal angiomyolipoma is rarein clinical practice, particularly in the adrenal glandwhich limits our understanding of the disease.We herein report the case of a patient with an incidentally discovered adrenal angiomyolipoma, who was diagnosed with primary hyperaldosteronism during the diagnostic workup. Case Presentation A 58-year-old woman, with grade I arterial hypertension, had an abdominal ultrasoundfor diffuse abdominal pain which revealed a right adrenal mass of 4 cm, with a heterogeneous and hypoechoic appearance. The patient had manysuggestive clinical features of essential hypertension: family history of hypertension, her age, class II obesity, no target organ damage, nor clinical signs suggestive of hormonal hypersecretion. Serum potassiumlevels were normal. Computed tomography scan confirmed the presence of a right adrenal incidentaloma measuring 50 × 32 mm, with radiological features suggesting an angiomyolipoma. Hormonal assessmentwas systematically done confirming primary hyperaldosteronism, with elevated plasma aldosterone levels (561 pmol/L) and aldosterone-to-renin ratio. Discussion Adrenal angiomyolipoma is a rare benign tumor, commonly discovered incidentally during radiological investigations. Although usually considered non-functioning, hormonal hypersecretion may be foundin a few cases of patients with adrenal angiomyolipoma. This association should alert clinicians to the possibility of a potentially curable cause of secondary hypertension requiring specific treatment.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.