Lingting Zeng

NIR‐II‐Photopyroelectric Catalysis for Immunoactivation/Ferroptosis Combined Therapy of Tumor

Chao Xia, Shengqiang Chen, Xishen Xu, Bin Zhao et autres

Abstract Second near‐infrared (NIR‐II) light is desired to drive photocatalytic therapy owing to its high tissue penetrability and operationality, but the efficiency of direct NIR‐II‐photocatalytic H 2 generation is negligible owing to a trade‐off between narrow semiconductor bandgap and high redox potential. …

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NIR‐II‐Photopyroelectric Catalysis for Immunoactivation/Ferroptosis Combined Therapy of Tumor

Chao Xia, Shengqiang Chen, Xishen Xu, Bin Zhao et autres

Abstract Second near‐infrared (NIR‐II) light is desired to drive photocatalytic therapy owing to its high tissue penetrability and operationality, but the efficiency of direct NIR‐II‐photocatalytic H 2 generation is negligible owing to a trade‐off between narrow semiconductor bandgap and high redox potential. …

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Local sustained H2 release assisted stem cell transplantation for enhanced osteoarthritic cartilage regeneration

Shengqiang Chen, An Shao, Chao Xia, Lingting Zeng et autres

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Status quo, challenges and future directions of hydrogen medicine

Shengqiang Chen, Lingting Zeng, Qianjun He

The hydrogen molecule (H 2 ) has distinctive characteristics and advantages in broad-spectrum anti-inflammation, high biosafety and strong tissue permeability, exhibiting therapeutic potential in numerous diseases associated with inflammation and oxidative stress. In this perspective, we attempt to show a clear picture …

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GeSe Nanosheets‐Mediated Local Sonocatalytic Immunosuppression of Rheumatoid Arthritis

Lingting Zeng, Bin Zhao, Danyang Chen, Chao Xia et autres

Abstract The first‐line systemic administration of anti‐rheumatic immunosuppressants unavoidably causes adverse effects such as the increase in the risk of infection. While the emergence of local drug delivery for rheumatoid arthritis (RA) therapy can effectively reduce systemic adverse effects, persistent RA therapy …

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A Slimming/Excavating Strategy for Enhanced Intratumoral Penetration of Acid‐Disassemblable NO‐Releasing Nanomedicines

Lingdong Jiang, An‐Bang Wu, Lingting Zeng, Bin Zhou et autres

Poor tumor penetration is the major predicament of nanomedicines that limits their anticancer efficacy. The dense extracellular matrix (ECM) in the tumor is one of the major barriers against the deep penetration of nanomedicines. In this work, a slimming/excavating strategy is proposed …

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Inhibition of free heme-catalyzed Fenton-like reaction prevents non-alcoholic fatty liver disease by hepatocyte-targeted hydrogen delivery

Min Zhao, Zhaokui Jin, Chao Xia, Shengqiang Chen et autres

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Mesocrystalline ZnS nanoparticles-augmented sonocatalytic full water splitting into H2/O2 for immunoactivating deep tumor

Chao Xia, An‐Bang Wu, Zhaokui Jin, Lingting Zeng et autres

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Sonocatalytic hydrogen/hole-combined therapy for anti-biofilm and infected diabetic wound healing

Qingqing Xu, Shengqiang Chen, Lingdong Jiang, Chao Xia et autres

ABSTRACT It is a great challenge to effectively eradicate biofilm and cure biofilm-infected diseases because dense extracellular polymeric substance matrix prevents routine antibacterial agents from penetrating into biofilm. H2 is an emerging energy-regulating molecule possessing both high biosafety and high tissue permeability. …

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Injectable spontaneous hydrogen-releasing hydrogel for long-lasting alleviation of osteoarthritis

Wenjing Zhang, Lingting Zeng, Huan Yu, Ziheng He et autres

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NIR-photocatalytic regulation of arthritic synovial microenvironment

Bin Zhao, Lingting Zeng, Danyang Chen, Songqing Xie et autres

Synovial microenvironment (SME) plays a vital role in the formation of synovial pannus and the induction of cartilage destruction in arthritis. In this work, a concept of the photocatalytic regulation of SME is proposed for arthritis treatment, and monodispersive hydrogen-doped titanium dioxide …

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Homogeneous Carbon/Potassium‐Incorporation Strategy for Synthesizing Red Polymeric Carbon Nitride Capable of Near‐Infrared Photocatalytic H2 Production

Yangsen Xu, Mingjian Fan, Wenjuan Yang, Yonghao Xiao et autres

Abstract The efficient utilization of near‐infrared (NIR) light for photocatalytic hydrogen generation is vitally important to both solar hydrogen energy and hydrogen medicine, but remains a challenge at present, owing to the strict requirement of the semiconductor for high NIR responsiveness, narrow …

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