Omorefosa O. Osemwegie

Antioxidant properties and computational analysis of bioactive compounds in neem seed methanolic extract as potential anti-inflammatory agents

Marvellous Amarachi Acho, Tomi Lois Olatunji, Gabriel C. Uzoewulu, Omorefosa O. Osemwegie et autres

This study aimed to investigate the antioxidant and anti-inflammatory properties of neem seed methanolic extract (NSME). Antioxidant activity of NSME was investigated using azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging, ferric reducing power, and nitric oxide (NO) scavenging assays, while anti-inflammatory activity was …

Nigéria, Afrique du Sud (code pays fourni par la source)

Leiomyomas: A Review on its Relationships with Transforming Growth Factor–βeta

Mary A. Okesola, Olufemi M. Familua, Charles O. Nwonuma, Marion O. Adebiyi et autres

This study investigates the Transforming Growth FactorBeta (TGF-β)'s role in leiomyoma development. Leiomyomas remain the most common benign tumor traumatizing women especially Black women at the attainment of reproductive age. Reproductive hormones, age, diet lack of vitamin D, are some of the …

An in vivo and in silico predictive study on the toxicological and modulatory effects of abused substances on sperm quality and testicular function in Wistar rats

Charles Obiora Nwonuma, Melody Onyemaka, Emenike Onyebum Irokanulo, Omokolade Oluwaseyi Alejolowo et autres

Introduction: Some compounds like Opioids that are commonly used may affect the biological system in addition to having a high potential for addiction. Objective: This study assessed the effects of commonly misused substances on sperm quality and testicular function in Wistar rats. …

Nigéria (code pays fourni par la source)

Assessment of Biosurfactant Production and Petroleum Hydrocarbons Biodegradation Capability of Actinomycetes Isolated from Soils

Bolanle Adenike Akinsanola, Olusoji Olusegun Adebisi, Omorefosa O. Osemwegie

Production of biosurfactants and emulsifiers by bacteria has been suggested to enhance the biodegradability of hydrocarbons (HCs) in complex matrices like crude oil and its refined products. Recent studies have focused on the capability of actinobacteria to biodegrade HCs because of their …

Nigéria (code pays fourni par la source)

Neem Seed Methanolic Extract Scavenges Free Radicals and Demonstrate Bacterial Growth Inhibition Potential

Omorefosa O. Osemwegie, Marvellous Amarachi Acho, Charles Obiora Nwonuma, Rachel I. Udoh et autres

This study aimed to assess the free radical scavenging activity antibacterial and bacterial growth inhibitory potential of the Azadirachta indica (neem) seed methanolic extract (NSME). NSME was subjected to phytochemical screening and the antioxidant activity was assayed by determining the 2-diphenyl-1-picrylhydrazil (DPPH) …

Nigéria (code pays fourni par la source)

Possible Methods of Suppressing Mycotoxin in Aquatic Organisms Feed

A.I. Ilesanmi, M. I. Adeoba, O. A. Bubu-Davies, Omorefosa O. Osemwegie et autres

Nigéria, Afrique du Sud (code pays fourni par la source)

Toxicological assessment of ZnO-Vernonia amygdalina nanoparticle-treated Asa River water in albino rats

Rotimi Olusanya Arise, Ayokunmi Akinduko, Oluwasegun S. Maccarthy, Titilayo M. Olurombi et autres

Traditional water purification methods are increasingly inadequate, leading to the exploration of novel approaches. This study investigated the application of plant-derived nanomaterials for heterogeneous photocatalytic water treatment using ZnO-Vernonia amygdalina nanoparticles (ZVAN). The study evaluated the efficacy of ZVAN in purifying Asa …

Nigéria (code pays fourni par la source)

Assessment of the anxiolytic, antidepressant, and antioxidant potential of Parquetina nigrescens (Afzel.) Bullock in Wistar rats

Ayokunmi Akinduko, Sule Ola Salawu, Afolabi Clement Akinmoladun, Afolabi Akintunde Akindahunsi et autres

ETHNOPHARMACOLOGICAL RELEVANCE: The recent growing concerns about the multisystemic nature of mental health conditions in the global population are facilitating a new paradigm involving alternative natural, nutritional, and complementary therapies. Herbal remedies despite accounts in literature of their ethnobotanical as alternative remedies …

Nigéria (code pays fourni par la source)

Application and Acceptability of Microbiomes in the Production Process of Nigerian Indigenous Foods: Drive towards Responsible Production and Consumption

Abiola Folakemi Olaniran, Omorefosa O. Osemwegie, Abiola Ezekiel Taiwo, Clinton Emeka Okonkwo et autres

In Nigeria, the use of microorganisms for food product modulation, development, and commercialization through biotechnological innovations remains unexplored and unaccepted. The microbiome-based sustainable innovation in the production process of Nigerian indigenous food requires a vigorous drive toward responsible consumption and production. The …

Nigéria, Afrique du Sud, ae (code pays fourni par la source)

Physico-chemical and functional characteristics of neem seed protein isolate

Marvellous Amarachi Acho, Omorefosa O. Osemwegie, Eric Oscar Amonsou, Rotimi Olusanya Arise

The demands for plant-based proteins have increased, hence, the search for alternative sources for beneficial purposes. The physico-chemical and functional characteristics of protein isolated from neem seed were ascertained in this work. Neem seed protein isolate (NSPI) contained 86.33% protein rich in …

Nigéria, Afrique du Sud (code pays fourni par la source)

Growth promotion and protective potentials of leaf infusions of Parkia biglobosa, Moringa oleifera and Vernonia amygdalina on Abelmoschus esculentus seeds

Oghenerobor B. Akpor, Marvellous-Mercy Maxwell, Ikponmwosa Owen Evbuomwan, Tomilola Debby Olaolu et autres

The germinability and protective potential of leaf infusion of Parkia biglobosa, Moringa oleifera and Vernonia amygdalina leaves on okra (Abelmoschus esculentus) seeds against infections simulated with suspended cells of Aspergillus niger, A. flavus, A. fumigatus, and Penicillium sp. were examined. Prior to …

Nigéria (code pays fourni par la source)

Antidiabetic Activity of Elephant Grass (Cenchrus Purpureus (Schumach.) Morrone) via Activation of PI3K/AkT Signaling Pathway, Oxidative Stress Inhibition, and Apoptosis in Wistar Rats

Oluwafemi Adeleke Ojo, Abosede Itunuoluwa Oni, Susan Grant, Jennifer Chidubem Amanze et autres

Ethnopharmacological Relevance: The management of diabetes over the years has involved the use of herbal plants, which are now attracting interest. We assessed the antidiabetic properties of aqueous extract of C. purpureus shoots (AECPS) and the mechanism of action on pancreatic ß …

Nigéria, sa, Égypte (code pays fourni par la source)