Satoko Takemoto

Physical basis of platelet glycoprotein Ibα binding with von Willebrand factor and with coagulant factor XI on their biological functions

Masamitsu Nakayama, Satoko Takemoto, Shinichi Goto, Shinichi Goto et autres

jp (code pays fourni par la source)

Pan-cancer analysis of RNA expression signatures associated with cancer tissue architecture

Megumi Mogi, Katsushige Kawase, Hiroyoshi Tanaka, S. Miyata et autres

jp (code pays fourni par la source)

Computer-aided demarcation of early gastric cancer: a pilot comparative study with endoscopists

Satoko Takemoto, Keisuke Hori, Yoshimasa Sakai, Masaomi Nishimura et autres

jp (code pays fourni par la source)

Different Physical Parameters in the Bonds between Platelet Glycoprotein Ibalpha with von Willebrand factor and with Coagulant Factor XI -Results from the Molecular Dynamic Simulation-

Masamitsu Nakayama, Shinichi Goto, Satoko Takemoto, Hideki Oka et autres

Background: Both von Willebrand factor (VWF) and coagulation factor XI (FXI) bind with platelet membrane glycoprotein (GP) Ibalpha. However, the differences in the physical parameters in the bonds between VWF-GPIbalpha and FXI-GPIbalpha mediating different biological functions are unclear. Methods: The FXI molecule …

jp, us (code pays fourni par la source)

A covalently linked probe to monitor local membrane properties surrounding plasma membrane proteins

Miwa Umebayashi, Satoko Takemoto, Luc Reymond, Mayya Sundukova et autres

Functional membrane proteins in the plasma membrane are suggested to have specific membrane environments that play important roles to maintain and regulate their function. However, the local membrane environments of membrane proteins remain largely unexplored due to the lack of available techniques. …

ch, jp, es, it, de (code pays fourni par la source)

Author Reply to Peer Reviews of Receptor-linked environment-sensitive probe monitors the local membrane environment surrounding the insulin receptor

Howard Riezman, Kai Johnsson, Hideo Yokota, Paul A. Heppenstall et autres

Detecting colon polyps in endoscopic images using artificial intelligence constructed with automated collection of annotated images from an endoscopy reporting system

Keisuke Hori, Hiroaki Ikematsu, Yoichi Yamamoto, Hiroki Matsuzaki et autres

BACKGROUND: Artificial intelligence (AI) has made considerable progress in image recognition, especially in the analysis of endoscopic images. The availability of large-scale annotated datasets has contributed to the recent progress in this field. Datasets of high-quality annotated endoscopic images are widely available, …

jp (code pays fourni par la source)

Morphology and function analyses of cell population using image processing

Satoko Takemoto, S. Yoshizawa, Norio Yamashita, Masahiko Morita et autres

近年のイメージング技術の発展によって、これまでは見ることができなかったさまざまな生命現象を、ナノスケールの精度で観察できるようになってきた。だが同時に、観察画像は大規模で複雑なものとなり、現象の理解に有用な情報を取り出すための画像解析の専門性は年々高くなっている。画像解析には汎用画像処理ソフトウェアで利用できるような古典的な信号処理フィルタや、機械学習に基づく注目領域の抽出などの幅広い技術があり、さまざまな解析目的に応じて処理法を取捨選択する必要がある。本稿では最新のイメージング技術によって取得した細胞集団や細胞内現象の観察画像に対して、筆者らや共同研究者らがこれまでに行ったノイズ除去、細胞集団および細胞内骨格の動態解析、細胞膜周辺領域と細胞分裂の検出に関する画像解析法とその周辺技術を紹介する。

jp (code pays fourni par la source)

Accurate and fast mitotic detection using an anchor-free method based on full-scale connection with recurrent deep layer aggregation in 4D microscopy images

Titinunt Kitrungrotsakul, Yutaro Iwamoto, Satoko Takemoto, Hideo Yokota et autres

BACKGROUND: To effectively detect and investigate various cell-related diseases, it is essential to understand cell behaviour. The ability to detection mitotic cells is a fundamental step in diagnosing cell-related diseases. Convolutional neural networks (CNNs) have been successfully applied to object detection tasks, …

jp, cn (code pays fourni par la source)

Receptor-linked environment-sensitive probe monitors the local membrane environment surrounding the insulin receptor

Miwa Umebayashi, Satoko Takemoto, Luc Reymond, Mayya Sundukova et autres

Abstract Functional membrane proteins in the plasma membrane are suggested to have specific membrane environments that play important roles to maintain and regulate the function of proteins. However, the local membrane environments of membrane proteins remain largely unexplored due to the lack …

ch, jp, it, de (code pays fourni par la source)

Applying Convolutional Neural Networks for Automatic Detection of Early Gastric Cancer with Limited Endoscopic Images

Satoko Takemoto, Keisuke Hori, Yoshimasa Sakai, Masaomi Nishimura et autres

原稿受付 令和元年 7 月 1 日 ** 正 会 員 国立研究開発法人理化学研究所(埼玉県和光市広沢 2-1) *** 国立研究開発法人国立がん研究センター東病院(千葉県柏市柏の葉 6-5-1) 国立研究開発法人理化学研究所(埼玉県和光市広沢 2-1) 国立研究開発法人国立がん研究センター 先端医療開発センター(千葉県柏 市柏の葉 6-5-1)

An end-to-end CNN and LSTM network with 3D anchors for mitotic cell detection in 4D microscopic images and its parallel implementation on multiple GPUs

Titinunt Kitrungrotsakul, Xian‐Hua Han, Yutaro Iwamoto, Satoko Takemoto et autres

jp, sg, cn (code pays fourni par la source)