Vadim P. Mikhin

Remodeling of the major arteries of the brain and serum cystatin C levels in patients with non-communicable diseases

Ilkhom T. Murkamilov, К. А. Айтбаев, Victor V. Fomin, J. A. Murkamilova et autres

Objective. To evaluate serum cystatin C concentrations and the remodeling of major arteries in patients with non-communicable diseases (NCDs). Material and methods. A total of 460 patients diagnosed with NCDs participated in the study, including 229 (49.8%) males and 231 (50.2%) females, …

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Resolution of the expert council «Possibilities of neuroprotective therapy in patients with arterial hypertension and cognitive disorders»

Martynov Ai, Marine Movsesovna Tanashyan, Andrey G. Malyavin, Anna Nicolaevna Bogolepova et autres

On November 20, 2023 in Moscow under the auspices of the All-Russian Public Organization “Russian Scientific Medical Society of Therapists” (RNMOT) a meeting of the Council of Experts was held on the topical issues of the impact of arterial hypertension (AH) on …

Possibilities of using cytoprotectors in complex therapy of chronic coronary heart disease

Vadim P. Mikhin, N. Yu. Borovkova, A.V. Shulyndin

The chronic form of coronary heart disease (CHD) is one of the most common types of cardiovascular pathology in the Russian Federation. The main causes of myocardial ischemia are a decrease in coronary reserve, as well as a decrease in coronary blood …

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The possibilities of Mexidol in the complex therapy of arterial hypertension

Vadim P. Mikhin, Н В Костина, Tamara A. Nikolenko, Marina A. Chernyatina

A review of the literature is devoted to the effects of the ethylmethylhydroxypyridine succinate (mexidol) in patients with arterial hypertension. The analysis of 44 sources of Russian and foreign literature showed more effective achievement of the target values of blood pressure, prevention …

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Heart rate variability in patients with acute ST-segment elevation myocardial infarction after COVID-19

Vadim P. Mikhin, Olga A. Osipova, Anna I. Gindler, A. S. Brizhaneva et autres

Aim. To compare heart rate variability parameters in patients after a coronavirus disease 2019 (COVID-19) with acute ST elevation myocardial infarction (STEMI) during the inhospital and post-hospital periods. Material and methods. A total of 140 patients with STEMI were divided into 2 …

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Features of intracardiac hemodynamics in patients with acute myocardial infarction with st segment elevation who underwent COVID-19

Vadim P. Mikhin, Anna I. Gindler, Natal'ya Viktorovna Zaikina, Margarita P. Zaikina et autres

Objective: to evaluate the features of central and intracardiac hemodynamics in patients with ST-segment elevation myocardial infarction (STEMI), who underwent COVID-19 during inpatient stay and 6 months after the development of STEMI. Materials and methods. 140 patients with STEMI were included in …

Features of cardiac arrhythmias in patients with acute st-segment elevation myocardial infarction who underwent COVID-19

Vadim P. Mikhin, Anna I. Gindler, Natal'ya Viktorovna Zaikina, Margarita P. Zaikina et autres

Objective: to conduct a comparative assessment of the parameters of heart rhythm and conduction in patients with Covid-19 with acute ST-segment elevation myocardial infarction (STEMI) in the hospital and post-hospital treatment periods. Materials and methods. The study included 140 patients with STEMI, …

Content of matrix metalloproteinases in the blood of hypertensive patients with a high cardiovascular risk receiving statin therapy

Vadim P. Mikhin, Olga A. Osipova, V. V. Vorotyntseva, D. N. Perutsky et autres

Aim. To compare the effect of atorvastatin and rosuvastatin as part of complex therapy in patients with hypertension (HTN) with a high cardiovascular risk on the level of matrix metalloproteinases -1, -9 (MMP-1, MMP-9) and tissue inhibitors of metalloproteinases -1, -4 (TIMP-1, …

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Advantages of long-term combination pharmacotherapy with a beta-blocker and eplerenone in patients with ST-segment elevation acute coronary syndrome

Olga A. Osipova, Vadim P. Mikhin, A. I. Golovin, О. Н. Белоусова et autres

Aim.To conduct a comparative analysis of the effect of long-term pharmacotherapy (12 months) using a β-blocker (nebivolol) and its combination with eplerenone in patients after ST-segment elevation acute coronary syndrome (STE-ACS) with heart failure with mildly reduced ejection fraction (EF) (HFmrEF) on …

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Patients with a Combination of Atrial Fibrillation and Chronic Heart Failure in Clinical Practice: Comorbidities, Drug Treatment and Outcomes

M. M. Loukianov, S. Yu. Martsevich, Yu. V. Mareev, S. S. Yakushin et autres

Aim. To assess in clinical practice the structure of multimorbidity, cardiovascular pharmacotherapy and outcomes in patients with a combination of atrial fibrillation (AF) and chronic heart failure (CHF) based on prospective registries of patients with cardiovascular diseases (CVD). Materials and Methods. The …

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The level of matrix metalloproteinase type 12 in the blood of arterial hypertension patients with high cardiovascular risk on the background of statin therapy

Vadim P. Mikhin, V. V. Vorotyntseva, Tamara A. Nikolenko, Valentina V. Savelyeva et autres

Objective: to evaluate the features of changes in the content of metalloproteinase-12 (MMR-12) in blood serum in patients with arterial hypertension (AH) of high cardiovascular risk (SSR) against the background of therapy with atorvastatin (20 mg/day) or rosuvastatin (10 mg/day; 20 mg/day; …

Change in the value of the QT interval at various stages of the perioperative period in patients with coronary ischemic heart disease under general anesthesia

Vadim P. Mikhin, Sergey A. Sumin, Н. А. Волкова, Elena N. Bogoslovskaya et autres

Objective. To evaluate the status of QT interval derivatives in patients with chronic IHD during different perioperative periods of planned open cholecystectomy under general anaesthesia and to determine the possibility of using meldonium for prevention of QT interval dysfunction. Materials and methods. …

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