Una Martin

Clinical implementation of a hybrid solitary dynamic portal radiotherapy for left-sided post-mastectomy chest-wall and regional nodal irradiation using Monaco TPS

K Mohamathu Rafic, Md. Akhtaruzzaman, Una Martin, S K Mounageetha et autres

A hybrid solitary dynamic portal radiotherapy (h-SDPRT) technique for complex chest-wall and regional nodal irradiation was clinically implemented on the Monaco treatment planning system (TPS) by effectively adapting the Eclipse-based h-SDPRT method with minimal amendments to align with Monaco-specific technical constraints while …

in (code pays fourni par la source)

Arm Based on LEg blood pressures (ABLE-BP): can systolic ankle blood pressure measurements predict systolic arm blood pressure? An individual participant data meta-analysis from the INTERPRESS-IPD Collaboration

Sinéad T. J. McDonagh, Fiona C Warren, James Peter Sheppard, Kate Boddy et autres

OBJECTIVES: To determine associations between arm and ankle systolic blood pressures (SBPs), develop and validate a multivariable model predicting arm SBP from ankle SBP, and investigate associations between ankle SBP, cardiovascular disease and mortality. DESIGN: Ankle-arm SBP differences were examined in two-stage …

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Sodium valproate, a potential repurposed treatment for the neurodegeneration in Wolfram syndrome (TREATWOLFRAM): trial protocol for a pivotal multicentre, randomised double-blind controlled trial

Renuka Dias, Kristian Brock, Kun Hu, Rajat Gupta et autres

Introduction Wolfram syndrome ( WFS1- Spectrum Disorder) is an ultra-rare monogenic form of progressive neurodegeneration and diabetes mellitus. In common with most rare diseases, there are no therapies to slow or stop disease progression. Sodium valproate, an anticonvulsant with neuroprotective properties, is …

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ARM BASED ON LEG BLOOD PRESSURES (ABLE-BP): CAN SYSTOLIC LEG BLOOD PRESSURE MEASUREMENTS PREDICT BRACHIAL BLOOD PRESSURE? AN INDIVIDUAL PARTICIPANT DATA META-ANALYSIS

Sinéad T. J. McDonagh, James Peter Sheppard, Fiona C Warren, Kate Boddy et autres

Objective: Hypertension is diagnosed and managed using brachial blood pressures; accurate measurement can be impeded by several temporary or permanent factors, including fractures, presence of vascular access devices, limb deformities and altered muscle tone after stroke. Leg (ankle) blood pressure measurement is …

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Measuring adherence to antihypertensive medication using an objective test in older adults attending primary care: cross-sectional study

James Peter Sheppard, Ali Albasri, Pankaj Gupta, Prashanth Patel et autres

Analysis of urine samples using liquid chromatography-tandem mass spectrometry (LC-MS/MS) has previously revealed high rates of non-adherence to antihypertensive medication. It is unclear whether these rates represent those in the general population. This study aimed to investigate whether it is feasible to …

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ARM BASED ON LEG BLOOD PRESSURES (ABLE-BP): CAN LEG BLOOD PRESSURE MEASUREMENTS PREDICT BRACHIAL BLOOD PRESSURE? INDIVIDUAL PARTICIPANT DATA META-ANALYSIS FROM THE INTERPRESS-IPD

Sinéad T. J. McDonagh, James Peter Sheppard, Fiona C Warren, Kate Boddy et autres

Objective: Hypertension, a key modifiable risk factor for prevention of stroke, is diagnosed and managed using upper arm blood pressure (BP) measurement. Amputations, altered muscle tone or limb deformities can prevent accurate brachial BP measurement and cardiovascular risk estimation, thus placing a …

gb, us (code pays fourni par la source)

P005 Rheumatology virtual clinics during COVID-19: are our patients satisfied?

Fajer A Altamimi, Una Martin

Abstract Background/Aims Telemedicine can be broadly defined as the use of telecommunication technologies to provide medical information and services. It can be audio, visual, or text. Its use has increased dramatically during the COVID-19 pandemic to ensure patient and healthcare worker safety. …

Arm Based on LEg blood pressures (ABLE-BP): can systolic leg blood pressure measurements predict systolic brachial blood pressure? Protocol for an individual participant data meta-analysis from the INTERPRESS-IPD Collaboration

Sinéad T. J. McDonagh, James Peter Sheppard, Fiona C Warren, Kate Boddy et autres

INTRODUCTION: Blood pressure (BP) is normally measured on the upper arm, and guidelines for the diagnosis and treatment of high BP are based on such measurements. Leg BP measurement can be an alternative when brachial BP measurement is impractical, due to injury …

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COVID-19 and hypertension: risks and management. A scientific statement on behalf of the British and Irish Hypertension Society

Christopher Elles Clark, Sinéad T. J. McDonagh, Richard J. McManus, Una Martin

Hypertension is the single largest global contributor to disability-adjusted life years lost [ 1 ]. The majority of the population aged over 60 years have hypertension [ 2 ], and it has been suggested that they may be at increased risk from …

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Measurement of blood pressure in the leg—a statement on behalf of the British and Irish Hypertension Society

James Peter Sheppard, Peter S Lacy, Philip Lewis, Una Martin

Ankle blood pressure (BP) measurement is necessary for the diagnosis of hypertension where measurements are not possible due to medical conditions or limb deformities. Based on a recent review of the evidence, we recommend an ankle BP threshold of ≥155/90 mmHg to …

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Nonadherence to antihypertensive medications is related to pill burden in apparent treatment-resistant hypertensive individuals

Alexander J. Lawson, Mohammed Awais Hameed, Roger Brown, Francesco Paolo Cappuccio et autres

OBJECTIVE: Nonadherence to medication is present in at least 50% of patients with apparent treatment-resistant hypertension. We examined the factors associated with nonadherence as detected by a liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based urine antihypertensive drug assay. METHODS: All urine antihypertensive test results, …

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Correction: Oscillometric measurement of blood pressure: a simplified explanation. A technical note on behalf of the British and Irish Hypertension Society (Journal of Human Hypertension, (2019), 33, 5, (349-351), 10.1038/s41371-019-0196-9)

Paul S. Lewis, Niamh Chapman, Phil Chowienczyk, C. J. CLARK et autres