Kun Hu

Electrocoagulation therapy for a patient with an acute thalamoperforating artery pseudoaneurysm: a case report

Xiaoping Zhou, Guanlin Huang, Mingang Zou, Kun Hu et autres

BACKGROUND: Thalamoperforating artery (TPA) pseudoaneurysms are relatively uncommon and often pose significant challenges in detection through vascular examination. Furthermore, their management, particularly via endovascular therapy, is complex and demanding. This article presents a case study of a patient diagnosed with an acute …

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Semaglutide as an add-on treatment to optimise glycaemic control in children and young people with type 1 diabetes (smile T1D trial) development and protocol

Kun Hu, Sheriden Bevan, William McKinnon, Eleni Gkini et autres

Adjunctive glucose-lowering agents in children with type 1 diabetes: a systematic review and meta-analysis

Kun Hu, Sophie Beese, David Moore, Andrew Gan et autres

Exploring the medication rules of national TCM master WANG Qi in treating bronchial asthma based on data mining

Han MA, Kun Hu, Ji Wang

目的 挖掘王琦院士治疗支气管哮喘的用药规律，拓宽治疗支气管哮喘的临床诊疗思路，为中医治疗支气管哮喘提供临床依据和参考。 方法 采集并整理王琦院士门诊治疗支气管哮喘的完整医案，使用Excel 2019建立治疗支气管哮喘的方药数据库，运用SPSS Modeler 18.0、SPSS Statistics 26.0、Gephi 0.10.1软件进行频次统计、关联规则、聚类分析及数据可视化，然后运用中医学理论对统计结果进行分析讨论。 结果 纳入治疗支气管哮喘的处方546首，涉及中药195味，总用药频次为6564次。常用中药为乌梅、蝉蜕、灵芝、甘草、苦杏仁等，以解表药、清热药和补虚药为主，药性以平为主，药味多甘辛苦，归经多属肺经、肝经、脾经。挖掘得到关联规则20条（2味药14条、3味药6条），包括“防风-乌梅”“石膏-乌梅”“麻黄-乌梅”“苦杏仁-乌梅”等。聚类分析得到5类药物，包括“乌梅、蝉蜕、灵芝、防风”“麻黄、石膏、苦杏仁、甘草”等多种药物组合。主成分因子分析共提取出6个公因子，包括“麻黄、苦杏仁、石膏、甘草”“乌梅、蝉蜕、灵芝”等。 结论 王琦院士临证辨治支气管哮喘重视“调体抗过敏和宣肺泄热平喘”相结合，强调解表药与清热药的配合应用，提出“辨体-辨病-辨证”相结合辨治支气管哮喘的新思路。

Glucagon-like peptide-1 (GLP-1) receptor agonists: applications in childhood diabetes and obesity

Kun Hu, Timothy Barrett

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Sodium valproate, a potential repurposed treatment for the neurodegeneration in Wolfram syndrome (TREATWOLFRAM): trial protocol for a pivotal multicentre, randomised double-blind controlled trial

Renuka Dias, Kristian Brock, Kun Hu, Rajat Gupta et autres

Introduction Wolfram syndrome ( WFS1- Spectrum Disorder) is an ultra-rare monogenic form of progressive neurodegeneration and diabetes mellitus. In common with most rare diseases, there are no therapies to slow or stop disease progression. Sodium valproate, an anticonvulsant with neuroprotective properties, is …

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Electrocoagulation treatment for patient with acute thalamoperforating artery pseudoaneurysm：a case report

Xiaoping Zhou, Guanlin Huang, Mingang Zou, Kun Hu et autres

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Research Progress of Glucose Sensor Suitable for 3D Printing

Kun Hu, Linxinzheng Guo, Haibo Wang, Jundong Wang et autres

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WFS1 protein expression correlates with clinical progression of optic atrophy in patients with Wolfram syndrome

Kun Hu, Malgorzata Zatyka, Dewi Astuti, Nicola L. Beer et autres

Background Wolfram syndrome (WFS) is a rare disorder characterised by childhood-onset diabetes mellitus and progressive optic atrophy. Most patients have variants in the WFS1 gene. We undertook functional studies of WFS1 variants and correlated these with WFS1 protein expression and phenotype. Methods …

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Advances in Research on Sustained-Release Chlorine Dioxide Solid Preparations

Weiwei Sun, Kun Hu, Haibo Wang, Jundong Wang et autres

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Observed effects of growth hormone doses on height in patients with Prader Willi Syndrome

Kun Hu, Ruth Krone, Rebecca Follows, David Marks et autres

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Bioinformatics Study on Differential Expression Profiles of Qi Stagnation and Blood Stasis Syndrome Based on Literature

Haoqiang He, Guang Chen, Jialiang Gao, Kun Hu et autres