Neale Wiley

Improvements in ultra-low field portable MRI and applications for global neurology

Anthony Traboulsee, Sharada Balaji, Augustine Rosati, Neale Wiley et autres

ca, us, gb (code pays fourni par la source)

Quantifying longitudinal tract profile differences in multiple sclerosis lesional tracts

Adrian Wu, Anthony Traboulsee, David Li, Roger Tam et autres

Motivation: Region-of-interest analyses of quantitative MRI measures may overlook heterogeneity in tissue microstructure. Tract profiling shows greater detail but is difficult to quantify over time. Goal(s): Quantify differences in lesional tract profiles across two timepoints. Approach: Tract profiles associated with focal lesions …

Undercooked PASTA: Tractometry at low field and low SAR

James Gholam, Joshua Ametepe, Neale Wiley, Shannon Kolind et autres

Motivation: Tractography affords advantage over volumetric segmentation as it separates areas of otherwise homogeneous contrast based on microstructural measures. Tract-based parameter mapping performed at ultra-low-field extends the utility of parametric maps to isolate functional regions, permitting quantitative studies in otherwise unscanned populations …

Myelin water imaging from an 8 minute scan at 64mT via image reconstruction and multicomponent T2 fitting in a low-rank space

Neale Wiley, Sharada Balaji, Megan Poorman, Rui Teixeira et autres

Motivation: Ultra-low field (ULF) MRI scanners are proliferating and their use to measure brain health through myelin content would benefit clinical applications and research. Goal(s): To leverage low-rank algorithms to achieve quantitative measurements of brain myelin content at ULF. Approach: Following low-rank …

Myelin water and tensor‐valued diffusion imaging: (How) are they related?

Sharada Balaji, Adam Dvorak, Neale Wiley, Erin L. MacMillan et autres

Abstract Purpose Conventional MRI offers limited insight into specific characteristics of central nervous system tissue, whereas quantitative MRI measures can provide more detailed information about different aspects of microstructure. A multi‐metric approach involving multiple quantitative measures may improve our understanding of healthy …

ca (code pays fourni par la source)

Magnetization transfer imaging using non‐balanced SSFP at ultra‐low field

Sharada Balaji, Neale Wiley, Adam Dvorak, Francesco Padormo et autres

PURPOSE: Ultra-low field MRI scanners have the potential to improve health care delivery, both through improved access in areas where there are few MRI scanners and allowing more frequent monitoring of disease progression and treatment response. This may be particularly true in …

ca, gb, us, se (code pays fourni par la source)

UPsampling by Subspace Informed ZEro-padded Reconstruction (UPSIZER) in Diffusion Tensor Imaging

Neale Wiley, Sharada Balaji, Adam Dvorak, Irene M. Vavasour et autres

Motivation: Diffusion tensor imaging (DTI) is inherently resolution limited by MRI gradient performance and human tolerance of gradient slew rates but could benefit greatly from finer detail for tissue mapping. Goal(s): To increase the resolution of DTI images by using the joint …

Reproducibility of quantitative MRI measures at Ultra-Low Field

Sharada Balaji, Neale Wiley, Adam Dvorak, Francesco Padormo et autres

Motivation: Ultra-low field scanners can vastly improve access to neuroimaging, and implementing MRI techniques to quantify microstructure allows monitoring of both neurodegenerative diseases as well as myelination trajectories during development. Goal(s): To assess the reliability of microstructure-sensitive methods at ultra-low field before …

UNITY: A low-field magnetic resonance neuroimaging initiative to characterize neurodevelopment in low and middle-income settings

Amanda Adu-Amankwah, KA Ae-Ngibise, Francis Agbokey, VA Agyemang et autres

Measures of physical growth, such as weight and height have long been the predominant outcomes for monitoring child health and evaluating interventional outcomes in public health studies, including those that may impact neurodevelopment. While physical growth generally reflects overall health and nutritional …

Éthiopie, Ghana, us, gb, ca, Afrique du Sud, no, Kenya, Ouganda, bd, pk, Zambie, in, nl, se, Malawi, de, au (code pays fourni par la source)

Low-field MRI for use in neurological diseases

Sharada Balaji, Neale Wiley, Megan Poorman, Shannon Kolind

PURPOSE OF REVIEW: To review recent clinical uses of low-field magnetic resonance imaging (MRI) to guide incorporation into neurological practice. RECENT FINDINGS: Use of low-field MRI has been demonstrated in applications including tumours, vascular pathologies, multiple sclerosis, brain injury, and paediatrics. Safety, …

ca (code pays fourni par la source)

The CALIPR framework for highly accelerated myelin water imaging with improved precision and sensitivity

Adam Dvorak, Dushyant Kumar, Jing Zhang, Guillaume Gilbert et autres

Quantitative magnetic resonance imaging (MRI) techniques are powerful tools for the study of human tissue, but, in practice, their utility has been limited by lengthy acquisition times. Here, we introduce the Constrained, Adaptive, Low-dimensional, Intrinsically Precise Reconstruction (CALIPR) framework in the context …

ca, us, es (code pays fourni par la source)

Making myelin water imaging “normal”: Robust acquisition for cervical cord with low peripheral nerve stimulation

Sharada Balaji, Adam Dvorak, Neale Wiley, Laura Barlow et autres

The standard myelin water imaging (MWI) sequence for cervical spinal cord, 3D gradient and spin echo (GRASE), was modified to allow scanning in “normal mode” (limiting imaging parameters that may cause physiologic stress) for patients who may not tolerate peripheral nerve stimulation …