Wei‐Chih Chen

Reframing Head and Neck Cancer Costs—Insights from Screening in Taiwan

Ching‐Nung Wu, Wei‐Chih Chen, Sheng‐Dean Luo

To the Editor Villemure-Poliquin et al1 identify stage and multimodality treatment as the strongest factors associated with high first-year costs in head and neck cancer. We commend the population-based approach, but 3 issues merit clarification and qualification.

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Post-traumatic stress disorder among family members of patients with prolonged mechanical ventilation

Wei‐Chih Chen, Chia-Fen Tsai, Kuang‐Yao Yang

Background: The incidence and risk factors contributing to post-traumatic stress disorder (PTSD) symptoms in family members of patients undergoing prolonged mechanical ventilation (PMV) remain unclear. This study aims to investigate the prevalence of PTSD symptoms and associated factors in family members of …

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Bone morphogenetic protein 10 serves as a biomarker and a potential therapeutic target for endothelial dysfunction in endotoxin-induced acute lung injury

Wen-Kuang Yu, Wei‐Chih Chen, Hsiao‐Chin Shen, Chuan-Yen Sun et autres

BACKGROUND: Endothelial dysfunction plays a crucial role in the development of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) in critically ill patients. Bone Morphogenetic Protein 10 (BMP10) has been demonstrated to promote cardiovascular development and cell proliferation, support endothelial …

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Insights on Distress Measurement in Head and Neck Cancer

Ching‐Nung Wu, Wei‐Chih Chen, Sheng‐Dean Luo

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Cetuximab and immune checkpoint inhibitors treatments in recurrent/metastatic head and neck squamous cell carcinoma

Yuming Wang, Sheng‐Dean Luo, Ching‐Nung Wu, Shao‐Chun Wu et autres

Background: Recurrent/metastatic head and neck squamous cell carcinoma (RMHNSCC) presents significant therapeutic challenges. While cetuximab (EGFR inhibitor) and immune checkpoint inhibitors (ICIs) have improved outcomes, optimal treatment sequencing remains undefined. Methods: This retrospective analysis evaluated 822 RMHNSCC patients treated between January 2016 …

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UCle-Compliant Chiplet Interconnect Design Leveraging Cutting-Edge Packaging Technologies

Yu‐Jie Huang, Mu-Shan Lin, Chien-Chun Tsai, Wei‐Chih Chen et autres

UCle is a new chiplet interconnect standard offering superior bandwidth density and interoperability. This paper provides a comprehensive exploration of UCle interconnect design, focusing on four essential aspects: interface circuit architecture, floorplan strategies, package-level channel optimization, and power delivery network (PDN) analysis. …

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Early fungal colonization and infection as an independent predictor of in-hospital mortality in mechanically ventilated COVID-19 patients: A nationwide target trial emulation study in Taiwan

Yao-Kuang Wu, Hsueh-Wen Chung, Wei‐Chih Chen, Kuang‐Yao Yang et autres

To evaluate the impact of fungal colonization and infection phenotypes and other prognostic factors on in-hospital mortality among mechanically ventilated COVID-19 patients (n = 376) admitted to ICUs during the first wave of the pandemic in Taiwan. A target trial emulation framework …

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Light Control of Triplet Pairing in Correlated Electrons with Mixed-Sign Interactions

Zecheng Shen, Chen Xie, Wei‐Chih Chen, Yao Wang

Spin-triplet superconductivity is a key platform for topological quantum computing, yet its experimental realization and control in solid-state materials remain a significant challenge. For this purpose, we propose an ultrafast optical strategy to manipulate spin-triplet superconductivity by leveraging $p$-wave pairing instabilities in …

36.1 A 32Gb/s 10.5Tb/s/mm 0.6pJ/b UCIe-Compliant Low-Latency Interface in 3nm Featuring Matched-Delay for Dynamic Clock Gating

Mu-Shan Lin, Chien-Chun Tsai, Shenggao Li, Wei‐Chih Chen et autres

Demand for chiplet integration using 2.5D or 3D packaging has surged due to the AI/MLdriven growth in computing performance. Universal Chiplet Interconnect Express (UCIe) has been developed to standardize chiplet interconnects, focusing on bandwidth density, energy efficiency, and latency. Dynamic clock gating …

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IC/BPS is not associated with bladder cancer: a nationwide propensity score matched cohort study in Taiwan

Ming‐Huei Lee, Huei‐Ching Wu, Wei‐Chih Chen, Yung-Fu Chen

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A Preliminary Exploration with GPT-4o Voice Mode

Yuxiang J. Lin, Chih-Kai Yang, Wei‐Chih Chen, Chen-An Li et autres

With the rise of multimodal large language models, GPT-4o stands out as a pioneering model, driving us to evaluate its capabilities. This report assesses GPT-4o across various tasks to analyze its audio processing and reasoning abilities. We find that GPT-4o exhibits strong …

Clinical Trial: Precise Administration of Sucralfate Powder in Prevention of Delayed Postpolypectomy Bleeding. A Randomized Controlled Trial

Hsueh‐Chien Chiang, Po‐Jun Chen, Er‐Hsiang Yang, Ming‐Tsung Hsieh et autres

INTRODUCTION: Delayed postpolypectomy bleeding occurs in approximately 1%-2% of all patients undergoing colonoscopic polypectomy, and this rate increases to 6% in patients with large (>2 cm) colon polyps. Sucralfate can protect the mucosa and promote its healing. This study was conducted to …

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