Koh Imbe

Guide Wire Selection (Straight vs. Angled) in Endoscopic Retrograde Cholangiopancreatography Using a Normal Contrast Catheter Performed by a Trainee: A Single-Center Prospective Randomized Controlled Cross-Over Study

Takumi Maki, Atsushi Irisawa, Akira Yamamiya, Keiichi Tominaga et autres

INTRODUCTION: Wire-guided cannulation (WGC) during endoscopic retrograde cholangiopancreatography (ERCP) is a selective biliary cannulation technique aimed at improving the successful selective biliary cannulation rate and reducing the rate of post-ERCP pancreatitis (PEP) incidence. This study aimed to evaluate the effectiveness of angled-tip …

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Metagenomic Identification of Microbial Signatures Predicting Pancreatic Cancer From a Multinational Study

Naoyoshi Nagata, Suguru Nishijima, Yasushi Kojima, Yuya Hisada et autres

BACKGROUND & AIMS: To identify gut and oral metagenomic signatures that accurately predict pancreatic ductal carcinoma (PDAC) and to validate these signatures in independent cohorts. METHODS: We conducted a multinational study and performed shotgun metagenomic analysis of fecal and salivary samples collected …

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Effect of antiplatelet agent number, types, and pre-endoscopic management on post-polypectomy bleeding: validation of endoscopy guidelines

Kazuhiro Watanabe, Naoyoshi Nagata, Naohiro Yanagisawa, Takuro Shimbo et autres

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Tu1240 – Assessment of Esophagel Bolus Transit and Peristaltic Integrity Using High-Resolution Impedance Manometry

Mariko Hamada, Junichi Akiyama, Tatsuhiro Iida, Atsuko Izumi et autres

Efficacy of Vonoprazan, a Novel Potassium-Competitive Acid Blocker, in Patients with Proton Pump Inhibitor-Refractory Acid Reflux

Junichi Akiyama, Hiroko Hosaka, Shiko Kuribayashi, Shiori Moriyasu et autres

BACKGROUND/AIM: We evaluated the efficacy of vonoprazan (VPZ), a novel potassium-competitive acid blocker, in patients with proton pump inhibitor (PPI)-refractory gastroesophageal reflux disease (GERD), exhibiting continued pathological esophageal acid exposure (EAE). METHODS: Despite ≥8 weeks of appropriate PPI therapy, patients with -persistent …

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Effects of bowel preparation on the human gut microbiome and metabolome

Naoyoshi Nagata, Mari Tohya, Shinji Fukuda, Wataru Suda et autres

Large bowel preparation may cause a substantial change in the gut microbiota and metabolites. Here, we included a bowel prep group and a no-procedure control group and evaluated the effects of bowel prep on the stability of the gut microbiome and metabolome …

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Validation of the American Gastroenterological Association guidelines on management of intraductal papillary mucinous neoplasms: more than 5 years of follow-up

Koh Imbe, Naoyoshi Nagata, Yuya Hisada, Yusuke Takasaki et autres

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Natural history of intraductal papillary mucinous neoplasm and non‐neoplastic cyst: long‐term imaging follow‐up study

Yuya Hisada, Naoyoshi Nagata, Koh Imbe, Yusuke Takasaki et autres

BACKGROUND: To identify differences in incidence and mortality of pancreatic cancer (PC) between intraductal papillary mucinous neoplasm (IPMN) and non-neoplastic cyst. METHODS: Patients with pancreatic cyst (n = 526; 263 with IPMN and 263 with non-neoplastic cyst matched for age, sex, and …

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Differences in Pancreatic Cancer Development and Pancreatic Cancer-Related Death between Intraductal Papillary Mucinous Neoplasm and Non-Neoplastic Cyst

Yuya Hisada, Naoyoshi Nagata, Koh Imbe, Yusuke Takasaki et autres

Efficacy of Vonoprazan, A Novel Potassium-Competitive Acid Blocker, in Patients with Gastroesophageal Reflux Disease Refractory to Proton Pump Inhibitors

Junichi Akiyama, Shiori Moriyasu, Yuya Hisada, Hidetaka Okubo et autres

Effect of low-dose aspirin use on pancreatic cancer development and morphological changes on imaging in IPMN: A long-term cohort study

Yusuke Takasaki, Naoyoshi Nagata, Koh Imbe, Yuya Hisada et autres

BackgroundAspirin use may reduce the incidence of pancreatic cancer (PC), but no data are available regarding its chemopreventive effects on intraductal papillary mucinous neoplasm (IPMN). We aimed to determine whether low-dose aspirin (LDA) reduces PC development and morphological changes on imaging in …

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A case of acquired hemophilia A presenting with repeated hemorrhagic esophagitis

Akira Shimomura, Chizu Yokoi, Toru Igari, Koh Imbe et autres

An 80-year-old man presented emergently with acute melena and hematemesis. Blood tests revealed anemia, with prolonged activated partial thromboplastin time and normal prothrombin time. Esophagogastroduodenoscopy showed severe esophagitis with hemorrhage ; and he required 10 units of blood transfusion. The intractable esophagitis …

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