Survival in post-endoscopy esophageal cancer: a Nordic population-based cohort study
Rattachement africain : se, us, no, dk, fi, gb. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Background: Post-endoscopy esophageal cancer (PEEC) (i.e. esophageal cancer diagnosed shortly after an endoscopy in which no cancer was found) constitutes about 5%-10% of all esophageal cancers. Long-term survival in PEEC has not been reported previously. Methods: This population-based cohort study included patients with a newly diagnosed esophageal cancer in Denmark, Finland, and Sweden between 2004 and 2022. Patients with PEEC (i.e. history of upper endoscopy 6-36 months before esophageal cancer diagnosis) were compared with patients with all other esophageal cancers (i.e. those without upper endoscopy 6-36 months before diagnosis). Outcomes were 5-year disease-specific mortality and 5-year all-cause mortality. Multivariable Cox regression was used to calculate hazard ratios (HRs) with 95%CIs, adjusted for country, age, sex, calendar year, comorbidity, and tumor histology. Results: Among 27 309 patients with esophageal cancer, 1588 (5.8%) were classified as having PEEC. The cumulative 5-year mortality among patients with PEEC was 74.6% (n = 1185), and 79.6% of these were disease-specific deaths (n = 943). PEEC was associated with decreased risks of both 5-year disease-specific mortality (HR 0.72, 95%CI 0.68-0.77) and 5-year all-cause mortality (HR 0.74, 95%CI 0.71-0.80). Stratified analysis found that the decreased 5-year disease-specific mortality in PEEC was limited to patients with adenocarcinoma (HR 0.57, 95%CI 0.52-0.62), whereas no such decrease was found among patients with squamous cell carcinoma (HR 1.04, 95%CI 0.95-1.15). Conclusions: 5-year survival in patients with PEEC seemed to be better than in those with other esophageal cancer, but the survival was still poor.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Survival in post-endoscopy esophageal cancer: a Nordic population-based cohort study
- Date Crossref
- 06/02/2026
- Éditeur
- Georg Thieme Verlag KG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Karolinska Institutet pays non établi dans la noticeUniversité ou école supérieure
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University of Colorado Anschutz pays non établi dans la noticeUniversité ou école supérieure
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Norwegian University of Science and Technology pays non établi dans la noticeUniversité ou école supérieure
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Levanger Hospital pays non établi dans la noticeÉtablissement de santé
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University of Copenhagen pays non établi dans la noticeUniversité ou école supérieure
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Oulu University Hospital pays non établi dans la noticeÉtablissement de santé
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University of Oulu pays non établi dans la noticeUniversité ou école supérieure
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Guy's and St Thomas' NHS Foundation Trust pays non établi dans la noticeÉtablissement de santé
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King’s College London pays non établi dans la noticeUniversité ou école supérieure
Karolinska Institutet, University of Colorado Anschutz et Norwegian University of Science and Technology, avec 6 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.