Edouard Guenzi

Collagenous colitis in patients treated for cancer: role of immune checkpoint inhibitors. Clinical, histological and immunological features in 15 cases

Mohamed Amine Bani, Peggy Dartigues, Ranya Soufan, Simona Cosconea et autres

BACKGROUND AND AIMS: Collagenous colitis is a rare complication of immunotherapy for cancer. We report here 15 cases in order to assess the role of immune checkpoint inhibitors (ICI) in the onset of this disease, describe the histopathological and immunological features of …

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Assessing personalized responses to anti-PD-1 treatment using patient-derived lung tumor-on-chip

Irina Veith, Martin Nurmik, Arianna Mencattini, Isabelle Damei et autres

There is a compelling need for approaches to predict the efficacy of immunotherapy drugs. Tumor-on-chip technology exploits microfluidics to generate 3D cell co-cultures embedded in hydrogels that recapitulate simplified tumor ecosystems. Here, we present the development and validation of lung tumor-on-chip platforms …

fr, it (code pays fourni par la source)

Autoantibodies are associated with disease progression in idiopathic pulmonary fibrosis

Katerina Koether, Valérie Besnard, Hilary Sandig, Alan M. Carruthers et autres

Several reports have highlighted a potential role of autoreactive B-cells and autoantibodies that correlates with increased disease severity in patients with idiopathic pulmonary fibrosis (IPF). Here we show that patients with IPF have an altered B-cell phenotype and that those subjects who …

gb, fr, us (code pays fourni par la source)

Pathologie infectieuse du tube digestif : diagnostics à ne pas manquer

Edouard Guenzi, Ruiqian Chen, Aurélie Sannier, Philippe Drabent et autres

fr (code pays fourni par la source)

« …ites » lymphocytaires, de l’œsophage au côlon

Edouard Guenzi, Nicolas Poté

fr (code pays fourni par la source)

Detection of Nine Oncogenes Amplification in Lung and Colorectal Cancer Formalin-Fixed Paraffin-Embedded Tissue Samples using Combined Next-Generation Sequencing-Based Script and Digital Droplet Polymerase Chain Reaction

Christophe Bontoux, Alice Guyard, Audrey Lupo, Karim Diallo et autres

Introduction Gene copy number variations have theranostic impact and require reliable methods for their identification. We aimed to evaluate the reliability of combined next-generation sequencing (NGS) and digital droplet PCR (ddPCR) method for gene amplification evaluation. Methods We conducted a retrospective multicentric …

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Perception de la spécialité et motivations dans le choix de l’anatomie pathologique aux épreuves classantes nationales : résultats d’une enquête française auprès des internes d’anatomie et cytologie pathologiques

Loïc Trapani, Edouard Guenzi, Anne Couvelard, Aurélie Sannier

fr (code pays fourni par la source)

A newKIF5B–ERBB4gene fusion in a lung adenocarcinoma patient

Edouard Guenzi, Johan Pluvy, Alice Guyard, Marina Nguenang et autres

ERBB4 fusion is a rare, novel oncogenic event involved in the development of lung adenocarcinoma that is not routinely looked for, although ERBB4 fusion is a potential target for existing pan-ErbB tyrosine kinase and must be implemented in the laboratoryhttps://bit.ly/3nYmGQ9

fr (code pays fourni par la source)

Lymphome à cellules du manteau : une entité très hétérogène sur le plan histopathologique et pronostique

Edouard Guenzi, Danielle Canioni, Julie Bruneau, Josette Brière et autres

fr (code pays fourni par la source)