Charles A. Hanson

Preimplantation genetic testing and child health: a national register-based study

Erica Ginström Ernstad, Charles A. Hanson, Kjell Wånggren, Ann Thurin‐Kjellberg et autres

STUDY QUESTION: Is preimplantation genetic testing (PGT) associated with adverse perinatal outcome and early childhood health? SUMMARY ANSWER: Children born after PGT had comparable perinatal outcomes to children born after IVF/ICSI and comparable findings regarding early childhood health. WHAT IS KNOWN ALREADY: …

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Comprehensive analysis of soluble RNAs in human embryo culture media and blastocoel fluid

Kirstine Kirkegaard, Yan Yan, Boe Sandahl Sørensen, Thorir Hardarson et autres

PURPOSE: miRNAs have been suggested as biomarkers of embryo viability; however, findings from preliminary studies are divergent. Furthermore, the presence of other types of small RNA molecules remains to be investigated. The purpose of this study was to perform a comprehensive analysis …

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Preimplantation genetic testing practices in the Nordic countries

Julius Gisli Hreinsson, Erik Iwarsson, Charles A. Hanson, Marie Louise Grøndahl et autres

INTRODUCTION: Preimplantation genetic testing (PGT) is growing in importance and volume internationally. International societies such as the European Society for Human Reproduction and Embryology compile international results and these data are published in scientific journals. We present the first compilation of practices, …

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Side differences in the degree of mosaicism of the buccal mucosa in Turner syndrome

Sofia Thunström, Kerstin Landin‐Wilhelmsen, Inger Bryman, Charles A. Hanson

BACKGROUND: The aim was to investigate if there were any differences in the degree of mosaicism between the left- and right-hand sides of the buccal mucosa in women with Turner syndrome. METHODS: Buccal smears were taken on the left- and right-hand sides …

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Incidence of Aortic Dissection in Turner Syndrome

Sofia Thunström, Emily Krantz, Erik Östgärd Thunström, Charles A. Hanson et autres

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Transplanting embryonic stem cells onto damaged human corneal endothelium

Charles A. Hanson, Ársæll Már Arnarsson, Thorir Hardarson, Ann Lindgård et autres

AIM: To investigate whether human embryonic stem cells (hESCs) could be made to attach, grow and differentiate on a human Descemet's membrane (DM). METHODS: Spontaneously differentiated hESCs were transferred onto a human corneal button with the endothelial layer removed using ocular sticks. …

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Conjunctival polyploid cells and donor-derived myofibroblasts in ocular GvHD

David Hallberg, Kjell Stenberg, Charles A. Hanson, Ulf Stenevi et autres

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152 BONE MARROW CONVENTIONAL KARYOTYPING AND FLUORESCENCE IN SITU HYBRIDIZATION (FISH): DEFINING AN EFFECTIVE UTILIZATION STRATEGY FOR THE EVALUATION OF MYELODYSPLASTIC SYNDROME (MDS)

Rong He, Anne E. Wiktor, PJ Kurtin, Daniel L. Van Dyke et autres

The Proportion of Diploid 46,XX Cells Increases with Time in Women with Turner Syndrome—A 10-Year Follow-Up Study

Anna-Maria Denes, Kerstin Landin‐Wilhelmsen, Yvonne Wettergren, Inger Bryman et autres

In the normal population, loss of one of the sex chromosomes leading to monosomy (45,X) is a part of the aging process. In Turner syndrome (TS), the classic karyotype 45,X is found in up to 50% at birth, and others have a …

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[Mitochondrial replacement--potential therapy method with ethical implications. Severe disease may be prevented, but knowledge gaps exist].

Karin Wilbe Ramsay, Charles A. Hanson, Kjell Asplund

Transplantation of human embryonic stem cells onto a partially wounded human cornea in vitro

Charles A. Hanson, Thorir Hardarson, Catharina Ellerström, Markus Nordberg et autres

PURPOSE: The aim of this study was to investigate whether cells originating from human embryonic stem cells (hESCs) could be successfully transplanted onto a partially wounded human cornea. A second aim was to study the ability of the transplanted cells to differentiate …

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Charles A. Hanson, Bob DeMeritt, Marianne DeMeritt