Franck Carbonnel

Virtual reality combined with patient-controlled anaesthesia for pain management during pancreatic extracorporeal shockwave lithotripsy

Abel Galland, Antoine Meyer, Antonia Blanié, Aurélien Amiot et autres

Objective Extracorporeal shock wave lithotripsy (ESWL) for pancreatic duct stones is effective but painful. We aimed to evaluate whether combining virtual reality (VR) with remifentanil patient-controlled analgesia (PCA) reduces opioid consumption and improves recovery after pancreatic ESWL. Methods We conducted a single-centre …

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Five-year effectiveness of either ustekinumab or vedolizumab in 239 patients with Crohn's disease refractory to anti-tumour necrosis factor

Aurélien Amiot, Julien Kirchgesner, Hadrien Alric, Xavier Tréton et autres

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Gastrointestinal complications of immune checkpoint Inhibitor therapy

Franck Carbonnel, Antoine Martin, Lysiane Marthey, Christophe Bellanger et autres

Immune checkpoint inhibitors (ICI) have improved the prognosis of several cancers. ICI enhance T-cell activation, and therefore stimulate anti-cancer immunity, but also cause immune related adverse effects (irAE), including those affecting the gastrointestinal (GI) tract. GI-irAE are observed in 7 to 30 …

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Relapse rate following withdrawal of vedolizumab and ustekinumab in patients with inflammatory bowel disease - a multicenter retrospective controlled study. The VEDUST-EXIT Study

Ahmad Albshesh, Piotr Kucha, Daniela Pugliese, Aurélien Amiot et autres

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Blood proteomic signatures associated with disease activity in inflammatory bowel diseases

Maëva Veyssière, Nassim Hammoudi, Lionel Le Bourhis, Déborah Hassid et autres

BACKGROUND AND AIMS: Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), remain heterogeneous disorders with variable response to biologics. Post-operative recurrence in CD is common despite surgery and prophylactic biotherapies. Understanding the inflammatory mediators associated with recurrence and …

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Collagenous colitis in patients treated for cancer: role of immune checkpoint inhibitors. Clinical, histological and immunological features in 15 cases

Mohamed Amine Bani, Peggy Dartigues, Ranya Soufan, Simona Cosconea et autres

BACKGROUND AND AIMS: Collagenous colitis is a rare complication of immunotherapy for cancer. We report here 15 cases in order to assess the role of immune checkpoint inhibitors (ICI) in the onset of this disease, describe the histopathological and immunological features of …

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Impact of diet on inflammatory bowel disease risk: systematic review, meta-analyses and implications for prevention

Antoine Meyer, Manasi Agrawal, Einat Savin-Shalom, Emily C L Wong et autres

Background: Data on dietary risk factors for inflammatory bowel disease (IBD), while extensive, are inconsistent. Our aim was to systematically review and meta-analyze available data unraveling the relationship between diet and IBD subtypes, Crohn's disease (CD) and ulcerative colitis (UC). Methods: We …

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Fruits, Vegetables, Legumes, and Potatoes and Risk of Crohn's Disease and Ulcerative Colitis

Antoine Meyer, Franck Carbonnel, Christina C. Dahm, Jytte Halkjær et autres

INTRODUCTION: Low intake of fiber, fruits, and vegetables is associated with the risk of developing Crohn's disease (CD) and ulcerative colitis (UC). We therefore aimed to assess the risk of developing CD and UC according to individual fruits, vegetables, legumes, and potatoes …

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A randomized controlled trial of antibiotics targeting adherent and invasive Escherichia coli versus placebo in Crohn’s disease: the TEOREM trial

Franck Carbonnel, Nicolas Barnich, Patricia Lepage, Xavier Hébuterne et autres

BACKGROUND: A subset of patients with ileal Crohn's disease (CD) are colonized with adherent-invasive Escherichia coli (AIEC). OBJECTIVE: This prospective trial tested the efficacy of antibiotics for endoscopic response in CD patients colonized with AIEC. DESIGN: Patients with endoscopically active, ileal CD, …

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Severe enterocolitis associated with phosphatidylinositol 3‐kinase delta inhibitors: A multicentre cohort study

Véred Abitbol, Mathieu Uzzan, Nassim Hammoudi, Jean‐Marie Michot et autres

fr (code pays fourni par la source)

Adherent-invasive Escherichia coli in Crohn’s disease: the 25th anniversary

Nicolas Barnich, Janelle C. Arthur, Anthony Buisson, Barry J. Campbell et autres

In 1998, Arlette Darfeuille-Michaud, Christel Neut and Jean-Frederic Colombel discovered a novel pathovar of Escherichia coli , adherent and invasive Escherichia coli (AIEC), in the ileum of patients with Crohn’s disease (CD), that was genetically distinct from diarrheagenic E. coli , could …

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CONCORDANCE BETWEEN AUTOMATED 3D BILIARY TRACT RECONSTRUCTION AND ERCP IN PATIENTS WITH HILAR CHOLANGIOCARCINOMA

Antoine Martin, Omar Bekdache, Antoine Meyer, Carole Bassil et autres