Patrick Lévy

Rapport 26-04. Le sommeil de l’enfant et de l’adolescent

Patrick Lévy, Yves Dauvilliers

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Jouir sans entrave

Patrick Lévy

Observational studies versus RCTs in sleep apnoea treatment: towards a more pragmatic and less ideological approach

Raphaël Heinzer, Patrick Lévy

Extract The association between obstructive sleep apnoea (OSA) and cardiovascular disease has long been recognised, but the role of positive airway pressure (PAP) therapy in modifying cardiovascular risk remains controversial [1–7]. Over the past decade, large randomised controlled trials (RCTs) such as …

ch, fr (code pays fourni par la source)

Assessing new treatments for central sleep Apnoea in heart failure: sample size considerations for reliable detection of safety signals

Holger Woehrle, Karl Wegscheider, Anita K. Simonds, Michael Arzt et autres

PURPOSE: Central sleep apnoea (CSA) and Cheyne-Stokes respiration (CSR) are prevalent in patients with heart failure with reduced ejection fraction (HFrEF) and are associated with increased mortality. Previous trials evaluating adaptive servo-ventilation (ASV) for CSA/CSR in HFrEF have yielded conflicting safety outcomes. …

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Adaptive servo-ventilation for central sleep apnoea in heart failure: where are we?

Patrick Lévy

Extract Heart failure (HF) is a very common condition. It is a clinical syndrome with current or prior symptoms and/or signs caused by a structural and/or functional cardiac abnormality, corroborated by either elevated natriuretic peptide and/or objective evidence of cardiogenic pulmonary or …

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EPH275 Treatment Patterns and Patients’ Pathways in Actinic Keratosis Population: A Retrospective Longitudinal Cohort Study in the French National Health Insurance Claim Database (SNDS)—EPIKA Study

Patrick Lévy, JM Amici, G. Caillet, Amandine Gouverneur et autres

fr, gb, us, es (code pays fourni par la source)

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

Anne Briançon‐Marjollet, Marie Netchitaïlo, F Fabre, Elise Belaïdi et autres

Sympathetic overactivity caused by chronic intermittent hypoxia is a hallmark of obstructive sleep apnea. A high sympathetic tone elicits increases in plasma free fatty acid and insulin. Our objective was to assess the impact of 14 nights of chronic intermittent hypoxia exposure …

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ICSI avec incubation en milieu hypo-osmotique des spermatozoïdes chez les hommes porteurs de réarrangements chromosomiques équilibrés

L. Debain, A. Paulet, Eli Rogers, Nathalie Lédée et autres

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Automatic sleep stage identification: difficulties and possible solutions

Nadezda Sukhorukova, Andrew Stranieri, Bahadorreza Ofoghi, Peter Vamplew et autres

The diagnosis of many sleep disorders is a labour intensive task that involves the specialised interpretation of numerous signals including brain wave, breath and heart rate captured in overnight polysomnogram sessions. The automation of diagnoses is challenging for data mining algorithms because …

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PCR93 Actinic Keratosis: Patient Perceptions and Expectations for Treatment (REAKT Study)

J.-M. Amici, Patrick Lévy, G. Caillet, C. Touboul et autres

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Long-Term Efficacy and Safety of Pitolisant for Residual Sleepiness Due to OSA

Jean‐Louis Pépin, Valérie Attali, Christian Caussé, Johan Verbraecken et autres

BACKGROUND: In people with OSA, excessive daytime sleepiness is a prominent symptom and can persist despite adherence to CPAP, the first-line therapy for OSA. Pitolisant was effective in reducing daytime sleepiness in two 12-week randomized controlled trials (RCTs), one in patients adherent …

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Intermittent hypoxia exposure increases adipose insulin resistance and lipolysis in healthy humans: a randomized cross over trial.

Anne Briançon‐Marjollet, Marie Netchitaïlo, F Fabre, Elise Belaïdi et autres

Sympathetic overactivity caused by chronic intermittent hypoxia (CIH) is a landmark of obstructive sleep apnoea (OSA). A high sympathetic tone elicits rises in plasma free fatty acid (FFA) and insulin. Our objective was to assess the impact of 14 nights of CIH …

fr (code pays fourni par la source)