Marie Richards

House dust metagenome and pulmonary function in a US farming population

Mi Kyeong Lee, Abhishek Kaul, James Mace Ward, Qiyun Zhu et autres

Abstract Background Chronic exposure to microorganisms inside homes can impact respiratory health. Few studies have used advanced sequencing methods to examine adult respiratory outcomes, especially continuous measures. We aimed to identify metagenomic profiles in house dust related to the quantitative traits of …

us (code pays fourni par la source)

Comprehensive evaluation of smoking exposures and their interactions on DNA methylation

Thanh T. Hoang, Yunsung Lee, Daniel L. McCartney, Elin T.G. Kersten et autres

BACKGROUND: Smoking impacts DNA methylation, but data are lacking on smoking-related differential methylation by sex or dietary intake, recent smoking cessation (<1 year), persistence of differential methylation from in utero smoking exposure, and effects of environmental tobacco smoke (ETS). METHODS: We meta-analysed …

us, no, gb, nl (code pays fourni par la source)

Early-life farm exposures and eczema among adults in the Agricultural Lung Health Study

Annah B. Wyss, Thanh T. Hoang, Hilde Kristin Vindenes, Julie D. White et autres

Background: Several studies conducted in Europe have suggested a protective association between early-life farming exposures and childhood eczema or atopic dermatitis; few studies have examined associations in adults. Objectives: To investigate associations between early-life exposures and eczema among 3217 adult farmers and …

us, no (code pays fourni par la source)

Residential Wood Burning and Pulmonary Function in the Agricultural Lung Health Study

Julie D. White, Annah B. Wyss, Thanh T. Hoang, Mi Kyeong Lee et autres

Background: In low- and middle-income countries, burning biomass indoors for cooking or heating has been associated with poorer lung function. In high-income countries, wood, a form of biomass, is commonly used for heating in rural areas with increasing prevalence. However, in these …

us (code pays fourni par la source)

Epigenome-Wide DNA Methylation and Pesticide Use in the Agricultural Lung Health Study

Thanh T. Hoang, Cancan Qi, Kimberly C. Paul, Mi Kyeong Lee et autres

BACKGROUND: Pesticide exposure is associated with many long-term health outcomes; the potential underlying mechanisms are not well established for most associations. Epigenetic modifications, such as DNA methylation, may contribute. Individual pesticides may be associated with specific DNA methylation patterns but no epigenome-wide …

us, nl, de (code pays fourni par la source)

Interaction between Genetic Risk Scores for reduced pulmonary function and smoking, asthma and endotoxin

Sinjini Sikdar, Annah B. Wyss, Mi Kyeong Lee, Thanh T. Hoang et autres

Rationale Genome-wide association studies (GWASs) have identified numerous loci associated with lower pulmonary function. Pulmonary function is strongly related to smoking and has also been associated with asthma and dust endotoxin. At the individual SNP level, genome-wide analyses of pulmonary function have …

us (code pays fourni par la source)

Pesticide Exposure and Depression among Male Private Pesticide Applicators in the Agricultural Health Study

Jane A. Hoppin, Freya Kamel, Marie Richards, David M. Umbach et autres

Background: Pesticide exposure may be positively associated with depression. Few previous studies have considered the episodic nature of depression or examined individual pesticides.

Pesticide exposure and self-reported incident depression among wives in the Agricultural Health Study

Marie Richards, Michael C.R. Alavanja, Freya Kamel, Jane A. Hoppin et autres

Depression in women is a public health problem. Studies have reported positive associations between pesticides and depression, but few studies were prospective or presented results for women separately.

Protective glove use and hygiene habits modify the associations of specific pesticides with Parkinson's disease

Monica Korell, George Webster Ross, Grace S. Bhudhikanok, Freya Kamel et autres

Pesticides have been associated with Parkinson’s disease (PD), and protective gloves and workplace hygiene can reduce pesticide exposure. We assessed whether use of gloves and workplace hygiene modified associations between pesticides and PD. The Farming and Movement Evaluation (FAME) Study is a …

Epigenome-wide Association Study of DNA Methylation and Specific Pesticide Use Among U.S. Farmers

Thanh T. Hoang, M. Lee, Marie Richards, Smeeta Shrestha et autres

Background: Pesticide exposure is associated with certain cancers and neurologic diseases, but the underlying mechanisms are not fully understood. DNA methylation, an epigenetic modification, may play a role. DNA methylation patterns likely differ by specific pesticide, but no epigenome-wide association studies have …

us (code pays fourni par la source)

House dust microbiota in relation to adult asthma and atopy in a US farming population

Mi Kyeong Lee, Annah B. Wyss, Megan Ulmer Carnes, Marie Richards et autres

BACKGROUND: Bacterial exposure from house dust has been associated with asthma and atopy in children but whether these relationships are present in adults remains unclear. OBJECTIVE: We sought to examine associations of house dust microbiota with adult asthma, atopy, and hay fever. …

us (code pays fourni par la source)

Considerations on equity in management of end-stage kidney disease in low- and middle-income countries

Wim Van Biesen, Vivekanand Jha, Ali K. Abu‐Alfa, Sharon Phillips Andreoli et autres

be, in, gb, lb, us, Cameroun, ae, cn, it, fr, Afrique du Sud, ar, Nigéria, ca, ch, au, at, cz, mx (code pays fourni par la source)