Simin Zhao

Photovoltaic Cell Surface Defect Detection Based on Wavelet-Aware Perception and Selective Reconstruction

Li Yang, Simin Zhao, Hailong Duan, Xinrui Kan et autres

Defect detection in electroluminescence (EL) images of solar cells remains challenging because defects are often small, exhibit subtle grayscale variations, and are obscured by complex cell-texture backgrounds. These conditions can attenuate defect features as they propagate through deep layers and make them …

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Analytical validation of a chemiluminescent immunoassay for plasma Aβ1–40 and exploratory clinical associations in neurological disorders

Shuang Han, Tianhui Yu, Wenjun Yan, Simin Zhao et autres

Background Alzheimer’s disease (AD) remains a major unmet medical need. Increasing evidence indicates that disease-modifying therapies are most likely to be effective when initiated early, underscoring the need for accessible biomarkers that enable detection at the earliest stages. Aβ1–40 is a clinically …

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Pleasantness shapes congruency effects in odor-induced taste enhancement

Ao Wang, Xinyi Wu, Lin Gao, Qingya Yang et autres

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Quality-driven unsupervised data curation and robust learning method for bird image data

Zhiyao Zhao, Xinxin Duan, Yuqin Zhou, Simin Zhao et autres

Data acquisition for river-lake avian species suffers from interference by long-distance imaging, water surface reflections and occlusions, producing low-quality images with motion blur, low contrast and annotation noise. Such defects severely degrade the accuracy of classification models. To address this problem, this …

Tumor-derived progranulin promotes macrophage cholesterol efflux and associated immunosuppressive features in oral squamous cell carcinoma

Yijun Luan, Yi Xu, Simin Zhao, Hao Li et autres

Cholesterol efflux is increasingly recognized as an important regulator of macrophage polarization and immunosuppressive features; however, the tumor-derived signals that govern this process in oral squamous cell carcinoma (OSCC) remain poorly defined. We performed integrated single-cell RNA sequencing (scRNA-seq) on primary OSCC …

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The discovery and the clinical significance of autoantibodies against fibroblast activation proteins in interstitial lung disease

Junqi Li, Huimin Huang, Qi Fang, Yuan Lyu et autres

Interstitial lung disease (ILD) was a chronic, progressive, and irreversible fibrotic condition associated with high mortality. Current standard diagnosis relied primarily on invasive modalities such as high-resolution computed tomography (HRCT) and biopsy, highlighting the urgent need for a noninvasive and accurate screening …

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Development of Free Testosterone Chemiluminescence Detection Kit and Its Clinical Application

Shuang Han, Min Liu, Simin Zhao, W. B. Yan et autres

Abstract Background: Free testosterone makes up only 1–2% of the total testosterone in the blood, but it is the active form of testosterone and enters cells directly to work. The level of total testosterone is substantially affected by sex hormone-binding globulin, whereas …

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Ultraviolet A plays a protective role in ultraviolet B-induced squamous cell carcinoma through c-Fos/XRCC4 axis

Yifei Xie, Yao Ke, Yongfeng Wu, Chaopu Ding et autres

For decades, there has been a strong epidemiological association between solar ultraviolet (UV) radiation and skin cancer. UVB and UVA are the major UV bands that can penetrate the atmosphere, playing vital roles in skin carcinogenesis. Our research group previously discovered that …

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Enhancing taste without salt or sugar: Cross-modal flavor modulation via olfactory cues

Ao Wang, Xinyi Wu, Lin Gao, Yang Qu et autres

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Tumor-derived progranulin reprograms immunosuppressive macrophages via cholesterol efflux in oral squamous cell carcinoma

Chengzhe Yang, Yan Xu, Simin Zhao, Hao Li et autres

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Tasting emotions: An in-depth fmri study exploring gustatory and visual cross-modal associations across various spatio-temporal regions of the human brain

Jie Chen, Lina Huang, Luming Hu, Xueying Li et autres

• Sour taste facilitates recognition of disgusted faces, while sweet taste enhances detection of pleasant expressions. • Task-based fMRI reveals interaction effects in the primary visual cortex (V1) and activations in the medial cingulate and frontal regions. • Resting-state fMRI demonstrates lasting …

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The pro-cancer and immunosuppressive activity of macrophage-transformed cancer-associated fibroblasts in oral squamous cell carcinoma

Haoyang Tian, Simin Zhao, Fujiao Nie, Suli Wang et autres

INTRODUCTION: Cancer-associated fibroblasts (CAFs), as a crucial component of the tumor microenvironment (TME), exhibit heterogeneity, and macrophage-myofibroblast transition (MMT) has been demonstrated to be one of the origins of CAFs. However, the existence and functional features of MMT cells (MMTs) relative to …

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