Dieuwke Luijten

YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism in Patients With Cancer

Bram Akerboom, Emily S.L. Martens, Milou A.M. Stals, Rolf E. Brouwer et autres

Importance: Although the YEARS algorithm is a safe and efficient way to rule out acute pulmonary embolism (PE), robust evidence on its accuracy in patients with cancer is lacking, and current guidelines suggest proceeding directly to computed tomographic pulmonary angiography (CTPA). Objective: …

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Geriatric characteristics and outcomes of older patients diagnosed with acute pulmonary embolism in the emergency department

Denise Abbel, Dieuwke Luijten, Suzanne C. Cannegieter, Jeroen Eikenboom et autres

Introduction Knowledge on characteristics and outcomes of older patients with pulmonary embolism (PE) fuels decision making on PE management, but data are scarce. We aimed to describe geriatric characteristics and outcomes of older patients diagnosed with PE in the Emergency Department. Methods …

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Optimising communication to patients with venous thromboembolism: development of a provider toolkit

Frederikus Albertus Klok, Scott C. Woller, Aviva Schwartz, Samarth Mishra et autres

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Cardiopulmonary Exercise Testing in People With Dyspnea With a Recent Acute Pulmonary Embolism

Dieuwke Luijten, Josien van Es, Jannie J. Abbink, Stefano Barco et autres

Background: Cardiopulmonary exercise testing (CPET) may provide a helpful tool to assess underlying causes of dyspnea in patients with acute pulmonary embolism (PE). However, the response to exercise in the first weeks after diagnosis of an acute PE is currently unknown. Research …

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An assessment of evidence to inform best practice for the communication of acute venous thromboembolism diagnosis: a scoping review

Samarth Mishra, Frederikus Albertus Klok, Grégoire Le Gal, Kerstin de Wit et autres

Background: Physician communication with patients is a key aspect of excellent care. Scant evidence exists to inform best practice for physician communication in patients diagnosed with pulmonary embolism and deep vein thrombosis, collectively referred to as venous thromboembolism (VTE). Objectives: The aim …

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The value of vector ECG in predicting residual pulmonary hypertension in CTEPH patients after pulmonary endarterectomy

Dieuwke Luijten, T.B. Rodenburg, Harm Jan Bogaard, Azar Kianzad et autres

INTRODUCTION: Right heart catheterization (RHC) is the diagnostic standard for establishing residual pulmonary hypertension (PH) after pulmonary endarterectomy (PEA) in patients with chronic thromboembolic pulmonary hypertension (CTEPH). A potential non-invasive alternative diagnostic test could be electrocardiography (ECG)-derived ventricular gradient optimized for right …

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An assessment of evidence to inform best practice for the communication of acute venous thromboembolism diagnosis: a scoping review

Samarth Mishra, Frederikus Albertus Klok, Grégoire Le Gal, Kerstin de Wit et autres

Abstract Background Physician communication with patients is a key aspect of excellent care. Scant evidence exists to inform best practice for physician communication in patients diagnosed with pulmonary embolism and deep vein thrombosis, collectively referred to as venous thromboembolism (VTE). The aim …

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Risk assessment and management strategies in older patients with acute pulmonary embolism

Dieuwke Luijten, Denise Abbel, Suzanne C. Cannegieter, Jeroen C.J. Eikenboom et autres

BACKGROUND: Managing older patients with acute pulmonary embolism (PE) is challenging due to their underrepresentation in clinical trials, comorbidities, and increased complication risk. OBJECTIVES: To evaluate risk assessment and management outcomes in older patients with PE focusing on home and reperfusion treatment. …

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Cost-effectiveness of follow-up algorithms for chronic thromboembolic pulmonary hypertension in pulmonary embolism survivors

Dieuwke Luijten, Wilbert B. van den Hout, Gudula J.A.M. Boon, Stefano Barco et autres

Introduction: Achieving an early diagnosis of chronic thromboembolic pulmonary hypertension (CTEPH) in pulmonary embolism (PE) survivors results in better quality of life and survival. Importantly, dedicated follow-up strategies to achieve an earlier CTEPH diagnosis involve costs that were not explicitly incorporated in …

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Incidence and clinical course of chronic thromboembolic pulmonary hypertension with or without a history of venous thromboembolism in Denmark

Frederikus Albertus Klok, Emese Vágó, Erzsébet Horváth–Puhó, Stefano Barco et autres

BACKGROUND: A considerable number of patients with chronic thromboembolic pulmonary hypertension (CTEPH) lack a history of venous thromboembolism (VTE). OBJECTIVES: We aimed to examine the annual incidence and prevalence of CTEPH in Denmark and to compare the rates of VTE, bleeding, and …

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Safety of treating acute pulmonary embolism at home: an individual patient data meta-analysis

Dieuwke Luijten, Delphine Douillet, Kim Luijken, Cécile Tromeur et autres

BACKGROUND AND AIMS: Home treatment is considered safe in acute pulmonary embolism (PE) patients selected by a validated triage tool (e.g. simplified PE severity index score or Hestia rule), but there is uncertainty regarding the applicability in underrepresented subgroups. The aim was …

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Optimisation of detecting chronic thromboembolic pulmonary hypertension in acute pulmonary embolism survivors: the InShape IV study

Dieuwke Luijten, Luca Valerio, Gudula J.A.M. Boon, Stefano Barco et autres

INTRODUCTION: Chronic thromboembolic pulmonary hypertension (CTEPH) is often diagnosed late in acute pulmonary embolism survivors: more efficient testing to expedite diagnosis may considerably improve patient outcomes. The InShape II algorithm safely rules out CTEPH (failure rate 0.29%) while requiring echocardiography in only …

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