Rajesh Sinha

Message from the Outgoing President: Reflecting on a Journey of Learning, Growth, and Progress

Rajesh Sinha

Dear Friends and Members of the DOS Family, As I prepare to step down and pass the torch of leadership, my heart is filled with profound gratitude, humility, and immense pride. Serving as the President of the Delhi Ophthalmological Society (DOS) has …

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Association of Serum Vitamin D3 Levels with Severity of Acne Vulgaris: A Prospective Cross-Sectional Study

Varsha Rani, Rajesh Sinha, Kranti Chandan Jaykar, UK Pallavi

Background: Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous unit with multifactorial etiology. Emerging evidence suggests that vitamin D3, owing to its immunomodulatory and anti-inflammatory properties, may influence acne severity. Aim: To evaluate the association between serum vitamin D3 levels …

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Topical Sirolimus 0.2% ointment in the Management of Facial Angiofibroma

Rajesh Sinha, Sangita Singh, Varsha Rani

Background: Benign vascular tumors called facial angiofibromas are frequently linked to tuberous sclerosis complex (TSC). Both psychological discomfort and cosmetic damage could result from them. Topical sirolimus has emerged as a promising non-invasive therapy. Objective: To evaluate the efficacy and safety of …

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Successful treatment of pseudoepitheliomatous keratotic and micaceous balanitis with topical 5-fluorouracil

U. K. Pallavi, Shivani, Sangita Singh, Rajesh Sinha et autres

Pseudoepitheliomatous keratotic and micaceous balanitis (PKMB) is a rare penile condition usually seen in elderly uncircumcised men. We report a case of PKMB in a 41-year-old circumcised male presenting with a hyperkeratotic plaque on the glans penis. Histopathology showed features of PKMB …

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Correlation of change in V4c implantable Collamer lens vaulting and pupil diameter in different light conditions

Rajesh Sinha, Reena Singh, Manasi Tripathi, M. Sravanthi et autres

PURPOSE: To study the change in the vault of phakic Intraocular Lens (IOL) (pIOL) with RT view anterior segment optical coherence tomography (ASOCT) in different light conditions and define its relationship with the change in pupillary diameter. DESIGN: Prospective Observational Study. METHODS: …

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Asymmetrical Brachial Plexus Involvement with Greater Auricular Nerve Involvement in Borderline Tuberculoid Leprosy: An Electrophysiological and Radiological Correlation

Nimisha Kabra, Rajesh Sinha, Aditya A. Jaiswal, Pushpa Ranjan

, is known for mainly affecting the peripheral nerves. But in recent years, there is growing recognition that it can also involve the central nervous system, including the spinal cord and the brachial plexus. This broader understanding of nerve involvement highlights the …

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Cutaneous adverse drug reactions and their impact on the quality of life of patients: a study at a tertiary care centre

Shivani Shivani, Rajesh Sinha, Amrendra Kumar Arya, Kranti Chandan Jaykar et autres

Background and objective: Cutaneous adverse drug reactions (CADRs) encompass a wide spectrum of drug-induced skin and mucosal manifestations, ranging from mild rashes to severe cutaneous adverse reactions (SCARs), such as toxic epidermal necrolysis. Early recognition and prompt withdrawal of the causative drug …

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Estimation of Tear Film Concentration of Oral Ciprofloxacin in Patients With Bacterial Keratitis

Virendra Kumar Bagraniya, Manasi Tripathi, Nishat Hussain Ahmed, Rajesh Sinha et autres

AIMS: To estimate the tear film concentration of oral ciprofloxacin in patients with bacterial keratitis and evaluate its correlation with various clinical factors. METHOD: This prospective intraindividual study enrolled 52 patients (104 eyes), each with unilateral, microbiologically confirmed bacterial keratitis (n=52 eyes); …

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Inhibition of BRD4 prevents peribronchial fibrosis in mice with cutaneous lewisite exposure

Huaxiu Zeng, Pooja Singh, Rajesh Sinha, C.T. Stephens et autres

Introduction: Arsenicals like lewisite are highly toxic vesicant chemical warfare agents that cause severe skin damage and systemic inflammation. Exposure activates cytokine release, leading to pulmonary injury, including edema, hemorrhage, and in severe cases, Bronchiolitis Obliterans Syndrome (BOS), marked by airway fibrosis …

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Tuberculosis verrucosa cutis: An easy spotter yet frequently missed!

Nimisha Kabra, Rajesh Sinha

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Comparative Evaluation of 26-Gauge Needle Versus Kimura Spatula for Corneal Scraping in Infective Keratitis: A Randomized Controlled Trial

Prafulla K. Maharana, Aafreen Bari, Sohini Mandal, Nishat Hussain et autres

PURPOSE: Microbial keratitis accounts for significant proportion of corneal blindness. To know the underlying etiological micro-organism, performing corneal scraping is important for initiating the correct antibiotic therapy. A study was conducted to compare the efficacy and safety of 26-gauge needle and Kimura …

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Cadmium exposure triggers vimentin phosphorylation via SIRT6-regulated AKT/PI3K signaling pathway in COPD

Rajesh Sinha, Pooja Singh, Huaxiu Zeng, Abhishek Kumar et autres

Chronic Obstructive pulmonary disease (COPD) is a global health concern affecting over 300 million individuals worldwide, with airway fibrosis and subsequent small airway narrowing identified as the primary mechanism driving disease progression. This pathological process is characterized by accelerating lung aging, manifesting …

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