Accès ouvert
2026
article
OpenAlex
Lucia Bellanova, Antonio Scarano, Carlotta Viappiani, Matteo Mariangeli et autres
Abstract Although genetically encoded fluorescent sensors are fundamental tools to gain an understanding of intracellular nitric oxide (NO) dynamics, their development is still limited. We recently introduced the blue-emitting fluorescent protein (FP) mTagBFP2 as a NO sensor, where the chromophoric group formed …
it, de
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Accès ouvert
2026
article
OpenAlex
Pietro Delcanale, Andrea Mussini, Òscar Gulías, Montserrat Agut et autres
Staphylococcus aureus is a widespread human pathogenic bacterium that poses an increasingly serious threat to public health worldwide, due to the emergence and spread of antibiotic-resistant strains. A key virulence mechanism is the acquisition of iron from the heme group of human …
it, es
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Accès ouvert
2026
article
OpenAlex
Giuseppina Basini, M Berni, Laura Mazzera, Martina Tambassi et autres
Ivermectin (IVM), a widely used antiparasitic, raises emerging concerns regarding reproductive toxicity. This study investigated the effects of clinically relevant IVM concentrations (20, 40, 60 ng/mL) on endothelial cells from porcine corpus luteum, a translational model for vascular function. Proliferation and metabolic …
it
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Accès ouvert
2026
article
OpenAlex
Giuseppina Basini, Martina Tambassi, Simona Bussolati, Francesca Grasselli et autres
Nanoplastic fragments (NP) are a growing concern and using dog aortic endothelial cells (CnAEOC) and fluorescence microscopy, we observed an interaction between NP and cells, demonstrating a localization at the cytoplasmic level. Furthermore, the data collected show a disruption of both cell …
it
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Accès ouvert
2025
article
OpenAlex
Luca Bolzoni, Erika Scaltriti, Chiara Bracchi, Sara Angelone et autres
Between 2021 and 2024, we detected carbapenemase gene blaOXA-181 in 16 of 11,398 Salmonella enterica (SE) isolates: 10 SE 1,4,[5],12:i:-, three Bovismorbificans, two London and one Rissen from pigs, humans, pork meat and wild roe deer. The gene was first detected in …
it
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Accès ouvert
2024
article
OpenAlex
Martina Tambassi, M Berni, Chiara Bracchi, Ilaria Menozzi et autres
ABSTRACT Human salmonellosis is a high-priority foodborne disease worldwide. The main reservoir of Salmonella is livestock, mainly swine and poultry that are infected both by generalist serovars and serovars adapted to them. The most widespread livestock-adapted serovars are attenuated in both their …
it
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Accès ouvert
2024
article
OpenAlex
Giuseppina Basini, Simone Bertini, Simona Bussolati, Francesca Zappavigna et autres
Nanoplastics (NPs) affect fertility. We evaluated the effects of NPs treatment on luteal and endothelial cells. We examined crucial markers of growth and redox status. NPs treatment did not induce changes in ATP levels in luteal cells, while it increased (p< 0.05) …
it
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Accès ouvert
2024
article
OpenAlex
Andrea Mussini, Pietro Delcanale, M Berni, Stefano Pongolini et autres
Modular supramolecular complexes, where different proteins are assembled to gather targeting capability and photofunctional properties within the same structures, are of special interest for bacterial photodynamic inactivation, given their inherent biocompatibility and flexibility. We have recently proposed one such structure, exploiting the …
it, es, us
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Accès ouvert
2023
article
OpenAlex
Giuseppina Basini, Stefano Grolli, Simone Bertini, Simona Bussolati et autres
Plastic is an important environmental issue and a more critical aspect concerns plastic fragments, mainly in term of nanoplastics (NPs). We demonstrated that NPs interfere with reproductive and adipose stromal cells. Since several research underlined an increased cardiovascular risk due to NPs, …
it
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Accès ouvert
2023
article
OpenAlex
M Berni, Luca Bolzoni, Ilaria Menozzi, Alessandra Dodi et autres
ABSTRACT We report the identification, within the global population of Salmonella Derby, of a lineage highly diffused and expanding in swine while being significantly under-represented in humans which carries stop mutations in the Salmonella Pathogenicity Island 1 (SPI-1) genes sipA and hilC …
it
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Accès ouvert
2023
article
OpenAlex
Martina Tambassi, Elena Passarini, Ilaria Menozzi, M Berni et autres
A clinical strain of Klebsiella pneumoniae typed as sequence type 307 carrying three different alleles of the flu gene encoding the Escherichia coli virulence factor antigen 43 associated with biofilm formation was detected and characterized. The flu alleles are located in the …
it
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2022
article
OpenAlex
M Berni, Stefano Pongolini, Martina Tambassi
Salmonella is an enteric pathogen able to invade the intestinal epithelium and replicate in enterocytes, both inside Salmonella-specific vacuoles and free in the cytosol (cytosolic hyper-replication). These different phenotypes of intracellular replication drive to different pathways of pathogenesis, i.e., cytosolic hyper-replication induces …
it
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