Kyoichi Adachi

Five‐Year Unified Risk Prediction Model for Gastric and Esophageal Cancer Based on Nationwide Health Check‐Up Data in Japan: J‐GESS Score

Kenta Watanabe, Sho Fukuda, Dai Kubota, Nobutake Yamamichi et autres

BACKGROUND AND AIM: In Japan, gastric cancer (GC) and esophageal squamous cell carcinoma (ESCC) account for nearly all fatal upper gastrointestinal malignancies. A unified model that simultaneously predicts the incidence of these two cancers could help optimize endoscopic screening and postindex surveillance …

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Gastric Epithelial Neoplasms with Fundic Gland Mucosa Lineage - Size and Morphology Correlate Well with Tumor Depth

Kyoichi Adachi, Utae Sakamoto, Eiko Okimoto, Yuko Matsubara et autres

Objective Gastric adenocarcinoma of the fundic gland type (GA-FG) without submucosal invasion is classified as an oxyntic gland adenoma (OGA). This study aimed to investigate differences in characteristics between OGAs and GA-FGs with submucosal invasion. Methods A retrospective analysis of 15 OGAs …

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The Prevalence and Associated Factors of Reflux Esophagitis During the COVID-19 Pandemic: A Retrospective Endoscopic Study in Japan

Kanako Kishi, Norihisa Ishimura, Yuri Ebisutani, Eiko Okimoto et autres

, and waist circumference increased significantly. Conclusion During the COVID-19 pandemic, the use of acid-suppressive agents and the prevalence of endoscopically diagnosed RE increased, which may be associated with an increased BMI, waist circumference, and diaphragmatic hiatus size, thus indicating the contribution …

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Clinical Features of Invasive Gastric Cancer Developed After Helicobacter pylori Eradication During Regular Endoscopic Surveillance

Akiko Sasaki, Junko Fujisaki, Masaaki Kobayashi, Ken Namikawa et autres

OBJECTIVES: Gastric cancer (GC) may be diagnosed after Helicobacter pylori eradication, sometimes with submucosal invasion; however, its clinical features on regular endoscopic surveillance remain unclear. This study evaluated invasive GC's characteristics after H. pylori eradication during regular endoscopic surveillance by comparing them …

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Negative Association between the Occurrence of Esophageal Candidiasis and Reflux Esophagitis

Kyoichi Adachi, Eiko Okimoto, Utae Sakamoto, Yuko Matsubara et autres

Objective Reflux esophagitis (RE) is caused by gastroesophageal acid reflux, whereas the heterotopic gastric mucosa (HGM) of the cervical esophagus often shows acid secretion. This study investigated whether an intra-esophageal acidic condition in patients with RE or HGM prevents the occurrence of …

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Potentially Causal Associations Between Extensive Gastric Atrophy and Esophageal Squamous Cell Carcinoma: A Nationwide Retrospective Cohort Study in Japan

Kenta Watanabe, Sho Fukuda, Dai Kubota, Nobutake Yamamichi et autres

OBJECTIVES: A potential association between esophageal squamous cell carcinoma (ESCC) and gastric atrophy (GA) has been reported. However, most published studies have used case-control designs, leading to selection bias. This study aimed to investigate the causal association between ESCC and GA using …

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Mucosal Atrophy of the Fornix as an Important Endoscopic Finding for an Autoimmune Gastritis Diagnosis

Kyoichi Adachi, Eiko Okimoto, Yuri Ebisutani, Yuko Matsubara et autres

Objective This study investigated the significance of diagnosing an endoscopic atrophic pattern of the fornix in autoimmune gastritis (AIG). Materials Of 10,608 individuals (men/women: 6,551/4,057) who underwent an esophagogastroduodenal endoscopy (EGD) examination between April 2016 and March 2022 for a medical checkup, …

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Prevalence of gastric epithelial neoplasm of fundic-gland mucosa lineage diagnosed by medical checkup findings and time-course changes

Eiko Okimoto, Norihisa Ishimura, Kyoichi Adachi, Yuri Ebisutani et autres

Background This study was performed to investigate the prevalence of gastric epithelial neoplasm of fundic-gland mucosa lineage (GEN-FGML) and time-course changes in endoscopic findings in affected subjects who underwent an esophagogastroduodenoscopy (EGD) examination as part of an annual checkup.Methods A total of …

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Effectiveness of Artificial Intelligence in Screening Esophagogastroduodenoscopy

Kyoichi Adachi, Yuri Ebisutani, Yuko Matsubara, Eiko Okimoto et autres

Background: This retrospective study investigated the usefulness of the EW10-EG01 artificial intelligence (AI) application for screening esophagogastroduodenoscopy (EGD). Methodology: A total of 7,655 subjects (4,863 men, 2,792 women; mean age 54.9±10.1 years) who underwent EGD during a medical checkup were enrolled in …

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Age distribution and risk factors for Barrett's esophagus by sex at health check-up settings in Japan

Sho Fukuda, Kenta Watanabe, Dai Kubota, Nobutake Yamamichi et autres

BACKGROUND: Given the high prevalence of esophageal adenocarcinoma and Barrett's esophagus (BE), a precancerous lesion, among males, it is important to understand the characteristics of BE by sex to develop an effective endoscopic surveillance program in Japan. The present study examined the …

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Cancer risk by length of Barrett’s esophagus in Japanese population: a nationwide multicenter retrospective cohort study

Sho Fukuda, Kenta Watanabe, Dai Kubota, Nobutake Yamamichi et autres

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Novel Endoscopic Findings of Lesions with a Short White Hair-like Appearance in the Lower Esophagus

Kyoichi Adachi, Eiko Okimoto, Yuri Ebisutani, Kanako Kishi et autres

Objective The presence of a short white hair-like appearance in the lower esophagus has recently been noted during esophagogastroduodenoscopy (EGD) at our institution. Histological findings showed that this formation was a spiked protrusion of the esophageal papilla. The results regarding the prevalence …

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