Prevalence of gastric epithelial neoplasm of fundic-gland mucosa lineage diagnosed by medical checkup findings and time-course changes
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Le résumé fourni par la source
Background This study was performed to investigate the prevalence of gastric epithelial neoplasm of fundic-gland mucosa lineage (GEN-FGML) and time-course changes in endoscopic findings in affected subjects who underwent an esophagogastroduodenoscopy (EGD) examination as part of an annual checkup.Methods A total of 39,292 EGD examinations (25,228 men, 14,034 women; mean age: 53.6 years) were performed between April 2016 and March 2024. The prevalence of GEN-FGML was analyzed, and time-course changes noted in endoscopic findings of diagnosed tumors were investigated by comparison with previous endoscopic images.Results During the study period, we identified 19 patients with 20 GEN-FGML diagnosed based on endoscopic and histological results, with a prevalence of 0.048%. Prevalence was not different between Helicobacter pylori-uninfected and -eradicated cases (0.050% and 0.051%, respectively). Endoscopy findings of 16 of these tumors for which time-course changes could be investigated (median observation period: 8.5 years) showed that 15 were unchanged in size in comparison with previous EGD findings, while one showed enlargement. In addition, three lesions diagnosed after H. pylori eradication were unchanged in size compared to before eradication.Conclusions The prevalence of GEN-FGML by screening EGD was 0.048%, with prevalence not different between H. pylori-uninfected and -eradicated subjects. Enlargement over time was not observed in almost all cases, and H. pylori infection status was considered not to influence changes in tumor size.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Prevalence of gastric epithelial neoplasm of fundic-gland mucosa lineage diagnosed by medical checkup findings and time-course changes
- Date Crossref
- 23/04/2025
- Éditeur
- Informa UK Limited
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Shimane Prefectural Institute of Public Health and Environmental Sciences pays non établi dans la noticeOrganisme public
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Shimane University Second Department of Internal Medicine pays non établi dans la noticeUniversité ou école supérieure
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Matsudo City Hospital pays non établi dans la noticeÉtablissement de santé
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Matsue Red Cross Hospital Department of Pathology pays non établi dans la noticeÉtablissement de santé
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Health Center pays non établi dans la noticeÉtablissement de santé
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Matsue Municipal Hospital Department of Pathology pays non établi dans la noticeÉtablissement de santé
Shimane Prefectural Institute of Public Health and Environmental Sciences, Second Department of Internal Medicine — Shimane University et Matsudo City Hospital, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.