Ivanov Aa

NK cell activity in the tumor microenvironment

A. V. Kuznetsova, Ksenia А. Glukhova, Igor P. Beletsky, Ivanov Aa

The formation of an immunosuppressive tumor microenvironment (TME) impairs natural killer (NK) cell infiltration and persistence within tumor tissue and significantly diminishes NK-mediated cytotoxicity. This presents a substantial barrier to the efficacy of NK cell therapy in solid tumors. Current strategies aim …

ru, mn, fi (code pays fourni par la source)

Induction of Periodontal Endogenous Regeneration by 3D Bioscaffolds

Ivanov Aa, О. П. Попова, A. V. Kuznetsova, Nina N. Butorina et autres

ru, mn (code pays fourni par la source)

Effects of ECM Components on Periodontal Ligament Stem Cell Differentiation Under Conditions of Disruption of Wnt and TGF-β Signaling Pathways

A. V. Kuznetsova, О. П. Попова, Tamara I. Danilova, Andrey V. Latyshev et autres

Periodontitis is accompanied by inflammation that causes dysregulation of the Wnt/β-catenin and TGF-β signaling pathways. This leads to a violation of the homeostasis of periodontal tissues. Components of the extracellular matrix (ECM) are an important part of biomaterials used for the repair …

ru (code pays fourni par la source)

Induction of periodontal endogenous regeneration by 3D bioscaffolds

Ivanov Aa, О. П. Попова, A. V. Kuznetsova, Nina N. Butorina et autres

Contemporary Approaches to Immunotherapy of Solid Tumors

A. V. Kuznetsova, Ksenia А. Glukhova, О. П. Попова, Igor P. Beletsky et autres

In recent years, the arrival of the immunotherapy industry has introduced the possibility of providing transformative, durable, and potentially curative outcomes for various forms of malignancies. However, further research has shown that there are a number of issues that significantly reduce the …

ru, fi (code pays fourni par la source)

Influence of Extracellular Matrix Components on the Differentiation of Periodontal Ligament Stem Cells in Collagen I Hydrogel

Ivanov Aa, A. V. Kuznetsova, О. П. Попова, Tamara I. Danilova et autres

Regeneration of periodontal tissues requires an integrated approach to the restoration of the periodontal ligament, cementum, and alveolar bone surrounding the teeth. Current strategies in endogenous regenerative dentistry widely use biomaterials, in particular the decellularized extracellular matrix (dECM), to facilitate the recruitment …

ru (code pays fourni par la source)

Endogenous Regeneration of Alveolar Bone by Decellularized Tooth Matrix

Alexander V. Latyshev, Tamara I. Danilova, A. V. Kuznetsova, О. П. Попова et autres

ru (code pays fourni par la source)

Current Principles, Challenges, and New Metrics in pH-Responsive Drug Delivery Systems for Systemic Cancer Therapy

Roman A. Verkhovskii, Ivanov Aa, Екатерина Владимировна Ленгерт, Ksenia A. Tulyakova et autres

The paradigm of drug delivery via particulate formulations is one of the leading ideas that enable overcoming limitations of traditional chemotherapeutic agents. The trend toward more complex multifunctional drug carriers is well-traced in the literature. Nowadays, the prospectiveness of stimuli-responsive systems capable …

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Decellularized Matrix Induced Spontaneous Odontogenic and Osteogenic Differentiation in Periodontal Cells

Ivanov Aa, Tamara I. Danilova, A. V. Kuznetsova, О. П. Попова et autres

The regeneration of periodontal tissues is a decisive factor in the treatment of periodontitis. Currently, to achieve complete periodontal regeneration, many studies have evaluated the effectiveness of decellularized tissue-engineered constructs on periodontal regeneration. We studied the possibilities of osteogenic and odontogenic differentiation …

ru (code pays fourni par la source)

Endogenous regeneration of alveolar bone by decellularized tooth matrix

Andrey V. Latyshev, Tamara I. Danilova, A. V. Kuznetsova, О. П. Попова et autres

Pancreatic ductal adenocarcinoma: tumor microenvironment and problems in the development of novel therapeutic strategies

A. V. Kuznetsova, О. П. Попова, Dmitry Nikolayevich Panchenkov, Т. G. Dyuzheva et autres

ru (code pays fourni par la source)

Is there a claudin-low phenotype of breast cancer?

О. П. Попова, A. V. Kuznetsova, S. Yu. Bogomazova, Ivanov Aa

The novel molecular subtype of breast cancer (BC), named "claudin-low", was described in 2007. It was characterized by the consistently low expression of genes involved in the formation of epithelial tight junctions in combination with the high activation of genes associated with …

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