Contemporary Approaches to Immunotherapy of Solid Tumors
Rattachement africain : ru, fi. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
In recent years, the arrival of the immunotherapy industry has introduced the possibility of providing transformative, durable, and potentially curative outcomes for various forms of malignancies. However, further research has shown that there are a number of issues that significantly reduce the effectiveness of immunotherapy, especially in solid tumors. First of all, these problems are related to the protective mechanisms of the tumor and its microenvironment. Currently, major efforts are focused on overcoming protective mechanisms by using different adoptive cell therapy variants and modifications of genetically engineered constructs. In addition, a complex workforce is required to develop and implement these treatments. To overcome these significant challenges, innovative strategies and approaches are necessary to engineer more powerful variations of immunotherapy with improved antitumor activity and decreased toxicity. In this review, we discuss recent innovations in immunotherapy aimed at improving clinical efficacy in solid tumors, as well as strategies to overcome the limitations of various immunotherapies.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Contemporary Approaches to Immunotherapy of Solid Tumors
- Date Crossref
- 19/06/2024
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Moscow State University of Medicine and Dentistry Laboratory of Molecular and Cellular Pathology pays non établi dans la noticeUniversité ou école supérieure
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Ministry of Health of the Russian Federation pays non établi dans la noticeOrganisme public
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Koltzov Institute of Developmental Biology pays non établi dans la noticeStructure de recherche
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Aalto University Onni Biotechnologies Ltd. pays non établi dans la noticeUniversité ou école supérieure
Laboratory of Molecular and Cellular Pathology — Moscow State University of Medicine and Dentistry, Ministry of Health of the Russian Federation et Koltzov Institute of Developmental Biology, avec 1 autre affiliation.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.