Rania M. Abdelsalam

Empagliflozin Dampens Doxorubicin-Induced Chemobrain in Rats: The Possible Involvement of Oxidative Stress and PI3K/Akt/mTOR/NF-κB/TNF-α Signaling Pathways

Rania M. Abdelsalam, Hatem W Hamam, Noha M Eissa, Ayman E. El-Sahar et autres

Égypte, es (code pays fourni par la source)

Cinnamic acid mitigates methotrexate-induced lung fibrosis in rats: comparative study with pirfenidone

Eman Abdalhameid, Enas A. Abd El‐Haleim, Rania M. Abdelsalam, Gehan S. Georgy et autres

PURPOSE: Lung fibrosis is a heterogeneous lung condition characterized by excessive accumulation of scarred tissue, leading to lung architecture destruction and restricted ventilation. The current work was conducted to examine the probable shielding influence of cinnamic acid against lung fibrosis induced by …

Égypte (code pays fourni par la source)

Lactoferrin averts neurological and behavioral impairments of thioacetamide-induced hepatic encephalopathy in rats via modulating HGMB1/TLR-4/MyD88/Nrf2 pathway

Reham M. Essam, Mariam A. Saadawy, Mahitab Gamal, Rania M. Abdelsalam et autres

Égypte (code pays fourni par la source)

Targeting HMGB1/PI3K/Akt and NF-κB/Nrf-2 signaling pathways by vildagliptin mitigates testosterone-induced benign prostate hyperplasia in rats

Ayman E. El-Sahar, Nadine Bekhit, Noha M. Eissa, Rania M. Abdelsalam et autres

Égypte (code pays fourni par la source)

Nanoformulated Recombinant Human Myelin Basic Protein and Rituximab Modulate Neuronal Perturbations in Experimental Autoimmune Encephalomyelitis in Mice

Muhammed A. Saad, Noha M Eissa, M Ahmed, Aliaa Nabil ElMeshad et autres

Introduction: Rituximab (RTX) and recombinant human myelin basic protein (rhMBP) were proven to be effective in ameliorating the symptoms of multiple sclerosis (MS). In this study, a nanoformulation containing rhMBP with RTX on its surface (Nano-rhMBP-RTX) was prepared and investigated in comparison …

Égypte, nz, ae (code pays fourni par la source)

Correction to: Phosphodiesterase (PDE) III inhibitor, Cilostazol, improved memory impairment in aluminum chloride-treated rats: modulation of cAMP/CREB pathway

Mona Khalifa, Rania M. Abdelsalam, Marwa M. Safar, Hala F. Zaki

Égypte (code pays fourni par la source)

Phosphodiesterase (PDE) III inhibitor, Cilostazol, improved memory impairment in aluminum chloride-treated rats: modulation of cAMP/CREB pathway

Mona Khalifa, Rania M. Abdelsalam, Marwa M. Safar, Hala F. Zaki

The most prevalent type of dementia is Alzheimer's disease (AD), which is currently incurable. Existing treatments for Alzheimer's disease, such as acetylcholinesterase inhibitors, are only effective for symptom relief. Disease-modifying medications for Alzheimer's disease are desperately required, given the enormous burdens that …

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Linagliptin attenuates thioacetamide-induced hepatic encephalopathy in rats: Modulation of C/EBP-β and CX3CL1/Fractalkine, neuro-inflammation, oxidative stress and behavioral defects

Yosra A Hussien, Dina F. Mansour, Somaia A. Nada, Sahar S. Abd El‐Rahman et autres

Égypte (code pays fourni par la source)

Dapagliflozin diminishes memory and cognition impairment in Streptozotocin induced diabetes through its effect on Wnt/β-Catenin and CREB pathway

Hala El-Safty, Ashraf A. Ismail, Rania M. Abdelsalam, Ayman E. El-Sahar et autres

Égypte (code pays fourni par la source)

The herbal preparation STW 5 affects serotonergic pathways in the brain and colon as well as stress parameters in experimental irritable bowel syndrome

Nehal G. gamal, Rania M. Abdelsalam, Laila N. Gadelrub, Omar A. Ahmed‐Farid et autres

BACKGROUND: Exposure to stress has been related to disturbance in 5-hydroxytryptamine (5-HT) signaling in the brain-gut axis and is considered as a major predisposing factor for the development of irritable bowel syndrome (IBS). The present study aimed to investigate the possible involvement …

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In Vivo Investigation of the Ameliorating Effect of Tempol against MIA-Induced Knee Osteoarthritis in Rats: Involvement of TGF-β1/SMAD3/NOX4 Cue

Hagar B. Abo-Zalam, Rania M. Abdelsalam, Rehab F. Abdel‐Rahman, Mohamed F. Abd‐Ellah et autres

Osteoarthritis (OA) is a complex disease characterized by structural, functional, and metabolic deteriorations of the whole joint and periarticular tissues. In the current study, we aimed to investigate the possible effects of tempol on knee OA induced by the chemical chondrotoxic monosodium …

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Protective effect of cannabinoids on gastric mucosal lesions induced by water immersion restrain stress in rats.

Rania Salama Elgohary, Rania M. Abdelsalam, Omar ME Abdel-Salam, Mahmoud M. Khattab et autres

OBJECTIVES: This study aimed to determine the impact of cannabinoid agonists and antagonists on the mucosal lesion progress in the stomach induced by water-immersion restraint stress (WIRS). MATERIALS AND METHODS: Rats subjected to WIRS for 4 hr were treated with Dimethyl sulfoxide …

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