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Current practice and short-term outcomes of therapeutic mammaplasty in the international TeaM multicentre prospective cohort study

48Citations signalées — pas une note de qualité
82Institutions déclarées
2Pays d’affiliation déclarés

Résumé fourni par la source

BACKGROUND: Therapeutic mammaplasty, which combines breast reduction and mastopexy techniques with tumour excision, may extend the boundaries of breast-conserving surgery and improve outcomes for patients, but current practice is unknown and high-quality outcome data are lacking. This prospective multicentre cohort study aimed to explore the practice and short-term outcomes of the technique. METHODS: Consecutive patients undergoing therapeutic mammaplasty at participating centres between 1 September 2016 and 30 June 2017 were recruited to the study. Demographic, preoperative, operative, oncological and complication data were collected. The primary outcome was unplanned reoperation for complications within 30 days of surgery. Secondary outcomes included re-excision rates and time to adjuvant therapy. RESULTS: Overall, 880 patients underwent 899 therapeutic mammaplasty procedures at 50 centres. The most common indications were avoidance of poor cosmetic outcomes associated with standard breast-conserving surgery (702 procedures, 78·1 per cent) or avoidance of mastectomy (379, 42·2 per cent). Wise-pattern skin incisions were the most common (429 of 899, 47·7 per cent), but a range of incisions and nipple-areola pedicles were used. Immediate contralateral symmetrization was performed in one-third of cases (284 of 880, 32·3 per cent). In total, 205 patients (23·3 per cent) developed a complication, but only 25 (2·8 per cent) required reoperation. Median postoperative lesion size was 24·5 (i.q.r. 16-38) mm. Incomplete excision was seen in 132 procedures (14·7 per cent), but completion mastectomy was required for only 51 lesions (5·7 per cent). Median time to adjuvant therapy was 54 (i.q.r. 42-66) days. CONCLUSION: Therapeutic mammaplasty is a safe and effective alternative to mastectomy or standard breast-conserving surgery. Further work is required to explore the impact of the technique on quality of life, and to establish cost-effectiveness.

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Contrôle bibliographique ouvert

DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.

Titre Crossref
Current practice and short-term outcomes of therapeutic mammaplasty in the international TeaM multicentre prospective cohort study
Date Crossref
22/08/2018
Éditeur
Oxford University Press (OUP)
Type
journal-article

Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude et ne compte pas comme une seconde source scientifique indépendante.

Institutions déclarées

Royal Marsden NHS Foundation TrustAiredale General HospitalAt BristolUniversity of LeicesterNottingham University Hospitals NHS TrustNorth Bristol NHS TrustRoyal Liverpool and Broadgreen University Hospital NHS TrustLeeds Teaching Hospitals NHS TrustSt James's University HospitalUniversity of BristolBarts Health NHS TrustWhipps Cross University HospitalUniversity Hospitals Birmingham NHS Foundation TrustQueen Elizabeth Hospital BirminghamRoyal Devon & Exeter NHS Foundation TrustRoyal Victoria InfirmaryNewcastle upon Tyne Hospitals NHS Foundation TrustManchester University NHS Foundation TrustWythenshawe HospitalOxford University Hospitals NHS TrustPennine Acute Hospitals NHS TrustAberdeen Royal InfirmaryNHS GrampianCambridge University Hospitals NHS Foundation TrustAddenbrooke's HospitalBelfast Health and Social Care TrustUniversity of UlsterBelfast City HospitalSouthmead HospitalFederico II University HospitalUniversity of Naples Federico IIUniversity Hospitals Sussex NHS Foundation TrustHull and East Yorkshire Hospitals NHS TrustCastle Hill HospitalChesterfield Royal Hospital NHS Foundation TrustDarent Valley HospitalDartford And Gravesham NHS TrustEast Cheshire NHS TrustNHS LothianWestern General HospitalForth Valley Royal HospitalNHS Forth ValleyNHS Greater Glasgow and ClydeGartnavel General HospitalGlenfield HospitalTorbay and South Devon NHS Foundation TrustGloucestershire Hospitals NHS Foundation TrustGood Hope HospitalHeart of England NHS Foundation TrustWexham Park HospitalFrimley Health NHS Foundation TrustHomerton University Hospital NHS Foundation TrustLincoln County HospitalUnited Lincolnshire Hospitals NHS TrustPilgrim HospitalLuton and Dunstable HospitalMid Yorkshire Hospitals NHS TrustMilton Keynes Hospital NHS Foundation TrustMusgrove Park HospitalTaunton & Somerset NHS Foundation TrustSomerset NHS Foundation TrustNHS TaysideNorthern Lincolnshire and Goole Hospitals NHS Foundation TrustPeterborough City HospitalHywel Dda University Health BoardPrince Philip HospitalPrincess Alexandra Hospital NHS TrustBolton NHS Foundation TrustRoyal Bolton HospitalRoyal Hampshire County HospitalHampshire Hospitals NHS Foundation TrustCTO Andrea AlesiniSt Bartholomew's HospitalWest Hertfordshire Hospitals NHS TrustSt George’s University Hospitals NHS Foundation TrustUlster HospitalSouth Eastern Health and Social Care TrustSt Helens and Knowsley Teaching Hospitals NHS TrustWhiston HospitalWirral University Teaching Hospital NHS Foundation TrustWorcestershire Acute Hospitals NHS TrustYork Teaching Hospital NHS Foundation Trust

Une affiliation ne permet pas de déduire la nationalité d’un auteur.

Sujets associés

Breast Implant and ReconstructionBreast Cancer Treatment StudiesBody Contouring and Surgery

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