Clare Fowler

Endotracheal surfactant for infants with life-threatening bronchiolitis (BESS): a randomised, blinded, sham-controlled, phase 2 trial

Malcolm Gracie Semple, Malcolm G Semple, Chloe Donohue, Laura Price et autres

BACKGROUND: Bronchiolitis is a common viral respiratory disease of infants, with severity ranging from mild symptoms, such as coryza and feeding difficulties, to fulminant respiratory failure. Endotracheal administration of exogenous surfactant has been shown in small studies to improve gas exchange in …

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Safe and transparent introduction and evaluation of targeted axillary dissection in patients with node-positive breast cancer undergoing primary surgery: international consensus process

Shelley Potter, Henry J. Cain, Edward St John, Peter James Barry et autres

BACKGROUND: Axillary node clearance is the current standard of care in patients with node-positive breast cancer undergoing primary surgery, despite a lack of evidence to demonstrate survival benefit and high rates of life-changing morbidity. Targeted axillary dissection (TAD) may be a safe …

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Wire- and radiofrequency identification tag-guided localization of impalpable breast lesions: iBRA-NET localization study

James Harvey, Jenna L. Morgan, Simon Lowes, Robert A. Milligan et autres

A national cohort ideal stage 2a/2b study comparing the safety and effectiveness of Wire- and RFID -guided localisation for impalpable breast lesions.

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Bridging pre-surgical endocrine therapy for breast cancer during the COVID-19 pandemic: outcomes from the B-MaP-C study

Rajiv Dave, Beatrix Elsberger, Vicky P. Taxiarchi, Ashu Gandhi et autres

PURPOSE: The B-MaP-C study investigated changes to breast cancer care that were necessitated by the COVID-19 pandemic. Here we present a follow-up analysis of those patients commenced on bridging endocrine therapy (BrET), whilst they were awaiting surgery due to reprioritisation of resources. …

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Local breast recurrence after breast conserving surgery

Nadeem Al-Khafaji, Rebecca Llewellyn-Bennett, Clare Fowler, Sarah Vestey et autres

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Neo‐Adjuvant chemotherapy and its affects to the axilla—Can we safely downgrade axillary surgery to mirror the approach in the breast

Jeremy Batt, Alice Chambers, Asmaa Al‐Allak, Sarah Vestey et autres

The use of neo-adjuvant chemotherapy (NACT) to downgrade surgery in the breast from mastectomy to breast-conserving surgery is well-established. In certain patients, the use of adjuvant axillary radiotherapy can be safe and effective in place of axillary node clearance. What remains less …

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Symptomatic Breast Cancers and Why Breast Pain May not Always Need Clinical Review

Nicola Cook, Jeremy Batt, Clare Fowler

IntroductionBreast cancer is the most common cancer in the UK and approximately 55,000 new cases are diagnosed each year (1, 2).A typical District General Hospital will see between six thousand and eight thousand new patients a year with between four hundred and …

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P132: Neoadjuvant chemotherapy and its effects to the axilla - Can we safely downgrade axillary surgery to mirror the approach in the breast

Jeremy Batt, Alice Chambers, Asmaa Al‐Allak, Clare Fowler

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Therapeutic mammaplasty is a safe and effective alternative to mastectomy with or without immediate breast reconstruction

Shelley Potter, Adam Trickey, Tim Rattay, Rachel L. O’Connell et autres

BACKGROUND: Therapeutic mammaplasty (TM) may be an alternative to mastectomy, but few well designed studies have evaluated the success of this approach or compared the short-term outcomes of TM with mastectomy with or without immediate breast reconstruction (IBR). Data from the national …

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Multicentre prospective observational study evaluating recommendations for mastectomy by multidisciplinary teams

Jagdeep K Singh, Sekhar Marla, Daniel William Rea, M. Hallissey et autres

BACKGROUND: Recommendations for mastectomy by multidisciplinary teams (MDTs) may contribute to variation in mastectomy rates. The primary aim of this multicentre prospective observational study was to describe current practice in MDT decision-making for recommending mastectomy. A secondary aim was to determine factors …

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Symptomatic Breast Cancers and Why Breast Pain May Not Always Need Clinical Review

Jeremy Batt, Nicola Cook, Clare Fowler

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P085. The use of the Klinitray: Is it cost-effective?

Mina Awad, Darren Leonard Scroggie, Nikki Green, Richard Hunt et autres

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