Bruno Jorge Pereira

Obesogenic Dysregulation of Human Periprostatic Adipose Tissue Promotes the Viability of Prostate Cells and Reduces Their Sensitivity to Docetaxel and Cabazitaxel

Mariana Feijó, Lara R. S. Fonseca, Gonçalo Catarro, Cátia V. Vaz et autres

BACKGROUND: Periprostatic adipose tissue (PPAT) has been shown to play a significant role in prostate cancer (PCa) development and progression. This relationship is further exacerbated by obesity, as PPAT-secreted factors increase PCa aggressiveness and have also been implicated in chemotherapy resistance. Therefore, …

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Hyperthermic vs normothermic mitomycin C for intermediate-risk NMIBC: a real-world retrospective cohort study

José Pereira, Ana Maria Ferreira, Rita Marques, Mário Lourenço et autres

INTRODUCTION: Hyperthermic intravesical chemotherapy (HIVeC) with mitomycin C (MMC) is an emerging strategy in the management of intermediate-risk non-muscle-invasive bladder cancer (Ir-NMIBC). By combining chemotherapy with controlled hyperthermia (43°C), this approach aims to enhance drug absorption, increase cytotoxicity, and stimulate immune activation, …

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Exogenous uromodulin and tubular responses in a model of oxalate-induced kidney injury

Larissa de Araújo, N. Pina-Lopes, Bruno Jorge Pereira, Juliana da Costa Santos Pessoa et autres

This study sheds light on the potential role of exogenous uromodulin in modulating tubular responses to oxalate-induced kidney injury. By exploring its influence on epithelial stress, inflammation, and protein trafficking, these findings provide a more comprehensive understanding of uromodulin's function beyond its …

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COCO VERDE: CARACTERIZAÇÃO FÍSICO-QUÍMICA E ELABORAÇÃO DE UMA MOUSSE

Leonardo Moraes Amorim, Larissa Alves Ramos, Bruno Jorge Pereira, Ewerton Carvalho de Souza et autres

O coco verde é um fruto muito apreciado, sendo que sua água, denominada água de coco, costuma ser consumida in natura e, muitas vezes, a polpa do coco verde, por mais que seja um alimento nutritivo, é descartada, juntamente com a sua …

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Supratrigonal systectomy: last line treatment for radiation-induced hemorrhagic cystitis

José Pereira, Mário Lourenço, Paulo Conceição, Ricardo Godinho et autres

INTRODUCTION: Hemorrhagic cystitis is defined by the presence of hematuria, lower urinary tract symptoms and cystoscopy findings indicative of underlying urothelial damage. It is common in patients with prior radiotherapy for pelvic malignancies. The severity of the bleeding can vary from mild …

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Dermatoses neutrophiliques associées aux syndromes myélodysplasiques : une étude cas-témoins

C. Soavi, F. Chasset, C. Grolleau-Raoux, M. Battistella et autres

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Endocrine-disrupting chemicals as prostate carcinogens

Mariana Feijó, Tiago M. A. Carvalho, Lara R. S. Fonseca, Cátia V. Vaz et autres

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A0141 – Results of testicular preservation in testicular torsion: A study comparing albuginectomy with tunica vaginalis flap and orchidopexy

Marcos Bróglio, Bruno Jorge Pereira, Rafael Ribeiro Zanotti, André Pereira Matos et autres

Efficacy of valaciclovir in preventing herpes zoster in patients receiving anifrolumab

Ludovic Tréfond, François Chasset, M. Jachiet, C. Bulaï Livideanu et autres

International audience

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ENSAIOS PRELIMINARES PARA DETERMINAÇÃO DA RESISTIVIDADE ELÉTRICA DO PA12 FABRICADO POR POWDER BED FUSION

Joyce Mara Brandão Maia, Bruno Caetano dos Santos Silva, Iuri Muniz Pepe, Bruno Jorge Pereira

Development and external validation of the ‘Global Surgical-Site Infection’ (GloSSI) predictive model in adult patients undergoing gastrointestinal surgery

McLean KA, Knight SR, Nina M. Clark, Adesoji Ademuyiwa et autres

Abstract Background Identification of patients at high risk of surgical-site infections may allow surgeons to minimize associated morbidity. However, there are significant concerns regarding the methodological quality and transportability of models previously developed. The aim of this study was to develop a …

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Salvage cryotherapy for prostate cancer

D. Brito, José Pereira, Ana Maria Ferreira, Mário Lourenço et autres

BACKGROUND: Most men diagnosed with prostate cancer will be candidates for active treatment and 20 to 50% of patients treated with organ preserving strategies recur within the prostate. Optimal treatment of recurrence is controversial. Prostate cryosurgery has been increasingly used as primary, …

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