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Accès ouvert déclaré 2014 article

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

891Citations signalées, ce qui n’est pas une note de qualité
161Institutions déclarées
19Pays d’affiliation déclarés

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Le résumé fourni par la source

The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. Organized into Working Groups that tackle questions in neuroscience, genetics, and medicine, ENIGMA studies have analyzed neuroimaging data from over 12,826 subjects. In addition, data from 12,171 individuals were provided by the CHARGE consortium for replication of findings, in a total of 24,997 subjects. By meta-analyzing results from many sites, ENIGMA has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected. ENIGMA's first project was a genome-wide association study identifying common variants in the genome associated with hippocampal volume or intracranial volume. Continuing work is exploring genetic associations with subcortical volumes (ENIGMA2) and white matter microstructure (ENIGMA-DTI). Working groups also focus on understanding how schizophrenia, bipolar illness, major depression and attention deficit/hyperactivity disorder (ADHD) affect the brain. We review the current progress of the ENIGMA Consortium, along with challenges and unexpected discoveries made on the way.

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Le contrôle bibliographique ouvert

DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.

Titre Crossref
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data
Date Crossref
08/01/2014
Éditeur
Springer Science and Business Media LLC
Type
journal-article

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Les institutions déclarées

University of Southern CaliforniaUniversity of California, Los AngelesQIMR Berghofer Medical Research InstituteRadboud University NijmegenRadboud University Medical CenterCentre National de la Recherche ScientifiqueInstitut PasteurDélégation Paris 7Université Paris CitéSorbonne Paris CitéGènes, synapses et cognitionKing's College LondonUniversity of OsloKarolinska InstitutetDalhousie UniversityRoyal College of Surgeons in IrelandMcGill UniversityTexas Biomedical Research InstituteUniversity of PittsburghNorthwestern UniversityNorthwestern UniversityNorthwestern MedicineUniversity of IowaOslo University HospitalUniversität GreifswaldThe University of SydneyScottish and Southern Energy (United Kingdom)University of EdinburghUniversity Hospital Carl Gustav CarusUCLA HealthNeurobehavioral SystemsMax Planck Institute of PsychiatryACTRoyal Edinburgh HospitalAmsterdam NeuroscienceUniversity Medical Center UtrechtMassachusetts General HospitalCenter for Human GeneticsHarvard UniversityDutch Expert Centre for ScreeningKarakterVavilov Institute of General GeneticsUniversity of New MexicoMind Research NetworkOllscoil na Gaillimhe – University of GalwayCardiff UniversityCentre for Addiction and Mental HealthUniversity of TorontoStanford UniversityUniversity of BergenUniversity of BonnForschungszentrum JülichUniversity of BaselCentre Hospitalier Universitaire Sainte-JustineKings Health PartnersUniversidad de CantabriaCentro de Investigación Biomédica en Red de Salud MentalMarqués de Valdecilla University HospitalUniversité Libre de BruxellesErasmus HospitalThe University of QueenslandTrinity College DublinAthinoula A. Martinos Center for Biomedical ImagingCharité - Universitätsmedizin BerlinMax Planck Institute for PsycholinguisticsIndiana University School of MedicineIndiana University – Purdue University IndianapolisThe University of Texas at San Antonio Health Science CenterSouth Texas Veterans Health Care SystemThe University of Texas Health Science Center at HoustonIcahn School of Medicine at Mount SinaiUniversity of RegensburgTrinity CollegeCommissariat à l'Énergie Atomique et aux Énergies AlternativesUniversity of VermontHaukeland University HospitalHartford HospitalYale UniversityUniversity of OxfordGerman Center for Neurodegenerative DiseasesHeidelberg UniversityUniversity Hospital HeidelbergCentral Institute of Mental HealthUniversity of GöttingenUniversity of PennsylvaniaMcMaster UniversityUniversity College LondonUniversity Medical Center GroningenUniversity of GroningenDiakonhjemmet HospitalUniversitätsmedizin GreifswaldUniversity of Maryland, BaltimoreOakland UniversityMayo Clinic in ArizonaMayo Clinic in FloridaWellcome Centre for Integrative NeuroimagingNational Health ServiceSouth London and Maudsley NHS Foundation TrustCentre for Mental HealthUNSW SydneyNeuroscience Research AustraliaShort and Associates (United States)University of GothenburgVanderbilt UniversityUniversity of MissouriBroad InstituteUniversité Paris-SudDélégation Paris 5InsermUnited States Department of Health and Human ServicesNational Institutes of HealthColumbia University Irving Medical CenterNational Human Genome Research InstituteNational Institute of Mental HealthDepartment of Health and Human ServicesNational Institute of Mental HealthUniversity of NottinghamUniversity of MilanUniversity of California, IrvineUniversity of CalgaryDepartment of Health and Aged CareCentre for Healthy Brain AgeingAarhus UniversitySørlandet SykehusNational Imaging FacilityLudwig-Maximilians-Universität MünchenNational Institute on AgingThe University of Western AustraliaUniversity of Minnesota Medical CenterLife & Brain (Germany)Munich Cluster for Systems NeurologyTexas Medical CenterThe University of Texas at AustinUniversity of WarwickStockholm UniversityUmeå UniversityRotman Research InstituteHospital for Sick ChildrenSickKids FoundationAllen Institute for Brain ScienceImaging CenterRTI InternationalPrince of Wales HospitalLaureate Institute for Brain ResearchUniversity of TulsaUniversity of California San DiegoBeth Israel Deaconess Medical CenterHarvard University PressMinneapolis VA Health Care SystemAlzheimer ScotlandUniversity of Cincinnati Medical CenterKing Faisal Specialist Hospital & Research CentreGeorgia State UniversityLeiden University Medical CenterMRC Centre for Regenerative MedicineHumboldt-Universität zu BerlinUniversity of California, San FranciscoErasmus University RotterdamUniversity of ExeterJohnson & Johnson (United States)Janssen (United States)

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Les sujets associés

Functional Brain Connectivity StudiesGenetic Associations and EpidemiologyAdvanced Neuroimaging Techniques and Applications

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