Brenda W.J.H. Penninx

Brain functional dynamics linked to depression and anxiety: cross-sectional and longitudinal associations over 9 years

Julian Gaviria, Guido van Wingen, Rick Jansen, Jennifer S. Labus et autres

ABSTRACT Background Resting-state fMRI (rs-fMRI) co-activation patterns (CAPs) capture recurrent whole-brain states that may index neurobiological substrates of affective psychopathology, but whether their temporal dynamics co-evolve with symptom severity over the naturalistic long-term course of depression and anxiety remains unknown. Methods We …

nl, us (code pays fourni par la source)

Parkinsonism and psychopathology severity in real-world outpatients with schizophrenia: A cross-sectional PRISM study

Joaquín Galvañ, Javier-David López-Moríñigo, Gonzalo Salazar de Pablo, Marta Sepúlveda et autres

es, nl (code pays fourni par la source)

Remote Measurement of Sleep and Physical Activity for Depression Severity Prediction: A Machine Learning Study (Preprint)

Carolin Oetzmann, Nicholas Cummins, Ewan Carr, Yuezhou Zhang et autres

BACKGROUND Remote measurement technologies (RMTs) offer a potential solution for monitoring depression symptoms in situ while reducing reliance on self-report assessments. Sleep and physical activity measures derived from wearable devices may capture behavioural patterns relevant to depressions severity, but their incremental value …

Multilingual lexical feature analysis of spoken language for predicting major depression symptom severity

Anastasiia Tokareva, Judith Dineley, Zoë Firth, Pauline Conde et autres

gb, us, nl, es (code pays fourni par la source)

Atypical energy-related symptoms define biologically distinct subtypes of major depressive disorder

Arvid Harder, Rujia Wang, Jacob Bergstedt, Floris Huider et autres

ABSTRACT Major depressive disorder (MDD) is a complex psychiatric disorder, characterized by a range of mood, cognitive, and neurovegetative symptoms. Current diagnostic criteria treat opposite symptom directions as equivalent; weight gain or loss, and increased or decreased sleep, each count toward a …

se, gb, nl, ee, au, it, us (code pays fourni par la source)

Decomposing neuroanatomical heterogeneity in depression: insights from an ENIGMA major depressive disorder working group study in 5146 individuals

Lukas Sempach, Sarah Ulrich, Stéphanie Bauduin, Jochen Bauer et autres

Abstract The clinical and biological heterogeneity of major depressive disorder (MDD) may reflect the aggregation of different conditions with distinct pathologies under a single diagnostic label. Neuroanatomical heterogeneity in MDD was examined using a harmonized, age- and sex-matched sample from the ENIGMA …

ch, nl, de, it, us, fr, au, gb, es, tr, Afrique du Sud, no, jp, sg (code pays fourni par la source)

Sleep and Activity Patterns in Depression From Wearable Data: Unsupervised Clustering Study

Carolin Oetzmann, Yuezhou Zhang, Nicholas Cummins, Ewan Carr et autres

Background: Efforts to advance our understanding of depression have long been constrained by the disorder's vast symptom heterogeneity and by the reliance on self-report, which offers only a partial view of phenotypic expression. Digital phenotyping provides an opportunity to address these core …

gb, es, nl, dk, us (code pays fourni par la source)

Genetics of major depressive disorder in a homogeneous population with uniform phenotyping

Floris Huider, Yuri Milaneschi, René Pool, Bernardo de A.P.C. Maciel et autres

Abstract Harmonized phenotyping and diverse population-specific studies are crucial for advancing gene discovery in psychiatric genetics. We conducted a genome-wide association (GWAS) mega-analysis of DSM-defined lifetime major depressive disorder (MDD) in 64 941 participants (25.7% cases) from the Dutch BIObanks Netherlands Internet …

nl, au, Afrique du Sud, qa (code pays fourni par la source)

Group, Subgroup and Person‐Specific Longitudinal Associations Between Physical Activity and Affect in Individuals With and Without Depressive and Anxiety Disorders

Noa van Zwieten, George Aalbers, Femke Lamers, Harriëtte Riese et autres

OBJECTIVES: Associations between physical activity and affect (activity-affect dynamics) vary among individuals for which reasons remain unclear. We examined whether such heterogeneity is explained by psychiatric status or sociodemographic, clinical, and ambulatory assessment characteristics. METHODS: Two-week ambulatory assessment data of 300 participants …

nl (code pays fourni par la source)

Interviewer and Respondent Sociodemographic Characteristics, Rapport, and Their Joint Impact on Data Quality in the NESDA Study

Melany Horsfall, Adriaan W. Hoogendoorn, Stasja Draisma, Merijn Eikelenboom et autres

OBJECTIVES: Data quality in face-to-face interviews may be affected by sociodemographic characteristics of interviewers and respondents (age, education, and gender) as well as their (dis)similarity. Similarity in these characteristics may foster rapport, potentially enhancing cooperation and improving data quality. This study examined …

nl (code pays fourni par la source)

The association between outdoor noise and temperature exposure with incident type 2 diabetes, and mediation by sleep and body mass index: A multi-cohort analysis

Noreen Z. Siddiqui, Joreintje D. Mackenbach, Maria G.M. Pinho, Hans Bosma et autres

BACKGROUND: High noise exposure and temperatures may increase type 2 diabetes (T2D) risk by reducing sleep duration and increasing Body Mass Index (BMI). We studied associations between outdoor noise and nighttime temperature exposure with incident T2D in the Dutch population and assessed …

nl, in (code pays fourni par la source)

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.

Jari Lahti, Franziska Ritschel, Dorret I. Boomsma, Christian Dina et autres

Eating disorders and substance use disorders frequently co-occur. Twin studies reveal shared genetic variance between liabilities to eating disorders and substance use, with the strongest associations between symptoms of bulimia nervosa and problem alcohol use (genetic correlation [rg ], twin-based = 0.23-0.53). …

us (code pays fourni par la source)