Sanguinarine Induces ROS ‐Mediated Mitochondrial Dysfunction and Inhibits AKT / GSK3 Signaling to Potentiate Apoptotic Effects in Cutaneous T‐Cell Lymphoma
Shilpa Kuttikrishnan, Muhammad Suleman, Fareed Ahmad, Zahwa Mariyam et autres
Cutaneous T-cell lymphoma (CTCL) is a rare non-Hodgkin lymphoma with limited durable treatment options and poor overall survival, underscoring the need for new therapeutic approaches. Sanguinarine (SNG), a natural benzophenanthridine alkaloid, has demonstrated anticancer activity in several malignancies, but its potential role …
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