GJB2 drives LUAD progression in part via cAMP-mediated M2 macrophage polarization through the PKA-CREB pathway
Yuanhua Liu, Guanghui Liu, Jingjing Mei, J M Li et autres
BACKGROUND: M2 macrophage polarization is a key driver of lung adenocarcinoma (LUAD) progression, yet its underlying regulatory mechanisms remain unclear. The expression pattern and biological function of the gap junction protein GJB2 in LUAD have not been elucidated to date. METHODS: TCGA …
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Respiratory Research