Lulu Ma

The mediating effect role of methylmalonic acid on the association between oxidative balance score and diabetic kidney disease: a cross-sectional study from NHANES 2011–2014

Hongli Yang, Lulu Ma, Lianglan Shen, Wubin Yao et autres

Diabetic kidney disease (DKD) is a prevalent complication of diabetes. Methylmalonic acid (MMA) reflects mitochondrial dysfunction. Oxidative balance score (OBS) assesses the pro-oxidant/anti-oxidant propensity of lifestyle. This study explored the associations of OBS and MMA with the risk of DKD. In this …

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Early Depression Detection in Social Media: Monitoring of Individual Nighttime Dynamics and Large Language Model Analysis

Bo Yu, Zhichang Zhang, Lulu Ma, Jingying Cai

BACKGROUND Depression has become a major global public health challenge, and early intervention is critical for improving patient outcomes. Current depression detection techniques based on social media data (Traditional Risk Detection, TRD) rely heavily on users’ complete historical information, which cannot meet …

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Association between general anaesthesia exposure and neurodevelopment in children with congenital scoliosis at a Chinese tertiary hospital: study protocol for a prospective longitudinal observational cohort study

Ziyi Dai, Yuelun Zhang, Lulu Ma, Jianguo Zhang et autres

Introduction Previous studies have indicated that exposure to anaesthetics has potential neurotoxic effects, particularly in cases of multiple and long-term general anaesthesia. However, there is currently no research exploring the relationship between early anaesthesia and neurological development in children with congenital scoliosis, …

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Early Depression Detection in Social Media: Monitoring of Individual Nighttime Dynamics and Large Language Model Analysis (Preprint)

Bo Yu, Zhichang Zhang, Lulu Ma, Jingying Cai

BACKGROUND Depression has become a major global public health challenge, and early intervention is critical for improving patient outcomes. Current depression detection techniques based on social media data (traditional risk detection) rely heavily on users’ complete historical information, which cannot meet the …

pH-responsive self-assembly of natural saponin glycyrrhizic acid

Jiyang Cai, Yang Liu, Lulu Ma, Sili Liu et autres

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Effects of Total Intravenous Anesthesia and Inhalational Anesthesia on Postoperative Recovery in Patients Undergoing Transsphenoidal Pituitary Surgery:A Systematic Review.

Yu Ying Feng, Yupei Zhang, Yuelun Zhang, Bing Xing et autres

Objective To systematically evaluate the effects of total intravenous anesthesia and inhalational anesthesia on postoperative recovery in patients undergoing transsphenoidal pituitary tumor resection.Methods A comprehensive search was conducted in international biomedical databases including Ovid Medline,Embase,CINAHL(EBSCO),Cochrane Library,and Web of Science,from inception to July …

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OTUD1 inhibits osteoclast differentiation and osteoclastic bone loss through deubiquitinating and stabilizing PRDX1

Xiaoyu Sun, Tong Wu, Shuhong Chen, Zheyu Zhao et autres

Our findings provided the first evidence that OTUD1 suppressed osteoclastogenesis by deubiquitinating PRDX1 and maintaining its stability, thereby offering a promising therapeutic approach for osteoclast-dependent bone diseases.

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Ubiquitin‐Proteasome System in Periodontitis: Mechanisms and Clinical Implications

Yilin Ma, Ru Jia, Shuhong Chen, Jun Ma et autres

The progression of periodontitis, a bacteria-driven inflammatory and bone-destructive disease, involves myriad cellular and molecular mechanisms. Protein regulation significantly influences the pathogenesis and management of periodontitis. However, research regarding its regulatory role in periodontitis remains relatively limited. The ubiquitin-proteasome system (UPS), which …

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Contrasting Effects of Nutrient Addition on Wood Decomposition Rates between Angiosperms and Gymnosperms

Lulu Ma, Zhenhong Hu, Zhuqi Zhao, Xian He et autres

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Isolated unilateral oculomotor palsy caused by pure midbrain infarction: a case report

Zhu-Ling Chen, Shi-Guo Zhu, Rong‐Pei Liu, Lulu Ma et autres

Abstract Background: Multiple etiologies may cause oculomotor nerve palsies. Identification of different etiologies is very important for subsequent treatment. Midbrain infarction is a rare cause of oculomotor nerve palsy. Case presentation: We herein present a case of isolated unilateral oculomotor paresis caused …

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Unveiling hepatotoxicity distinction of coumarin-related compounds from glycosides to aglycones in Fructus Psoraleae by integrating UPLC-Q-TOF-MS and high content analysis

Benyu Liu, Shiming Fang, Kun Zhou, Lulu Ma et autres

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Quantitative Analysis and Stability Study on Iridoid Glycosides from Seed Meal of Eucommia ulmoides Oliver

Lulu Ma, Ning Meng, Benyu Liu, Changjian Wang et autres

As a traditional Chinese medicine, Eucommia ulmoides Oliver (E. ulmoides Oliv.) is an important medicinal plant, and its barks, male flowers, leaves, and fruits have high value of utilization. The seed meal of E. ulmoides Oliv. is the waste residue produced after …

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