Accès ouvert
2025
article
OpenAlex
Ali Mazloum, Sofya G. Feoktistova, Anna Gubaeva, Almaqdad Alsalloum et autres
), leading to defective proinsulin processing, endoplasmic reticulum (ER) stress, and β-cell dysfunction. Current management relies on sulfonylureas or insulin therapy, but these fail to address the underlying genetic defect. Recent research has elucidated the molecular mechanisms of MODY10, including ER stress …
ru
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Accès ouvert
2025
article
OpenAlex
Elena Astakhova, Anna Gubaeva, Daria A. Naumova, Ann Egorova et autres
Flow cytometry is a powerful and widely used tool for the analysis of various cell populations, but its capabilities are severely limited by the need to apply correction of fluorescent signals from near or similar fluorochromes when analyzing multicolor panels. Spectral flow …
ru
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Accès ouvert
2024
article
OpenAlex
Valentin Artemyev, Anna Gubaeva, Anastasiia Iu. Paremskaia, Amina A. Dzhioeva et autres
Gene therapy is a promising approach to the treatment of various inherited diseases, but its development is complicated by a number of limitations of the natural promoters used. The currently used strong ubiquitous natural promoters do not allow for the specificity of …
ru
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