Ancuța Năstac

Is age still a barrier in ventricular tachycardia ablation? A study of safety, efficacy and clinical outcomes in the elderly

Laura Stanciulescu, Ancuța Năstac, Maria Dorobantu

Background Ventricular tachycardia (VT) catheter ablation is an established therapy in patients with structural heart disease (SHD), yet its use in elderly populations remains limited due to concerns regarding procedural risk and outcomes. This study aimed to evaluate the safety, efficacy, and …

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Natural Versus Vaccine-Induced Immunity Against HPV: A Comparative Review of Antibody Response and Cancer Prevention

Bogdan Ghilencea, Bianca Ilinca Moroianu, Ancuța Năstac, Ioana-Stefania Bostan et autres

Human Papillomavirus (HPV) infection is the leading cause of cervical cancer, presenting a significant global health challenge. While natural infection is widespread, the resulting immune response is often characterized by weak, delayed, and type-specific antibody production, offering unreliable protection against reinfection. This …

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Pancreatic Metastases from Clear Cell Renal Cell Carcinoma: Diagnostic Insights from Endoscopic Ultrasound-Guided Fine-Needle Biopsy

Alexandru Constantinescu, Ion Dina, Maria Nedelcu, Vlad Dumitru Băleanu et autres

Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer, accounting for approximately 75-80% of all renal carcinomas, and is often diagnosed incidentally on abdominal imaging, such as abdominal ultrasound or CT scan. Among other types of renal …

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The Role of Ophthalmic Artery Doppler in Predicting Preeclampsia: A Review of the Literature

Nicoleta Gana, Ancuța Năstac, Livia Mihaela Apostol, Iulia Huluță et autres

Background and Objectives: Preeclampsia (PE) complicates 2–8% of pregnancies globally, with a higher incidence in developing countries. This condition poses significant risks to maternal and fetal health, contributing substantially to maternal and perinatal mortality, particularly in cases of early-onset PE, which is …

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Celiac Disease: Diagnostic Advances, Differential Challenges, and Interface with Non-Celiac Gluten Sensitivity

Vlad Ionescu, Alice Elena Ciontu, Gabriel Ianu Ianuș, Vlad Buică et autres

Celiac disease (CeD) is an immune-mediated enteropathy triggered by gluten in genetically susceptible individuals, with a heterogeneous clinical spectrum spanning classical gastrointestinal symptoms, extraintestinal manifestations, and subclinical forms. We synthesize contemporary epidemiology, immunopathogenesis, and the updated 2025 European Society for the Study …

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Toward Earlier Detection: Revisiting Colorectal Cancer Screening Age in the U.S. and Europe

Vlad Buică, Ancuța Năstac, Gina Gheorghe, Teodor Florin Georgescu et autres

Background: Colorectal cancer (CRC) represents one of the leading causes of cancer-related morbidity and mortality globally. Although national screening programs in Europe and the United States have demonstrated success in reducing incidence and death rates among populations aged 50 and above, a …

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Digital Transformation of Medical Services in Romania: Does the Healthcare System Meet the Current Needs of Patients?

Ioana-Marcela PĂCURARU, Ancuța Năstac, Andreea ZAMFIR, Ștefan Busnatu et autres

Background: The digitalization of medical services is promoted as a solution for improving access, quality, and efficiency within healthcare systems. In this context, the study investigates the extent to which digitalization in Romania meets the current needs of patients through a convergent …

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Fertility Preservation Strategies in Female Cancer Patients: Current Approaches and Future Directions

Nicolae Gică, Ancuța Năstac, Romina‐Marina Sima, Anca Maria Panaitescu et autres

Fertility-sparing treatments (FSTs) have gained importance for young female cancer patients, especially those with early-stage cervical, ovarian, and endometrial cancers. However, concerns about the long-term safety of these procedures, particularly in more advanced cancers, persist. A literature review was conducted using databases …

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411P Evaluation of ICG-guided axillary reverse mapping in breast cancer surgery: A retrospective observational study

Ancuța Năstac, I Popescu, Gabriela Adriana Filip

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Cutaneous Paraneoplastic Syndromes in Colorectal Cancer Patients

Vlad Ionescu, Gina Gheorghe, Teodor Florin Georgescu, Vlad Buică et autres

Despite many advances in the management of patients with colorectal cancer, this malignancy remains the second leading cause of cancer death worldwide. One of the keys to improve the prognosis of these patients is diagnosis in early stages, making them eligible for …

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Maternal and Fetal Complications in Pregnant Women with Neurofibromatosis Type 1: Literature Review and Two Case Reports

Ancuța Năstac, Anca Maria Panaitescu, Iulia Huluță, Nicolae Gică et autres

Neurofibromatosis is a genetic disorder arising de novo or with an autosomal dominant transmission that typically presents either at birth or in early childhood, manifesting through distinctive clinical features such as multiple café-au-lait spots, benign tumors in the skin, bone enlargement, and …

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Infectious Complications in Patients with Liver Cirrhosis

Ionela BACANU, Vlad-Alexandru IONESCU, Gina Gheorghe, Ancuța Năstac et autres

Introduction: Liver cirrhosis (LC) represents a major public health problem, with high morbidity and mortality rates. Materials and methods: We conducted an observational, descriptive, retrospective study in which we included 198 patients with LC hospitalized in the Clinical Emergency Hospital Bucharest over …