Accès ouvert
2025
article
OpenAlex
Bianca Raffaelli, Janu Thuraiaiyah, Rune H. Christensen, Haidar M. Al‐Khazali et autres
BACKGROUND: Migraine frequently co-exists with psychiatric comorbidities, including anxiety, depression, and sleep disturbances. Erenumab, a monoclonal antibody targeting the calcitonin gene-related peptide receptor, effectively reduces migraine frequency, but its impact on psychiatric symptoms remains unclear. This study evaluated the effects of erenumab …
dk, de, ch
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Accès ouvert
2025
article
OpenAlex
Peter J. Goadsby, Elena Ruiz de la Torre, Antoinette MaassenVanDenBrink, Pablo Irimia et autres
BackgroundThe stigma associated with migraine impacts patients' quality of life, mental health and their willingness to seek treatment. The present study aimed to gain insights into the stigma from the patient's perspective and to assess migraine knowledge among people without the condition.MethodsThis …
gb, nl, es, gr, dk, at
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Accès ouvert
2025
review
OpenAlex
Robin Arquizan, Anna G. Melchior, Rune Häckert Christensen, Haidar M. Al‐Khazali et autres
OBJECTIVE: To synthesize and interpret magnetic resonance angiography (MRA) findings on vascular changes after administration of established molecular migraine triggers in adults with migraine and in healthy individuals, focusing on the middle meningeal artery (MMA) and middle cerebral artery (MCA). METHODS: A …
dk
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Accès ouvert
2025
article
OpenAlex
William Kristian Karlsson, Rune H. Christensen, Haidar M. Al‐Khazali, Thomas Kallemose et autres
BACKGROUND: Soluble urokinase-plasminogen activator receptor (suPAR) is a biomarker of systemic inflammation and elevated in plasma of individuals with migraine with aura. As inflammatory cytokines can upregulate calcitonin gene-related peptide (CGRP), suPAR levels might be linked to response to CGRP-targeting therapies. Therefore, …
dk
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2025
article
OpenAlex
Jessica Ailani, Messoud Ashina, Susanne F. Awad, Scott N. Grossman et autres
This post hoc analysis of the DELIVER trial evaluated sustained ≥50% or ≥75% migraine responses over 72 weeks of eptinezumab treatment in patients with high-frequency episodic migraine (HFEM) or chronic migraine (CM).
us, dk, de
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Accès ouvert
2025
article
OpenAlex
Rune H. Christensen, Håkan Ashina, Haidar M. Al‐Khazali, Mario Ocampo‐Pineda et autres
OBJECTIVE: The involvement of cortical inflammation in migraine, particularly migraine with aura, has been a subject of considerable interest, but has proved challenging to demonstrate. We aimed to detect and characterize signs of cortical inflammation in adults with migraine using a novel, …
dk, ch, us, se
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Accès ouvert
2024
article
OpenAlex
Betel Tesfay, Håkan Ashina, Rune Häckert Christensen, Haidar M. Al‐Khazali et autres
Abstract Soluble urokinase plasminogen activator receptor (suPAR) has garnered attention as a potential blood-based biomarker for low-grade chronic inflammation. However, its specific association with migraine, including its subtypes, remains to be elucidated. We sought to examine the association of plasma suPAR levels …
dk
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Accès ouvert
2024
article
OpenAlex
Cédric Gollion, Rune H. Christensen, Håkan Ashina, Haidar M. Al‐Khazali et autres
Cortical spreading depression (CSD) is associated with pronounced alterations in cerebral blood flow. These alterations can be captured using high-field functional magnetic resonance imaging (fMRI). While compelling clinical and experimental data suggest that CSD is involved in the pathogenesis of migraine aura, …
dk
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Accès ouvert
2024
article
OpenAlex
Hao‐Ruei Mei, M.N. Lam, Shrivatsa Ravindra Kulkarni, Håkan Ashina et autres
ABSTRACT: Human experimental studies have shown that levcromakalim, an ATP-sensitive potassium (K ATP ) channel opener, induces migraine attacks in people with migraine but not in healthy volunteers. However, the exact site of action for K ATP channels in migraine pathophysiology remains …
us, dk
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Accès ouvert
2024
review
OpenAlex
William Kristian Karlsson, Edoardo G. Ostinelli, Zixuan Alice Zhuang, Lili Kokoti et autres
OBJECTIVE: To compare all licensed drug interventions as oral monotherapy for the acute treatment of migraine episodes in adults. DESIGN: Systematic review and network meta-analysis. DATA SOURCES: Cochrane Central Register of Controlled Trials, Medline, Embase, ClinicalTrials.gov, EU Clinical Trials Register, WHO International …
dk, gb, gr, de
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Accès ouvert
2024
article
OpenAlex
Francesca Puledda, Simona Sacco, Hans‐Christoph Diener, Messoud Ashina et autres
CA extern
gb, it, de, dk, us, kr, Ghana, tr, es, Égypte, jp, au, tw, ar, br, nl, ir, be, cn
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Accès ouvert
2024
article
OpenAlex
Francesca Puledda, Simona Sacco, Hans‐Christoph Diener, Messoud Ashina et autres
BACKGROUND: In an effort to improve migraine management around the world, the International Headache Society (IHS) has here developed a list of practical recommendations for the acute pharmacological treatment of migraine. The recommendations are categorized into optimal and essential, in order to …
gb, it, de, dk, us, kr, Ghana, tr, es, Égypte, jp, au, ar, tw, br, nl, ir, be, cn
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