P. Sethupathi

Renoprotective Effects of Soluble Guanylate Cyclase (sGC) Activation vs. ACE Inhibition in a CKD Model with Volume/Salt-Dependent Hypertension

Karen A. Griffin, P. Sethupathi, Shehla Sheikh, G.A. Williamson et autres

Background: BP control using renin-angiotensin system (RAS) blockade is the current standard of care for CKD. However, outcomes remain suboptimal in part because adequate BP reductions are difficult to achieve in the volume expanded CKD states with RAS blockade even with additional …

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Stem cells from foreign body granulation tissue accelerate recovery from acute kidney injury

Janki Patel, Namrata Pancholi, Krishnamurthy P. Gudehithlu, P. Sethupathi et autres

BACKGROUND: In previous studies, we obtained mesenchymal stem cells called granulation tissue stem cells (GTSC) from a regenerating granulation tissue created by placing a foreign body in the subcutaneous tissue of rats. Here, we used GTSC to ameliorate ischemia/reperfusion-induced acute kidney injury …

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321: Il-17 Is a Mediator of Bleomycin-Induced Acute Lung Injury in Mice

R. Braun, A Martin, P. Sethupathi, Melissa Medina et autres

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195: Omental Stromal Cells (OSC) Abrogate Acute Lung Injury Associated with Allogenic Transplant in Abscence of Immunosuppression

R. Braun, A Martin, P. Sethupathi, Melissa Medina et autres

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229: Activated Omental Stromal Cells Ameliorate Bleomycin Induced Acute Lung Injury

A Martin, B Braun, Melissa Medina, Sneha Shah et autres

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Collagen V (Col V) Induced Autoimmune Mechanisms in Experimental Models of Acute Lung Injury (ALI).

R. Braun, Alicia Martín, P. Sethupathi, C.H. Wigfield et autres

303: Tolerance Induction to Collagen Type V (Col V) Prevents Fibrosis in the Bleomycin (Blm) Lung Injury Model

R. Braun, C.H. Wigfield, A Martin, P. Sethupathi et autres

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Determination of carbamylated hemoglobin by an enzyme immunoassay (ELISA) based on a novel antibody

Ashok K. Singh, Krishnamurthy P. Gudehithlu, P. Sethupathi, Ramin Sam et autres

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Induction of an HPV 6bL1-specific mucosal IgA response by DNA immunization

Carola Schreckenberger, P. Sethupathi, Amornrat Kanjanahaluethai, Martin Müller et autres

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Rabbit monoclonal antibodies: generating a fusion partner to produce rabbit-rabbit hybridomas.

H Spieker-Polet, P. Sethupathi, Pi-Chen Yam, Katherine L. Knight

During the last 15 years several laboratories have attempted to generate rabbit monoclonal antibodies, mainly because rabbits recognize antigens and epitopes that are not immunogenic in mice or rats, two species from which monoclonal antibodies are usually generated. Monoclonal antibodies from rabbits …

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VDJ genes in VHa2 allotype-suppressed rabbits. Limited germline VH gene usage and accumulation of somatic mutations in D regions

Jeffery A. Short, P. Sethupathi, S K Zhai, Katherine L. Knight

In this study we investigate the molecular genetic basis for VHa- Ig. Knowing that the expression of VHa allotype Ig is suppressed by neonatal injection of rabbits with anti-VHa allotype antibody, and that the decreased level of VHa allotype Ig, VHa+, in …

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