Profil bibliographique

Diane Lefranc

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

22Publications signalées
563Citations signalées
1Affiliations récentes

Les institutions déclarées

Centre Hospitalier Universitaire de Lille

Les domaines associés

Alzheimer's disease research and treatmentsMultiple Sclerosis Research StudiesGenetic Neurodegenerative DiseasesDiabetes and associated disordersHormonal Regulation and Hypertension

Les publications récentes

Accès ouvert 2015 article OpenAlex

Amyloid-β 11 C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials

Enchi Liu, Mark E. Schmidt, Richard A. Margolin, Reisa Anne Sperling et autres

OBJECTIVE: To evaluate the effects of bapineuzumab on brain β-amyloid (Aβ) burden using (11)C-Pittsburgh compound B ((11)C-PiB)-PET. METHODS: Two phase 3 clinical trials, 1 each in apolipoprotein APOE ε4 carriers and noncarriers, were conducted in patients with mild to moderate Alzheimer disease …

be, gb, us (code pays fourni par la source)

153 citations Neurology
Accès ouvert 2014 article OpenAlex

High‐affinity σ1 protein agonist reduces clinical and pathological signs of experimental autoimmune encephalomyelitis

Bénédicte Oxombre, Catalina Lee-Chang, Alain Duhamel, Magali Toussaint et autres

BACKGROUND AND PURPOSE: Selective agonists of the sigma-1 receptor (σ1 protein) are generally reported to protect against neuronal damage and modulate oligodendrocyte differentiation. Human and rodent lymphocytes possess saturable, high-affinity binding sites for compounds binding to the σ1 protein and potential immunomodulatory …

fr (code pays fourni par la source)

18 citations British Journal of Pharmacology
2012 article OpenAlex

Singularité des profils d’autoréactivité systémique en fonction de l’âge: relations avec la susceptibilité au neuropaludisme chez les sujets exposés en région endémique à Abidjan, Côte-d’Ivoire

R. Dassé, Diane Lefranc, Sylvain Dubucquoi, Patricia Dussart et autres

The impact of autoimmunity on malaria-infection evolution reported by various works has led us to compare reactive patterns of self-dependent systemic IgG from 54 patients aged less than 15 years old to those from 46 subjects older than 15 years. These subjects …

fr, Côte d’Ivoire (code pays fourni par la source)

1 citation Bulletin de la Société de pathologie exotique
2010 article OpenAlex

Autoimmune Polyendocrine Syndrome Type 1 in North-Western France: AIRE Gene Mutation Specificities and Severe Forms Needing Immunosuppressive Therapies

Emmanuelle Proust-Lemoine, Pascale Saugier-Véber, Diane Lefranc, Sylvain Dubucquoi et autres

BACKGROUND: Autoimmune polyendocrine syndrome type 1 (APS1) has been poorly evaluated in France. We focused on the north-western part of the country to describe clinical phenotypes, especially severe forms of the disease, and AIRE gene mutations. METHODS: Clinical and immunological data were …

fr, pl (code pays fourni par la source)

45 citations Hormone Research in Paediatrics
2009 article OpenAlex

Serum IgG repertoire in clinically isolated syndrome predicts multiple sclerosis

Hélène Zéphir, Diane Lefranc, Sylvain Dubucquoi, Jerome De Seze et autres

OBJECTIVE: We previously showed that serum IgG repertoires distinguished multiple sclerosis (MS) patients from healthy subjects and from patients with other inflammatory neurological diseases (OIND). We questioned whether the serum IgG repertoire of patients presenting a clinically isolated syndrome (CIS) could predict …

fr (code pays fourni par la source)

12 citations Multiple Sclerosis Journal
Notice OpenAlex

BNTIC News n’est pas le producteur de ces données. Les publications sont interrogées à la demande dans Crossref, OpenAIRE, DOAJ, Europe PMC, HAL, DataCite, AfricArXiv, ROR et la Banque mondiale, sans clé d’accès. OpenAlex reste optionnel. Aucun service payant n’est nécessaire et aucune donnée externe n’est enregistrée en base. Consulter les sources et leurs limites.