Simran Sarin

Validation of Automated Software for Guttae Quantification in Fuchs Endothelial Corneal Dystrophy

Simran Sarin, Jérôme Abou Assi, Jessica M. Skeie, Pierre Deman et autres

Purpose: Corneal guttae are the hallmark pathologic phenotype of Fuchs endothelial corneal dystrophy (FECD). Tools performing quantitative analysis of guttae and their changes over time are needed as medical therapies advance. We developed and validated a novel automated software platform that reports …

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Restorative Community Building Practices: A Train-the-Trainer Workshop for Medical Students, Staff, and Faculty

Christopher L. Klasson, Ada Gregory, Ashrita Raghuram, Simran Sarin et autres

Introduction: : Restorative practices (RPs) are part of an emerging field that examines ways to build, strengthen, and manage relationships in organizations and communities, an approach that is gaining traction in the medical field.We describe the design and implementation of a day-long …

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Corneal transplantation wound dehiscence after penetrating keratoplasty and deep anterior lamellar keratoplasty

Simran Sarin, Mark A. Greiner, Gregory A. Schmidt, Kanwal S. Matharu et autres

PURPOSE: To study clinical characteristics and outcomes of penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK) wound dehiscence. METHODS: This retrospective case series assessed PK and DALK recipients with wound dehiscence at a single institution. We evaluated relationships between dehiscence etiologies, …

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Proof-of-Concept Study of a Sutureless Glycerin-Preserved Corneal Plug for Perforation Repair: Cufflink Design, Eye Bank Processing, and Ex Vivo Burst Pressure Testing

Evan Balk, Simran Sarin, Aaron Dotson, Luke Grandgenett et autres

Purpose: To develop and evaluate a sutureless, cufflink-shaped corneal plug for managing keratolytic corneal perforations and to establish an ex vivo perforation model for plug testing. Methods: We designed a cufflink-shaped corneal plug with 2 leaflets separated by an encircling groove. Plugs …

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Functional Assessment of Fuchs Endothelial Corneal Dystrophy in the National Advanced Driving Simulator: Initial Study of Nighttime Glare and Scheimpflug Imaging

Simran Sarin, Matthew Kigin, Evan Balk, Ryan J. Diel et autres

PURPOSE: The aim of this study was to quantify nighttime driving differences in patients with Fuchs endothelial corneal dystrophy (FECD) using the FDA-validated National Advanced Driving Simulator MiniSim. METHODS: We conducted a pilot study to calculate sample size, followed by a prospective …

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Influence of the time of day on axial length and choroidal thickness changes to hyperopic and myopic defocus in human eyes

Daniel Moderiano, Michelle Do, Sam Hobbs, Vy Lam et autres

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Time of the day influences the response to optical defocus in human eyes

Ranjay Chakraborty, Michelle Do, Sam Hobbs, Vy Lam et autres

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Impact of Reciprocity in Information Spreading Using Epidemic Model Variants

Rishabh Narang, Simran Sarin, Prajjwal Singh, Rinkaj Goyal

The use of online social networks has become a standard medium of social interactions and information spreading. Due to the significant amount of data available online, social network analysis has become apropos to the researchers of diverse domains to study and analyse …

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Commissioning of a metal vapor laser for the illumination of high speed motion pictures (projectile analysis)

D.J. Wehrlen, Simran Sarin

An effort to produce high-speed (20000 frames/s) motion pictures for the purpose of projectile analysis using a pulse-mode copper vapor laser as the sole illumination source was conducted. A single-shaft rotating prism camera was successfully synchronized with a 20-W continuous average power, …

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