Galia Avrahami

["Stronger Than Yourself": An Integrative Intervention Program to Improve Medication Adherence and Therapeutic Engagement in Pediatric Oncology Patients].

Raviv Peleg, Galia Avrahami, Tamar Natanzon, Michal Dayan‐Sharabi et autres

INTRODUCTION: This article presents the "Stronger Than Yourself" program, developed within the integrative medicine service of the Oncology Department of Schneider Children's Medical Center of Israel. The program was designed to improve treatment adherence among pediatric oncology patients, with particular emphasis on …

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Risk factors for mortality and re-admission of children with hematological malignancies to the intensive care unit due to sepsis

Shlomit Barzilai‐Birenboim, David M. Zucker, Galia Avrahami, Sarah Elitzur et autres

Children with hematological malignancies, are often hospitalized in pediatric intensive care units (PICU) for sepsis with high mortality and re-admission rates. Risk factors for both are inconsistent. We reviewed data of 190 admissions of children with hematological malignancies to PICU for sepsis. …

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PP124 Topic: AS13–Hematology/Oncology/Stem Cell Transplant/Immunology: ARE EXISTING MORTALITY PREDICTION MODELS SUITABLE FOR PEDIATRIC HEMATOLOGY/ONCOLOGY PATIENTS ADMITTED TO THE PEDIATRIC INTENSIVE CARE UNIT DUE TO SEPSIS?

Talya Wittmann Dayagi, Ronit Nirel, Galia Avrahami, Shirah Amar et autres

Aims & Objectives: Children with hemato-oncological diseases or post-stem cell transplantation (SCT), are highly susceptible to life-threatening infections, constituting a significant portion of pediatric intensive care unit (PICU) admissions due to sepsis. Standard pediatric prognostic tools may not adequately assess illness severity …

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A Need for a Novel Survival Risk Scoring System for Intensive Care Admissions Due to Sepsis in Pediatric Hematology/Oncology Patients

Talya Wittmann Dayagi, Ronit Nirel, Galia Avrahami, Shira Amar et autres

Background: Children with hemato-oncological diseases or following stem cell transplantation (SCT) are at high risk for life-threatening infections; sepsis in this population constitutes a substantial proportion of pediatric intensive care unit (PICU) admissions. The current pediatric prognostic scoring tools to evaluate illness …

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Thrombin Generation Is Differentially Affected By Anticoagulants in Patients with Acute Lymphoblastic Leukemia - an Ex-Vivo Study

Avi Leader, Sarah Elitzur, Baruch Gavrieli, Henri M.H. Spronk et autres

Background: Venous thromboembolism (VTE) is a frequent complication in patients with acute lymphoblastic leukemia (ALL). Low molecular weight heparin (LMWH) reduces the risk of VTE in ALL, but is not well tolerated in children. VTE rates remain unacceptably high in adults despite …

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Elevated intraocular pressure in children with acute lymphoblastic leukaemia: A prospective study

Shlomit Barzilai‐Birenboim, Sarah Elitzur, Ronit Nirel, Miriam Ehrenberg et autres

Most childhood acute lymphoblastic leukaemia (ALL) protocols include high-dose steroid therapy. However, the known potential of high-dose steroids to significantly elevate intraocular pressure (IOP) and lead to glaucomatous optic neuropathy has not been intensively investigated in children with ALL. Moreover, as children …

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Pediatric myelodysplastic syndrome with inflammatory manifestations: Diagnosis, genetics, treatment, and outcome

Asaf David Yanir, Aviva C. Krauss, Jerry Stein, Orna Steinberg‐Shemer et autres

BACKGROUND: Inflammatory manifestations (IM) are well described in adult patients with myelodysplastic syndrome (MDS), but the presentation is highly variable and no standardized treatment exists. This phenomenon is rarely reported in children. As more pediatric patients are hematopoietic stem cell transplantation (HSCT) …

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Bone pain at leukemia diagnosis and other risk factors for symptomatic osteonecrosis in children with acute lymphoblastic leukemia

Shlomit Barzilai‐Birenboim, Joanne Yacobovich, Yair Zalcberg, Nira Arad‐Cohen et autres

BACKGROUND: Osteonecrosis is a major cause of acute and long-lasting complications of acute lymphoblastic leukemia (ALL) therapy in children. Our study aimed to evaluate the prevalence, characteristics, risk factors, and outcome of osteonecrosis in children with ALL. PROCEDURE: The cohort included 559 …

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Long-term ovarian reserve and fertility outcomes in female survivors of childhood acute lymphoblastic leukemia

Sarah Elitzur, Shani Frank, Tal Goshen‐Lago, Shlomit Barzilai‐Birenboim et autres

Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy, yet data regarding long-term ovarian reserve of female survivors are limited. The aim of this study was to investigate whether there is a differential pattern of anti-Mullerian hormone (AMH) levels in female …

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Venous Thromboembolism and Its Risk Factors in Children with Acute Lymphoblastic Leukemia in Israel: A Population-Based Study

Shlomit Barzilai‐Birenboim, Ronit Nirel, Nira Arad‐Cohen, Galia Avrahami et autres

Venous thromboembolism (VTE) is a serious complication of acute lymphoblastic leukemia (ALL) therapy. The aim of this population-based study was to evaluate the rate, risk factors, and long-term sequelae of VTE in children treated for ALL. The cohort included 1191 children aged …

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Thrombophilia screening and thromboprophylaxis may benefit specific ethnic subgroups with paediatric acute lymphoblastic leukaemia

Shlomit Barzilai‐Birenboim, Nira Arad‐Cohen, Ronit Nirel, Galia Avrahami et autres

This study investigated the prevalence of inherited thrombophilia, risk of venous thromboembolism (VTE) and benefit of low molecular weight heparin prophylaxis in 476 Israeli children with acute lymphoblastic leukaemia (ALL) treated between 2004 and 2016. Thrombophilia was found in 15·5%. Arab children …

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Growth and pubertal patterns in young survivors of childhood acute lymphoblastic leukemia

Sara Elitzur, Revital Houri-Shtrecher, Michal Yackobovitz-Gavan, Galia Avrahami et autres

Several previous studies had focused on the early risk of metabolic syndrome or its components in survivors of childhood acute lymphoblastic leukaemia (ALL), while fewer data are available on pubertal development in these subjects. The merit of this study was to carefully …