G. Danglot

Two populations of double minute chromosomes harbor distinct amplicons, the MYC locus at 8q24.2 and a 0.43-Mb region at 14q24.1, in the SW613-S human carcinoma cell line

Marine Guillaud-Bataille, Olivier Brison, G. Danglot, Christian Lavialle et autres

High-level amplifications observed in tumor cells are usually indicative of genes involved in oncogenesis. We report here a high resolution characterization of a new amplified region in the SW613-S carcinoma cell line. This cell line contains tumorigenic cells displaying high-level MYC amplification …

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High resolution Genome-wide analysis of chromosomal alterations

S. Toujani, Philippe Dessen, Nathalie Ithzar, G. Danglot et autres

Supplementary Material for: Two populations of double minute chromosomes harbor distinct amplicons, the MYC locus at 8q24.2 and a 0.43-Mb region at 14q24.1, in the SW613-S human carcinoma cell line

Marine Guillaud-Bataille, Olivier Brison, G. Danglot, Christian Lavialle et autres

High-level amplifications observed in tumor cells are usually indicative of genes involved in oncogenesis. We report here a high resolution characterization of a new amplified region in the SW613-S carcinoma cell line. This cell line contains tumorigenic cells displaying high-level MYC amplification …

MDM2 amplification in a primary alveolar rhabdomyosarcoma displaying a t(2;13)(q35;q14)

Mounira Meddeb, A. Valent, G. Danglot, V.C. Nguyen et autres

This report describes a case of rhabdomyosarcoma associated with a 2;13 translocation and multiple double minute chromosomes. The origin of the amplified DNA was identified using comparative genomic hybridization, which pinpointed a unique spot at 12q13-->q14. Band 12q13 has been shown to …

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Contents, Vol. 73, 1996

Nigel K. Spurr, Susan L. Naylor, О. В. Зацепина, Christian Schöfer et autres

Author Index, Vol. 73, 1996

Nigel K. Spurr, Susan L. Naylor, О. В. Зацепина, Christian Schöfer et autres

High promoter hypermethylation frequency of p14/ARF in supratentorial PNET but not in medulloblastoma

M M Inda, J Muñoz, P. Coullin, Didier Fauvet et autres

AIMS: Medulloblastoma (MB) is the most common primitive neuroectodermal tumour (PNET) of the central nervous system. Although supratentorial PNET (sPNET) and MB are histologically similar, their clinical behaviour differs, sPNET being more aggressive than MB. The aim of this study was to …

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Duplication of the Ph-chromosome as a possible mechanism of resistance to imatinib mesylate in patients with chronic myelogenous leukemia

A. Ossard-Receveur, Alain Bernheim, Bernard Clausse, G. Danglot et autres

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Genetic heterogeneity in supratentorial and infratentorial primitive neuroectodermal tumours of the central nervous system

M M Inda, Christine Pérot, Marine Guillaud-Bataille, G. Danglot et autres

AIMS: Medulloblastoma (MB), a kind of infratentorial primitive neuroectodermal tumour (PNET), is the most frequent malignant brain tumour in childhood. In contrast, supratentorial PNET (sPNET) are very infrequent tumours, but they are histologically similar to MB, although they present a worse clinical …

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Gain of Chromosome Arm 17q and Adverse Outcome in Patients with Neuroblastoma

Nick Bown, Simon Cotterill, Maria Łastowska, Seamus O’Neill et autres

BACKGROUND: Gain of genetic material from chromosome arm 17q (gain of segment 17q21-qter) is the most frequent cytogenetic abnormality of neuroblastoma cells. This gain has been associated with advanced disease, patients who are > or =1 year old, deletion of chromosome arm …

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Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization

Agnès Marchio, Mounira Meddeb, Pascal Pineau, G. Danglot et autres

Chromosomal aberrations associated with hepatocellular carcinoma (HCC) were previously characterized by focusing on changes in particular known genes at the assigned loci, but not those in unidentified genes affected at other loci in whole metaphase chromosomes. In the present study, we examined …

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Assignment of the NTRK4 (trkE) gene to chromosome 6p21

A. Valent, Mounira Meddeb, G. Danglot, A. Duverger et autres

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