J Muñoz

Liver X Receptor Agonist Modifies the DNA Methylation Profile of Synapse and Neurogenesis-Related Genes in the Triple Transgenic Mouse Model of Alzheimer’s Disease

Adrián Gabriel Sandoval-Hernández, Hernán Guillermo Hernández, Alejandro Restrepo, J Muñoz et autres

co, es (code pays fourni par la source)

Molecular genetics of astrocytomas

J Muñoz, Xing Hua Fan, M M Inda, Javier S. Castresana

Astrocytomas are the most frequent group of intracranial tumors. Among them, glioblastoma is the most aggressive one. In this review we will describe the most common genetic abnormalities found out in astrocytomas. We will refer to the epidermal growth factor receptor (EGFR), …

es (code pays fourni par la source)

High promoter hypermethylation frequency of p14/ARF in supratentorial PNET but not in medulloblastoma

M M Inda, J Muñoz, P. Coullin, Didier Fauvet et autres

AIMS: Medulloblastoma (MB) is the most common primitive neuroectodermal tumour (PNET) of the central nervous system. Although supratentorial PNET (sPNET) and MB are histologically similar, their clinical behaviour differs, sPNET being more aggressive than MB. The aim of this study was to …

fr, es (code pays fourni par la source)

Silencing of DMBT1 in neuroblastoma cell lines is not due to methylation of CCWGG motifs on its promoter.

J Muñoz, Javier S. Castresana

DMBT1 is one of the putative suppressor genes on 10q25-qter, which frequently lacks expression in many different kind of tumors, such as glioblastoma, and lung, esophageal and colorectal cancer. However, little is known about the reasons for this lack of expression in …

es (code pays fourni par la source)