Accès ouvert
2025
article
OpenAlex
Line Kristensen, Sky Rohrer, Jacob Johansen, Lone Hoffmann et autres
BACKGROUND AND PURPOSE: Preclinical studies report a favourable normal tissue-sparing FLASH effect. Most studies report single-fraction irradiations. The interplay between fractionation and FLASH sparing is highly relevant for clinical translation but is scarce in the literature. This study compared the tissue-sparing effect …
dk
(code pays fourni par la source)
2025
article
OpenAlex
Line Kristensen, Sky Rohrer, Jacob Johansen, Lone Hoffmann et autres
Accès ouvert
2025
article
OpenAlex
Line Kristensen, Sky Rohrer, Lone Hoffmann, Lars Hjorth Præstegaard et autres
BACKGROUND AND PURPOSE: Dose-response modification of FLASH has previously been established for acute skin toxicity in protons. This study used a similar experimental setup to quantify the dose-response modification of electron FLASH irradiation for acute skin- and late fibrotic toxicity in mice. …
dk
(code pays fourni par la source)
Accès ouvert
2025
preprint
OpenAlex
Line Kristensen, Sky Rohrer, Jacob Johansen, Lone Hoffmann et autres
dk
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Line Kristensen, P.R. Poulsen, Eleni Kanouta, Sky Rohrer et autres
Objective: A favorable effect of ultra-high dose rate (FLASH) radiation on normal tissue-sparing has been indicated in several preclinical studies. In these studies, the adverse effects of radiation damage were reduced without compromising tumor control. Most studies of proton FLASH investigate these …
dk, de
(code pays fourni par la source)
2024
article
OpenAlex
Line Kristensen, P.R. Poulsen, Eleni Kanouta, Sky Rohrer et autres
1994
article
OpenAlex
Jack Rohrer, Sky Rohrer, Adel L. Barsoum, Joseph H. Coggin
We have previously demonstrated in several species that sarcomas, lymphomas, and carcinomas express a common Ag that cross-reacts with midgestation fetal cells. We also produced a mAb to that protein and characterized it as a 44-kDa glycoprotein. The cross-reactive immunity induced by …
us
(code pays fourni par la source)
1993
article
OpenAlex
Joseph H. Coggin, Sky Rohrer, R. D. Hester, Adel L. Barsoum et autres
OBJECTIVE: This article summarizes the phase-specific nature of a cell surface, 44-kd tumor-associated transplantation antigen glycoprotein expressed during early and middle gestation in a portion of rodent and human fetal cells during normal fetal tissue development and illustrates how this glycoprotein is …
us
(code pays fourni par la source)
1992
article
OpenAlex
Sky Rohrer, R. N. Sarli, Adel L. Barsoum, Raymond B. Hester et autres
BACKGROUND: Oncofetal antigens (OFAs) are found on the surface of murine and human midgestation fetal cells, in human and rodent tumor tissues, and on human and rodent tumor and embryonic cell lines but not in normal neonatal or adult human and rodent …
us
(code pays fourni par la source)
1990
article
OpenAlex
Raymond B. Hester, Sky Rohrer, P. I. Liu, Joseph H. Coggin
Two T-cell lines (XR11-4T and XR11-5T), established from radiation-induced, murine lymphoblastic lymphomas, were examined for the expression of class I major histocompatibility complex antigen and tumor induction. These cell lines expressed class I private determinants, H-2.9 and H-2.26, but not the monomorphic …
us
(code pays fourni par la source)
Accès ouvert
1988
article
OpenAlex
Joseph H. Coggin, Sky Rohrer, E D Leinbach, Raymond B. Hester et autres
X-ray-induced, lymphoblastic, T-cell lymphoma/leukemias from irradiated RF mice were observed to uniformly expressed a 44-kd oncofetal antigen (OFA). The OFA polypeptide was detected by flow cytometry, affinity column SDS-PAGE analysis, and immunoblotting with monoclonal antibody (MAb) 115 prepared against syngeneic mouse fetus. …
us
(code pays fourni par la source)
1982
article
OpenAlex
Sky Rohrer, B S Baliga, Robert M. Suskind